FR2401135A1 - NEW DERIVATIVES OF AMINOALKYL-BENZENES AND METHODS FOR THEIR PREPARATION - Google Patents
NEW DERIVATIVES OF AMINOALKYL-BENZENES AND METHODS FOR THEIR PREPARATIONInfo
- Publication number
- FR2401135A1 FR2401135A1 FR7814594A FR7814594A FR2401135A1 FR 2401135 A1 FR2401135 A1 FR 2401135A1 FR 7814594 A FR7814594 A FR 7814594A FR 7814594 A FR7814594 A FR 7814594A FR 2401135 A1 FR2401135 A1 FR 2401135A1
- Authority
- FR
- France
- Prior art keywords
- benzenes
- aminoalkyl
- preparation
- methods
- new derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 aminoalkyl benzenes Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
- C07C275/10—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/08—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/30—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to nitro or nitroso groups
- C07C279/32—N-nitroguanidines
- C07C279/36—Substituted N-nitroguanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/06—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/06—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
- C07C335/08—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of a saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
Abstract
L'invention concerne de nouveaux aminoalkyl benzènes. Les composés conformes à l'invention répondent à la formule générale suivante :The invention relates to novel aminoalkyl benzenes. The compounds in accordance with the invention correspond to the following general formula:
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB20660/77A GB1604674A (en) | 1977-05-17 | 1977-05-17 | Aminoalkyl-benzene derivatives |
GB4012977 | 1977-09-27 | ||
GB1744478 | 1978-05-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2401135A1 true FR2401135A1 (en) | 1979-03-23 |
FR2401135B1 FR2401135B1 (en) | 1983-08-19 |
Family
ID=27257503
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7814594A Granted FR2401135A1 (en) | 1977-05-17 | 1978-05-17 | NEW DERIVATIVES OF AMINOALKYL-BENZENES AND METHODS FOR THEIR PREPARATION |
FR7828239A Granted FR2398718A1 (en) | 1977-05-17 | 1978-10-03 | NEW PRIMARY AMINES USEFUL FOR THE PREPARATION OF AMINOALKYL BENZENE DERIVATIVES |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7828239A Granted FR2398718A1 (en) | 1977-05-17 | 1978-10-03 | NEW PRIMARY AMINES USEFUL FOR THE PREPARATION OF AMINOALKYL BENZENE DERIVATIVES |
Country Status (13)
Country | Link |
---|---|
JP (1) | JPS53149936A (en) |
AU (2) | AU523496B2 (en) |
CH (2) | CH643238A5 (en) |
DE (1) | DE2821410A1 (en) |
DK (1) | DK214878A (en) |
ES (1) | ES469953A1 (en) |
FI (1) | FI781490A (en) |
FR (2) | FR2401135A1 (en) |
IE (1) | IE46886B1 (en) |
IT (1) | IT1156755B (en) |
NL (1) | NL7805344A (en) |
NZ (1) | NZ187235A (en) |
SE (1) | SE443558B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2477537A1 (en) * | 1980-03-07 | 1981-09-11 | Francaise Sucrerie | NOVEL ACYLATED GUANIDINES, UREAS AND SUBSTITUTED UREAS, THEIR MANUFACTURING PROCESS AND THEIR APPLICATION AS MEDICAMENTS |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4233302A (en) * | 1977-12-23 | 1980-11-11 | Glaxo Group Limited | Amine derivatives and pharmaceutical compositions containing them |
AR228941A1 (en) * | 1978-04-26 | 1983-05-13 | Glaxo Group Ltd | PROCEDURE FOR PREPARING NEW DERIVATIVES OF 3,5-DIAMINO-1,2,4-TRIAZOLE WHICH ARE ACTIVE AGAINST HISTAMINIC RECEPTORS |
NO800583L (en) * | 1979-03-02 | 1980-09-03 | Glaxo Group Ltd | PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE TRIAZOLD DERIVATIVES |
JPS568352A (en) * | 1979-07-03 | 1981-01-28 | Shionogi & Co Ltd | Aminoalkylvenzene derivative |
US4293557A (en) | 1979-07-03 | 1981-10-06 | Teikoku Hormone Mfg. Co., Ltd. | Antiulcer phenoxypropylamine derivatives |
JPS609750B2 (en) * | 1979-07-03 | 1985-03-12 | 帝国臓器製薬株式会社 | Novel N-substituted phenoxypropylamide compounds |
DE3070073D1 (en) * | 1979-10-22 | 1985-03-14 | Glaxo Group Ltd | 1,2,4-triazole derivatives, processes for their production and pharmaceutical compositions containing them |
US4238487A (en) * | 1979-10-31 | 1980-12-09 | Merck & Co., Inc. | Aminoalkyl benzofuran derivatives |
US4490533A (en) * | 1980-12-22 | 1984-12-25 | Merck & Co., Inc. | Aminoalkyl pyridine derivatives |
EP0057981A3 (en) * | 1981-02-09 | 1982-08-25 | Beecham Group Plc | Aromatic compounds, processes for their preparation and their use |
JPS57165348A (en) * | 1981-04-06 | 1982-10-12 | Teikoku Hormone Mfg Co Ltd | Novel aminoalkylbenzene derivative |
US4526973A (en) * | 1981-05-18 | 1985-07-02 | Bristol-Myers Company | Chemical compounds |
US4522943A (en) * | 1981-05-18 | 1985-06-11 | Bristol-Myers Company | Chemical compounds |
IE53068B1 (en) * | 1981-06-15 | 1988-05-25 | Merck & Co Inc | Diamino isothiazole-1-oxides and -1,1-dioxides as gastic secretion inhibitors |
EP0071434B1 (en) * | 1981-07-24 | 1987-01-28 | Glaxo Group Limited | Heterocyclic derivatives |
US4411899A (en) * | 1981-12-21 | 1983-10-25 | Merck & Co., Inc. | Substituted derivatives of amino alkane diols as gastric secretion inhibitors |
JPS5988458A (en) * | 1982-11-12 | 1984-05-22 | Toyama Chem Co Ltd | Amine derivative and its salt |
JPH0639466B2 (en) * | 1987-08-03 | 1994-05-25 | 杏林製薬株式会社 | Urea derivative |
JPH01131172A (en) * | 1987-08-28 | 1989-05-24 | Toyama Chem Co Ltd | Amine derivative and salt thereof and antiulcer agent containing said derivative and salt |
US5574054A (en) * | 1992-05-12 | 1996-11-12 | Zeria Pharmaceutical Co., Ltd. | Quaternary ammonium salts and use thereof as medicine |
TWI328009B (en) | 2003-05-21 | 2010-08-01 | Glaxo Group Ltd | Quinoline derivatives as phosphodiesterase inhibitors |
CA2704199C (en) | 2007-11-01 | 2016-01-19 | Acucela Inc. | Amine derivative compounds for treating ophthalmic diseases and disorders |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE636468A (en) * | ||||
US2785201A (en) * | 1953-12-24 | 1957-03-12 | Personnes A Responsabilite Lim | Compounds of bis quaternary ammonium derivatives of phenylethylamine |
US3047628A (en) * | 1957-02-19 | 1962-07-31 | Hoffmann La Roche | Benzylamine derivatives |
US3099599A (en) * | 1960-03-03 | 1963-07-30 | Burroughs Wellcome Co | Method for treating infestations of nematodes |
FR2128505A1 (en) * | 1971-03-09 | 1972-10-20 | Smith Kline French Lab | |
FR2229417A1 (en) * | 1973-05-17 | 1974-12-13 | Smith Kline French Lab |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5227757A (en) * | 1975-08-26 | 1977-03-02 | Kyowa Hakko Kogyo Co Ltd | Preparation of 6-aminomethylnaphthalene derivatives |
-
1978
- 1978-05-09 IE IE940/78A patent/IE46886B1/en unknown
- 1978-05-10 NZ NZ187235A patent/NZ187235A/en unknown
- 1978-05-11 FI FI781490A patent/FI781490A/en not_active Application Discontinuation
- 1978-05-12 AU AU36067/78A patent/AU523496B2/en not_active Expired
- 1978-05-16 DE DE19782821410 patent/DE2821410A1/en not_active Withdrawn
- 1978-05-16 CH CH531578A patent/CH643238A5/en not_active IP Right Cessation
- 1978-05-16 SE SE7805591A patent/SE443558B/en unknown
- 1978-05-16 DK DK214878A patent/DK214878A/en unknown
- 1978-05-17 FR FR7814594A patent/FR2401135A1/en active Granted
- 1978-05-17 ES ES469953A patent/ES469953A1/en not_active Expired
- 1978-05-17 NL NL7805344A patent/NL7805344A/en not_active Application Discontinuation
- 1978-05-17 IT IT7849419A patent/IT1156755B/en active
- 1978-05-17 JP JP5870678A patent/JPS53149936A/en active Granted
- 1978-10-03 FR FR7828239A patent/FR2398718A1/en active Granted
-
1982
- 1982-05-25 AU AU84117/82A patent/AU541144B2/en not_active Expired
- 1982-12-22 CH CH749182A patent/CH643233A5/en not_active IP Right Cessation
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE636468A (en) * | ||||
US2785201A (en) * | 1953-12-24 | 1957-03-12 | Personnes A Responsabilite Lim | Compounds of bis quaternary ammonium derivatives of phenylethylamine |
US3047628A (en) * | 1957-02-19 | 1962-07-31 | Hoffmann La Roche | Benzylamine derivatives |
US3099599A (en) * | 1960-03-03 | 1963-07-30 | Burroughs Wellcome Co | Method for treating infestations of nematodes |
FR2128505A1 (en) * | 1971-03-09 | 1972-10-20 | Smith Kline French Lab | |
FR2229417A1 (en) * | 1973-05-17 | 1974-12-13 | Smith Kline French Lab |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2477537A1 (en) * | 1980-03-07 | 1981-09-11 | Francaise Sucrerie | NOVEL ACYLATED GUANIDINES, UREAS AND SUBSTITUTED UREAS, THEIR MANUFACTURING PROCESS AND THEIR APPLICATION AS MEDICAMENTS |
EP0035945A2 (en) * | 1980-03-07 | 1981-09-16 | Compagnie Francaise De Sucrerie | Acyl guanidines, ureas and substituted ureas, their preparation and their use as medicaments |
EP0035945A3 (en) * | 1980-03-07 | 1981-12-02 | Compagnie Francaise De Sucrerie | Acyl guanidines, ureas and substituted ureas, their preparation and their use as medicaments |
Also Published As
Publication number | Publication date |
---|---|
FR2398718A1 (en) | 1979-02-23 |
CH643233A5 (en) | 1984-05-30 |
JPS53149936A (en) | 1978-12-27 |
AU541144B2 (en) | 1984-12-20 |
IE46886B1 (en) | 1983-10-19 |
DK214878A (en) | 1978-11-18 |
IT7849419A0 (en) | 1978-05-17 |
ES469953A1 (en) | 1979-09-16 |
AU8411782A (en) | 1982-08-26 |
AU523496B2 (en) | 1982-07-29 |
AU3606778A (en) | 1979-11-15 |
FI781490A (en) | 1978-11-18 |
FR2401135B1 (en) | 1983-08-19 |
JPH0112744B2 (en) | 1989-03-02 |
SE443558B (en) | 1986-03-03 |
SE7805591L (en) | 1978-11-18 |
DE2821410A1 (en) | 1978-11-30 |
CH643238A5 (en) | 1984-05-30 |
IE780940L (en) | 1978-11-17 |
FR2398718B1 (en) | 1982-10-15 |
NL7805344A (en) | 1978-11-21 |
IT1156755B (en) | 1987-02-04 |
NZ187235A (en) | 1981-10-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |