BE880495A - Derives mercaptoacyles d'acides 4,5-dihydro-1h-pyrrole-2-carboxyliques et d'acides 1,4,5,6-tetrahydro-pyridine-2-carboxyliques - Google Patents
Derives mercaptoacyles d'acides 4,5-dihydro-1h-pyrrole-2-carboxyliques et d'acides 1,4,5,6-tetrahydro-pyridine-2-carboxyliquesInfo
- Publication number
- BE880495A BE880495A BE0/198477A BE198477A BE880495A BE 880495 A BE880495 A BE 880495A BE 0/198477 A BE0/198477 A BE 0/198477A BE 198477 A BE198477 A BE 198477A BE 880495 A BE880495 A BE 880495A
- Authority
- BE
- Belgium
- Prior art keywords
- carboxylic acids
- pyrrole
- tetrahydro
- dihydro
- pyridine
- Prior art date
Links
- SYHALQNMKJVYAZ-UHFFFAOYSA-N 1,2,3,4-tetrahydropyridin-1-ium-6-carboxylate Chemical class OC(=O)C1=CCCCN1 SYHALQNMKJVYAZ-UHFFFAOYSA-N 0.000 title 1
- CELGZUZZTJEZAF-UHFFFAOYSA-N 2,3-dihydro-1h-pyrrole-5-carboxylic acid Chemical class OC(=O)C1=CCCN1 CELGZUZZTJEZAF-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/967,827 US4198515A (en) | 1978-12-08 | 1978-12-08 | Mercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE880495A true BE880495A (fr) | 1980-06-09 |
Family
ID=25513389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE0/198477A BE880495A (fr) | 1978-12-08 | 1979-12-07 | Derives mercaptoacyles d'acides 4,5-dihydro-1h-pyrrole-2-carboxyliques et d'acides 1,4,5,6-tetrahydro-pyridine-2-carboxyliques |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4198515A (fr) |
| JP (1) | JPS5581858A (fr) |
| AU (1) | AU534762B2 (fr) |
| BE (1) | BE880495A (fr) |
| CA (1) | CA1132986A (fr) |
| CH (1) | CH641777A5 (fr) |
| DE (1) | DE2949180A1 (fr) |
| FR (1) | FR2443460A1 (fr) |
| GB (1) | GB2037285B (fr) |
| IE (1) | IE49122B1 (fr) |
| IT (1) | IT1126510B (fr) |
| LU (1) | LU81963A1 (fr) |
| NL (1) | NL7908593A (fr) |
| ZA (1) | ZA796225B (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4241076A (en) * | 1978-02-21 | 1980-12-23 | E. R. Squibb & Sons, Inc. | Halogenated substituted mercaptoacylamino acids |
| ZA794723B (en) * | 1978-09-11 | 1980-08-27 | Univ Miami | Anti-hypertensive agents |
| US4311697A (en) * | 1978-12-22 | 1982-01-19 | E. R. Squibb & Sons, Inc. | Derivatives of mercaptoacyl prolines and pipecolic acids |
| US4692458A (en) * | 1980-03-05 | 1987-09-08 | University Of Miami | Anti-hypertensive agents |
| EP0042639B1 (fr) * | 1980-06-23 | 1984-08-22 | E.R. Squibb & Sons, Inc. | Dérivés azido, imide, amide et amino de mercaptoacylprolines et d'acides pipécoliques doués d' activité hypotensive |
| US4307110A (en) * | 1980-09-12 | 1981-12-22 | E. R. Squibb & Sons, Inc. | Mercaptoacyl derivatives of 3-substituted proline derivatives |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4105776A (en) * | 1976-06-21 | 1978-08-08 | E. R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
| US4046889A (en) * | 1976-02-13 | 1977-09-06 | E. R. Squibb & Sons, Inc. | Azetidine-2-carboxylic acid derivatives |
| AU509899B2 (en) * | 1976-02-13 | 1980-05-29 | E.R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
| US4091024A (en) * | 1976-12-03 | 1978-05-23 | E. R. Squibb & Sons, Inc. | Pyrrolidine and piperidine-2-carboxylic acid derivatives |
| US4129566A (en) * | 1978-02-15 | 1978-12-12 | E. R. Squibb & Sons, Inc. | Derivatives of dehydrocyclicimino acids |
| US4113715A (en) * | 1977-01-17 | 1978-09-12 | E. R. Squibb & Sons, Inc. | Amino acid derivatives |
| US4108886A (en) * | 1977-03-11 | 1978-08-22 | E. R. Squibb & Sons, Inc. | Thiopropanoylamino acid derivatives |
| US4070361A (en) * | 1977-04-21 | 1978-01-24 | E. R. Squibb & Sons, Inc. | Mercaptoalkylsulfonyl proline and pipecolic acid and esters thereof |
-
1978
- 1978-12-08 US US05/967,827 patent/US4198515A/en not_active Expired - Lifetime
-
1979
- 1979-11-15 CA CA339,887A patent/CA1132986A/fr not_active Expired
- 1979-11-19 ZA ZA00796225A patent/ZA796225B/xx unknown
- 1979-11-22 AU AU53117/79A patent/AU534762B2/en not_active Ceased
- 1979-11-27 NL NL7908593A patent/NL7908593A/nl not_active Application Discontinuation
- 1979-11-29 FR FR7929390A patent/FR2443460A1/fr active Granted
- 1979-11-29 GB GB7941322A patent/GB2037285B/en not_active Expired
- 1979-12-04 IE IE2328/79A patent/IE49122B1/en unknown
- 1979-12-06 DE DE19792949180 patent/DE2949180A1/de not_active Ceased
- 1979-12-07 IT IT27920/79A patent/IT1126510B/it active
- 1979-12-07 CH CH1088879A patent/CH641777A5/fr not_active IP Right Cessation
- 1979-12-07 LU LU81963A patent/LU81963A1/fr unknown
- 1979-12-07 BE BE0/198477A patent/BE880495A/fr not_active IP Right Cessation
- 1979-12-08 JP JP15970479A patent/JPS5581858A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| US4198515A (en) | 1980-04-15 |
| CA1132986A (fr) | 1982-10-05 |
| GB2037285B (en) | 1983-01-19 |
| FR2443460A1 (fr) | 1980-07-04 |
| IE49122B1 (en) | 1985-08-07 |
| JPH0128019B2 (fr) | 1989-05-31 |
| CH641777A5 (fr) | 1984-03-15 |
| IE792328L (en) | 1980-06-08 |
| AU534762B2 (en) | 1984-02-16 |
| IT1126510B (it) | 1986-05-21 |
| AU5311779A (en) | 1980-06-12 |
| IT7927920A0 (it) | 1979-12-07 |
| NL7908593A (nl) | 1980-06-10 |
| GB2037285A (en) | 1980-07-09 |
| LU81963A1 (fr) | 1980-04-22 |
| FR2443460B1 (fr) | 1983-06-03 |
| ZA796225B (en) | 1980-11-26 |
| JPS5581858A (en) | 1980-06-20 |
| DE2949180A1 (de) | 1980-06-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: E.R. SQUIBB & SONS INC. Effective date: 19911231 |