IT7927920A0 - Derivati mercaptoacilici di acidi 4,5-diidro-1h-pirrol-2-carbossilici e di acidi 1,4,5,6-tetraidropiridin-2-carbossi lici. - Google Patents

Derivati mercaptoacilici di acidi 4,5-diidro-1h-pirrol-2-carbossilici e di acidi 1,4,5,6-tetraidropiridin-2-carbossi lici.

Info

Publication number
IT7927920A0
IT7927920A0 IT7927920A IT2792079A IT7927920A0 IT 7927920 A0 IT7927920 A0 IT 7927920A0 IT 7927920 A IT7927920 A IT 7927920A IT 2792079 A IT2792079 A IT 2792079A IT 7927920 A0 IT7927920 A0 IT 7927920A0
Authority
IT
Italy
Prior art keywords
carboxylic acids
mercaptoacylic
tetrahydropyridin
pyrrol
dihydro
Prior art date
Application number
IT7927920A
Other languages
English (en)
Other versions
IT1126510B (it
Inventor
Miguel A Ondetti
Michael E Condon
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT7927920A0 publication Critical patent/IT7927920A0/it
Application granted granted Critical
Publication of IT1126510B publication Critical patent/IT1126510B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IT27920/79A 1978-12-08 1979-12-07 Derivati mercaptoacilici di acidi 4,5-diidro-1h-pirrol-2-carbossilici e di acidi 1,4,5,6-tetraidropiridin-2-carbussilici IT1126510B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/967,827 US4198515A (en) 1978-12-08 1978-12-08 Mercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids

Publications (2)

Publication Number Publication Date
IT7927920A0 true IT7927920A0 (it) 1979-12-07
IT1126510B IT1126510B (it) 1986-05-21

Family

ID=25513389

Family Applications (1)

Application Number Title Priority Date Filing Date
IT27920/79A IT1126510B (it) 1978-12-08 1979-12-07 Derivati mercaptoacilici di acidi 4,5-diidro-1h-pirrol-2-carbossilici e di acidi 1,4,5,6-tetraidropiridin-2-carbussilici

Country Status (14)

Country Link
US (1) US4198515A (it)
JP (1) JPS5581858A (it)
AU (1) AU534762B2 (it)
BE (1) BE880495A (it)
CA (1) CA1132986A (it)
CH (1) CH641777A5 (it)
DE (1) DE2949180A1 (it)
FR (1) FR2443460A1 (it)
GB (1) GB2037285B (it)
IE (1) IE49122B1 (it)
IT (1) IT1126510B (it)
LU (1) LU81963A1 (it)
NL (1) NL7908593A (it)
ZA (1) ZA796225B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4241076A (en) * 1978-02-21 1980-12-23 E. R. Squibb & Sons, Inc. Halogenated substituted mercaptoacylamino acids
ZA794723B (en) * 1978-09-11 1980-08-27 Univ Miami Anti-hypertensive agents
US4311697A (en) * 1978-12-22 1982-01-19 E. R. Squibb & Sons, Inc. Derivatives of mercaptoacyl prolines and pipecolic acids
US4692458A (en) * 1980-03-05 1987-09-08 University Of Miami Anti-hypertensive agents
DE3165669D1 (en) * 1980-06-23 1984-09-27 Squibb & Sons Inc Azido, imido, amido and amino derivatives of mercaptoacyl prolines and pipecolic acids having hypotensive activity
US4307110A (en) * 1980-09-12 1981-12-22 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of 3-substituted proline derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4091024A (en) * 1976-12-03 1978-05-23 E. R. Squibb & Sons, Inc. Pyrrolidine and piperidine-2-carboxylic acid derivatives
US4129566A (en) * 1978-02-15 1978-12-12 E. R. Squibb & Sons, Inc. Derivatives of dehydrocyclicimino acids
US4113715A (en) * 1977-01-17 1978-09-12 E. R. Squibb & Sons, Inc. Amino acid derivatives
US4108886A (en) * 1977-03-11 1978-08-22 E. R. Squibb & Sons, Inc. Thiopropanoylamino acid derivatives
US4070361A (en) * 1977-04-21 1978-01-24 E. R. Squibb & Sons, Inc. Mercaptoalkylsulfonyl proline and pipecolic acid and esters thereof

Also Published As

Publication number Publication date
BE880495A (fr) 1980-06-09
CH641777A5 (fr) 1984-03-15
JPS5581858A (en) 1980-06-20
US4198515A (en) 1980-04-15
CA1132986A (en) 1982-10-05
JPH0128019B2 (it) 1989-05-31
FR2443460A1 (fr) 1980-07-04
AU5311779A (en) 1980-06-12
GB2037285B (en) 1983-01-19
IT1126510B (it) 1986-05-21
GB2037285A (en) 1980-07-09
IE49122B1 (en) 1985-08-07
FR2443460B1 (it) 1983-06-03
AU534762B2 (en) 1984-02-16
NL7908593A (nl) 1980-06-10
IE792328L (en) 1980-06-08
DE2949180A1 (de) 1980-06-26
ZA796225B (en) 1980-11-26
LU81963A1 (fr) 1980-04-22

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