IT7849419A0 - AMINOALKYLBENZE DERIVATIVES USEFUL AS PHARMACEUTICALS IN PARTICULAR FOR THE TREATMENT OF GASTRIC ULCERS AND SKIN ALLERGIES AND RELATED PRODUCTION PROCEDURE - Google Patents
AMINOALKYLBENZE DERIVATIVES USEFUL AS PHARMACEUTICALS IN PARTICULAR FOR THE TREATMENT OF GASTRIC ULCERS AND SKIN ALLERGIES AND RELATED PRODUCTION PROCEDUREInfo
- Publication number
- IT7849419A0 IT7849419A0 IT7849419A IT4941978A IT7849419A0 IT 7849419 A0 IT7849419 A0 IT 7849419A0 IT 7849419 A IT7849419 A IT 7849419A IT 4941978 A IT4941978 A IT 4941978A IT 7849419 A0 IT7849419 A0 IT 7849419A0
- Authority
- IT
- Italy
- Prior art keywords
- aminoalkylbenze
- pharmaceuticals
- treatment
- production procedure
- derivatives useful
- Prior art date
Links
- 208000007107 Stomach Ulcer Diseases 0.000 title 1
- 230000007815 allergy Effects 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
- C07C275/10—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/08—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/30—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to nitro or nitroso groups
- C07C279/32—N-nitroguanidines
- C07C279/36—Substituted N-nitroguanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/06—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/06—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
- C07C335/08—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of a saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB20660/77A GB1604674A (en) | 1977-05-17 | 1977-05-17 | Aminoalkyl-benzene derivatives |
| GB4012977 | 1977-09-27 | ||
| GB1744478 | 1978-05-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7849419A0 true IT7849419A0 (en) | 1978-05-17 |
| IT1156755B IT1156755B (en) | 1987-02-04 |
Family
ID=27257503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT7849419A IT1156755B (en) | 1977-05-17 | 1978-05-17 | AMINO ALKYLBENZENIC DERIVATIVES USEFUL AS PHARMACEUTICALS IN PARTICULAR FOR THE TREATMENT OF GASTRIC ULCERS AND SKIN ALLERGIES AND RELATED PRODUCTION PROCESS |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS53149936A (en) |
| AU (2) | AU523496B2 (en) |
| CH (2) | CH643238A5 (en) |
| DE (1) | DE2821410A1 (en) |
| DK (1) | DK214878A (en) |
| ES (1) | ES469953A1 (en) |
| FI (1) | FI781490A (en) |
| FR (2) | FR2401135A1 (en) |
| IE (1) | IE46886B1 (en) |
| IT (1) | IT1156755B (en) |
| NL (1) | NL7805344A (en) |
| NZ (1) | NZ187235A (en) |
| SE (1) | SE443558B (en) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4233302A (en) * | 1977-12-23 | 1980-11-11 | Glaxo Group Limited | Amine derivatives and pharmaceutical compositions containing them |
| AR228941A1 (en) * | 1978-04-26 | 1983-05-13 | Glaxo Group Ltd | PROCEDURE FOR PREPARING NEW DERIVATIVES OF 3,5-DIAMINO-1,2,4-TRIAZOLE WHICH ARE ACTIVE AGAINST HISTAMINIC RECEPTORS |
| DE3067920D1 (en) * | 1979-03-02 | 1984-06-28 | Glaxo Group Ltd | 1,2,4-triazole derivatives, processes for their production and pharmaceutical compositions containing them |
| JPS609750B2 (en) * | 1979-07-03 | 1985-03-12 | 帝国臓器製薬株式会社 | Novel N-substituted phenoxypropylamide compounds |
| JPS568352A (en) * | 1979-07-03 | 1981-01-28 | Shionogi & Co Ltd | Aminoalkylvenzene derivative |
| US4293557A (en) | 1979-07-03 | 1981-10-06 | Teikoku Hormone Mfg. Co., Ltd. | Antiulcer phenoxypropylamine derivatives |
| EP0029303B1 (en) * | 1979-10-22 | 1985-01-30 | Glaxo Group Limited | 1,2,4-triazole derivatives, processes for their production and pharmaceutical compositions containing them |
| US4238487A (en) * | 1979-10-31 | 1980-12-09 | Merck & Co., Inc. | Aminoalkyl benzofuran derivatives |
| FR2477537A1 (en) * | 1980-03-07 | 1981-09-11 | Francaise Sucrerie | NOVEL ACYLATED GUANIDINES, UREAS AND SUBSTITUTED UREAS, THEIR MANUFACTURING PROCESS AND THEIR APPLICATION AS MEDICAMENTS |
| US4490533A (en) * | 1980-12-22 | 1984-12-25 | Merck & Co., Inc. | Aminoalkyl pyridine derivatives |
| EP0057981A3 (en) | 1981-02-09 | 1982-08-25 | Beecham Group Plc | Aromatic compounds, processes for their preparation and their use |
| JPS57165348A (en) * | 1981-04-06 | 1982-10-12 | Teikoku Hormone Mfg Co Ltd | Novel aminoalkylbenzene derivative |
| US4526973A (en) * | 1981-05-18 | 1985-07-02 | Bristol-Myers Company | Chemical compounds |
| US4522943A (en) * | 1981-05-18 | 1985-06-11 | Bristol-Myers Company | Chemical compounds |
| IE53068B1 (en) * | 1981-06-15 | 1988-05-25 | Merck & Co Inc | Diamino isothiazole-1-oxides and -1,1-dioxides as gastic secretion inhibitors |
| AU8635482A (en) * | 1981-07-24 | 1983-01-27 | Glaxo Group Limited | Derivatives of amino 1,2,4-triazoles |
| US4411899A (en) * | 1981-12-21 | 1983-10-25 | Merck & Co., Inc. | Substituted derivatives of amino alkane diols as gastric secretion inhibitors |
| JPS5988458A (en) * | 1982-11-12 | 1984-05-22 | Toyama Chem Co Ltd | Amine derivative and its salt |
| JPH0639466B2 (en) * | 1987-08-03 | 1994-05-25 | 杏林製薬株式会社 | Urea derivative |
| JPH01131172A (en) * | 1987-08-28 | 1989-05-24 | Toyama Chem Co Ltd | Amine derivative and salt thereof and antiulcer agent containing said derivative and salt |
| DE69307310D1 (en) * | 1992-05-12 | 1997-02-20 | Zeria Pharm Co Ltd | NEW QUATERNARY AMMONIUM SALTS AND THEIR MEDICAL USE |
| TWI328009B (en) | 2003-05-21 | 2010-08-01 | Glaxo Group Ltd | Quinoline derivatives as phosphodiesterase inhibitors |
| CA2704199C (en) | 2007-11-01 | 2016-01-19 | Acucela Inc. | Amine derivative compounds for treating ophthalmic diseases and disorders |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL296978A (en) * | ||||
| US2785201A (en) * | 1953-12-24 | 1957-03-12 | Personnes A Responsabilite Lim | Compounds of bis quaternary ammonium derivatives of phenylethylamine |
| US3047628A (en) * | 1957-02-19 | 1962-07-31 | Hoffmann La Roche | Benzylamine derivatives |
| GB993581A (en) * | 1960-03-03 | 1965-05-26 | Wellcome Found | Phenoxyalkylguanidines and their synthesis and pharmaceutical preparations containing them |
| GB1338169A (en) * | 1971-03-09 | 1973-11-21 | Smith Kline French Lab | Ureas thioureas and guanidines |
| GB1421792A (en) * | 1973-05-17 | 1976-01-21 | Smith Kline French Lab | Heterocyclic substituted-1, 1-diamino-ethylene derivatives methods for their preparation and compositions containing them |
| JPS5227757A (en) * | 1975-08-26 | 1977-03-02 | Kyowa Hakko Kogyo Co Ltd | Preparation of 6-aminomethylnaphthalene derivatives |
-
1978
- 1978-05-09 IE IE940/78A patent/IE46886B1/en unknown
- 1978-05-10 NZ NZ187235A patent/NZ187235A/en unknown
- 1978-05-11 FI FI781490A patent/FI781490A/en not_active Application Discontinuation
- 1978-05-12 AU AU36067/78A patent/AU523496B2/en not_active Expired
- 1978-05-16 CH CH531578A patent/CH643238A5/en not_active IP Right Cessation
- 1978-05-16 SE SE7805591A patent/SE443558B/en unknown
- 1978-05-16 DE DE19782821410 patent/DE2821410A1/en not_active Withdrawn
- 1978-05-16 DK DK214878A patent/DK214878A/en unknown
- 1978-05-17 IT IT7849419A patent/IT1156755B/en active
- 1978-05-17 JP JP5870678A patent/JPS53149936A/en active Granted
- 1978-05-17 NL NL7805344A patent/NL7805344A/en not_active Application Discontinuation
- 1978-05-17 FR FR7814594A patent/FR2401135A1/en active Granted
- 1978-05-17 ES ES469953A patent/ES469953A1/en not_active Expired
- 1978-10-03 FR FR7828239A patent/FR2398718A1/en active Granted
-
1982
- 1982-05-25 AU AU84117/82A patent/AU541144B2/en not_active Expired
- 1982-12-22 CH CH749182A patent/CH643233A5/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL7805344A (en) | 1978-11-21 |
| IE780940L (en) | 1978-11-17 |
| CH643233A5 (en) | 1984-05-30 |
| ES469953A1 (en) | 1979-09-16 |
| JPH0112744B2 (en) | 1989-03-02 |
| IE46886B1 (en) | 1983-10-19 |
| FR2398718A1 (en) | 1979-02-23 |
| JPS53149936A (en) | 1978-12-27 |
| FR2398718B1 (en) | 1982-10-15 |
| IT1156755B (en) | 1987-02-04 |
| AU3606778A (en) | 1979-11-15 |
| SE443558B (en) | 1986-03-03 |
| AU523496B2 (en) | 1982-07-29 |
| CH643238A5 (en) | 1984-05-30 |
| FI781490A (en) | 1978-11-18 |
| DK214878A (en) | 1978-11-18 |
| NZ187235A (en) | 1981-10-19 |
| AU541144B2 (en) | 1984-12-20 |
| FR2401135B1 (en) | 1983-08-19 |
| AU8411782A (en) | 1982-08-26 |
| SE7805591L (en) | 1978-11-18 |
| DE2821410A1 (en) | 1978-11-30 |
| FR2401135A1 (en) | 1979-03-23 |
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