IT201800004359A1 - IDENTIFICAZIONE DI miRNA MUSCOLARI COME BIOMARCATORI E TRATTAMENTO CO-ADIUVANTE PER L’ATROFIA MUSCOLARE SPINALE - Google Patents
IDENTIFICAZIONE DI miRNA MUSCOLARI COME BIOMARCATORI E TRATTAMENTO CO-ADIUVANTE PER L’ATROFIA MUSCOLARE SPINALE Download PDFInfo
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- IT201800004359A1 IT201800004359A1 IT102018000004359A IT201800004359A IT201800004359A1 IT 201800004359 A1 IT201800004359 A1 IT 201800004359A1 IT 102018000004359 A IT102018000004359 A IT 102018000004359A IT 201800004359 A IT201800004359 A IT 201800004359A IT 201800004359 A1 IT201800004359 A1 IT 201800004359A1
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- C12N15/09—Recombinant DNA-technology
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- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12N2310/00—Structure or type of the nucleic acid
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| PCT/IB2019/052820 WO2019197954A1 (en) | 2018-04-10 | 2019-04-05 | IDENTIFICATION OF MUSCULAR miRNAS AS MOLECULAR BIOMARKERS AND CO-ADJUVANT FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY |
| EP19722955.2A EP3775212A1 (de) | 2018-04-10 | 2019-04-05 | Identifizierung von muskulären mirnas als molekulare biomarker und co-adjuvans zur behandlung von spinaler muskelatrophie |
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| US20150133522A1 (en) * | 2013-11-11 | 2015-05-14 | Emory University | Manipulating microrna for the management of neurological diseases or conditions and compositions related thereto |
Non-Patent Citations (11)
| Title |
|---|
| CAMERON M. ARMSTRONG ET AL.: "MicroRNA-181a promotes docetaxel resistance in prostate cancer cells", PROSTATE, vol. 77, no. 9, 1 June 2017 (2017-06-01), US, pages 1020 - 1028, XP055532329, ISSN: 0270-4137, DOI: 10.1002/pros.23358 * |
| CREED M. STARY ET AL.: "Inhibition of miR-181a protects female mice from transient focal cerebral ischemia by targeting astrocyte estrogen receptor-[alpha]", MOLECULAR AND CELLULAR NEUROSCIENCE, 1 July 2017 (2017-07-01), United States, pages 118 - 125, XP055532328, Retrieved from the Internet <URL:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561665/> DOI: 10.1016/j.mcn.2017.05.004 * |
| FRANCESCA MAGRI ET AL.: "miRNA in spinal muscular atrophy pathogenesis and therapy", JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 21 November 2017 (2017-11-21), RO, XP055532283, ISSN: 1582-1838, DOI: 10.1111/jcmm.13450 * |
| MIN JEONG KYE ET AL.: "The role of miRNA in motor neuron disease", FRONTIERS IN CELLULAR NEUROSCIENCE, vol. 8, 1 January 2014 (2014-01-01), XP055532352, DOI: 10.3389/fncel.2014.00015 * |
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Also Published As
| Publication number | Publication date |
|---|---|
| EP3775212A1 (de) | 2021-02-17 |
| WO2019197954A1 (en) | 2019-10-17 |
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