IT1392387B1 - Processo per la preparazione di rotigotina - Google Patents
Processo per la preparazione di rotigotinaInfo
- Publication number
- IT1392387B1 IT1392387B1 ITMI2008A001713A ITMI20081713A IT1392387B1 IT 1392387 B1 IT1392387 B1 IT 1392387B1 IT MI2008A001713 A ITMI2008A001713 A IT MI2008A001713A IT MI20081713 A ITMI20081713 A IT MI20081713A IT 1392387 B1 IT1392387 B1 IT 1392387B1
- Authority
- IT
- Italy
- Prior art keywords
- rotigotine
- preparation
- rotigotine preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/08—Hydrogen atoms or radicals containing only hydrogen and carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/34—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
- C07C211/38—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI2008A001713A IT1392387B1 (it) | 2008-09-26 | 2008-09-26 | Processo per la preparazione di rotigotina |
US13/120,682 US8519160B2 (en) | 2008-09-26 | 2009-09-24 | Process for the preparation of rotigotine |
PCT/IB2009/006934 WO2010035111A1 (en) | 2008-09-26 | 2009-09-24 | A process for the preparation of rotigotine |
CA2738392A CA2738392C (en) | 2008-09-26 | 2009-09-24 | Process for the preparation of rotigotine |
EP09752890A EP2331494A1 (en) | 2008-09-26 | 2009-09-24 | A process for the preparation of rotigotine |
US13/948,667 US20130345283A1 (en) | 2008-09-26 | 2013-07-23 | Process for the preparation of rotigotine |
US13/948,633 US20130317255A1 (en) | 2008-09-26 | 2013-07-23 | Process for the preparation of rotigotine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI2008A001713A IT1392387B1 (it) | 2008-09-26 | 2008-09-26 | Processo per la preparazione di rotigotina |
Publications (2)
Publication Number | Publication Date |
---|---|
ITMI20081713A1 ITMI20081713A1 (it) | 2010-03-27 |
IT1392387B1 true IT1392387B1 (it) | 2012-03-02 |
Family
ID=40637856
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI2008A001713A IT1392387B1 (it) | 2008-09-26 | 2008-09-26 | Processo per la preparazione di rotigotina |
Country Status (5)
Country | Link |
---|---|
US (3) | US8519160B2 (it) |
EP (1) | EP2331494A1 (it) |
CA (1) | CA2738392C (it) |
IT (1) | IT1392387B1 (it) |
WO (1) | WO2010035111A1 (it) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102009052972A1 (de) | 2009-11-12 | 2011-09-15 | Lts Lohmann Therapie-Systeme Ag | Verfahren zur Verhinderung der Kristallisation von Arzneistoffen in einem Polymerfilm |
ITMI20111622A1 (it) * | 2011-09-08 | 2013-03-09 | Fidia Farmaceutici | Processo per la preparazione di rotigotina |
US10611749B2 (en) * | 2018-02-15 | 2020-04-07 | Solara Active Pharma Sciences Limited | Process for preparation of Rotigotine and intermediates thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US456428A (en) * | 1891-07-21 | Elevator and conveyer | ||
US4564628A (en) | 1983-01-03 | 1986-01-14 | Nelson Research & Development Co. | Substituted 2-aminotetralins |
CA1338894C (en) * | 1988-01-15 | 1997-02-04 | John Francis De Bernardis | Aminomethyl-chroman and thiochroman compounds as ó-2-adrenergic antagonists |
SE9301732D0 (sv) * | 1993-05-18 | 1993-05-18 | Haakan Wilhelm Wikstroem | New centrally acting 5-,6-,7-, and 8-substituted sulphone esters of n-monosubstituted 2-aminotetralins |
US5382596A (en) * | 1993-08-05 | 1995-01-17 | Whitby Research, Inc. | Substituted 2-aminotetralins |
AU1613101A (en) * | 1999-11-23 | 2001-06-04 | Aderis Pharmaceuticals, Inc. | Improved process for preparing nitrogen-substituted aminotetralins |
-
2008
- 2008-09-26 IT ITMI2008A001713A patent/IT1392387B1/it active
-
2009
- 2009-09-24 EP EP09752890A patent/EP2331494A1/en not_active Withdrawn
- 2009-09-24 US US13/120,682 patent/US8519160B2/en active Active
- 2009-09-24 CA CA2738392A patent/CA2738392C/en active Active
- 2009-09-24 WO PCT/IB2009/006934 patent/WO2010035111A1/en active Application Filing
-
2013
- 2013-07-23 US US13/948,633 patent/US20130317255A1/en not_active Abandoned
- 2013-07-23 US US13/948,667 patent/US20130345283A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2738392C (en) | 2017-06-06 |
US20130317255A1 (en) | 2013-11-28 |
US8519160B2 (en) | 2013-08-27 |
ITMI20081713A1 (it) | 2010-03-27 |
US20130345283A1 (en) | 2013-12-26 |
CA2738392A1 (en) | 2010-04-01 |
WO2010035111A1 (en) | 2010-04-01 |
US20110230541A1 (en) | 2011-09-22 |
EP2331494A1 (en) | 2011-06-15 |
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