IT1293069B1 - Inibitori di nf-kb come attivatori di hsf e induttori di proteine da shock termico - Google Patents

Inibitori di nf-kb come attivatori di hsf e induttori di proteine da shock termico

Info

Publication number
IT1293069B1
IT1293069B1 IT97RM000392A ITRM970392A IT1293069B1 IT 1293069 B1 IT1293069 B1 IT 1293069B1 IT 97RM000392 A IT97RM000392 A IT 97RM000392A IT RM970392 A ITRM970392 A IT RM970392A IT 1293069 B1 IT1293069 B1 IT 1293069B1
Authority
IT
Italy
Prior art keywords
hsf
inductors
activators
inhibitors
protein
Prior art date
Application number
IT97RM000392A
Other languages
English (en)
Italian (it)
Inventor
Maria Gabriella Santoro
Antonio Rossi
Giuliano Elia
Original Assignee
Consiglio Nazionale Ricerche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consiglio Nazionale Ricerche filed Critical Consiglio Nazionale Ricerche
Priority to IT97RM000392A priority Critical patent/IT1293069B1/it
Publication of ITRM970392A0 publication Critical patent/ITRM970392A0/it
Priority to EP98940106A priority patent/EP1003492A2/en
Priority to JP50633999A priority patent/JP2002507981A/ja
Priority to CA002294764A priority patent/CA2294764A1/en
Priority to AU88545/98A priority patent/AU8854598A/en
Priority to PCT/EP1998/004066 priority patent/WO1999001117A2/en
Publication of ITRM970392A1 publication Critical patent/ITRM970392A1/it
Application granted granted Critical
Publication of IT1293069B1 publication Critical patent/IT1293069B1/it
Priority to US10/742,523 priority patent/US20050020687A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Transplantation (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Semiconductor Integrated Circuits (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
IT97RM000392A 1996-01-14 1997-07-01 Inibitori di nf-kb come attivatori di hsf e induttori di proteine da shock termico IT1293069B1 (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT97RM000392A IT1293069B1 (it) 1997-07-01 1997-07-01 Inibitori di nf-kb come attivatori di hsf e induttori di proteine da shock termico
EP98940106A EP1003492A2 (en) 1997-07-01 1998-07-01 Inhibitors of nf-kappab as activators of hsf and inducers of heat shock proteins
JP50633999A JP2002507981A (ja) 1997-07-01 1998-07-01 ＨＳＦ活性化物質および熱ショックタンパク質誘導物質としてのＮＦ−κＢ因子阻害物質
CA002294764A CA2294764A1 (en) 1997-07-01 1998-07-01 Inhibitors of nf-kappab as activators of hsf and inducers of heat shock proteins
AU88545/98A AU8854598A (en) 1997-07-01 1998-07-01 Inhibitors of the nf-(k)b factor as activators of hsf and inducers of heat shockproteins
PCT/EP1998/004066 WO1999001117A2 (en) 1997-07-01 1998-07-01 Inhibitors of nf-kappab as activators of hsf and inducers of heat shock proteins
US10/742,523 US20050020687A1 (en) 1996-01-14 2003-12-19 Methods of treating inflammatory and viral disorders by administering cyclopentenone compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97RM000392A IT1293069B1 (it) 1997-07-01 1997-07-01 Inibitori di nf-kb come attivatori di hsf e induttori di proteine da shock termico

Publications (3)

Publication Number Publication Date
ITRM970392A0 ITRM970392A0 (enrdf_load_stackoverflow) 1997-07-01
ITRM970392A1 ITRM970392A1 (it) 1999-01-01
IT1293069B1 true IT1293069B1 (it) 1999-02-11

Family

ID=11405151

Family Applications (1)

Application Number Title Priority Date Filing Date
IT97RM000392A IT1293069B1 (it) 1996-01-14 1997-07-01 Inibitori di nf-kb come attivatori di hsf e induttori di proteine da shock termico

Country Status (6)

Country Link
EP (1) EP1003492A2 (enrdf_load_stackoverflow)
JP (1) JP2002507981A (enrdf_load_stackoverflow)
AU (1) AU8854598A (enrdf_load_stackoverflow)
CA (1) CA2294764A1 (enrdf_load_stackoverflow)
IT (1) IT1293069B1 (enrdf_load_stackoverflow)
WO (1) WO1999001117A2 (enrdf_load_stackoverflow)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1289250B1 (it) 1996-12-13 1998-09-29 Consiglio Nazionale Ricerche Impiego di 2 ciclopenten 1-one e suoi derivati come inibitori del fattore nf-kb
JP2003089636A (ja) * 2001-07-12 2003-03-28 Hirofumi Kai 熱ショック蛋白質の合成抑制及び機能抑制剤
JP5697879B2 (ja) * 2010-03-12 2015-04-08 株式会社再春館製薬所 熱ショックタンパク質の発現誘導剤
JP2015042675A (ja) * 2014-11-13 2015-03-05 株式会社再春館製薬所 熱ショックタンパク質の発現誘導剤

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4954519A (en) * 1987-04-28 1990-09-04 Georgia Tech Research Corporation Isocoumarins with basic substituents as serine proteases inhibitors, anticoagulants and anti-inflammatory agents
DE4311835A1 (de) * 1993-04-07 1994-10-13 Boehringer Ingelheim Int Verfahren zur Inhibierung der Transkription von Genen

Also Published As

Publication number Publication date
WO1999001117A3 (en) 1999-04-01
EP1003492A2 (en) 2000-05-31
CA2294764A1 (en) 1999-01-14
ITRM970392A0 (enrdf_load_stackoverflow) 1997-07-01
AU8854598A (en) 1999-01-25
WO1999001117A2 (en) 1999-01-14
ITRM970392A1 (it) 1999-01-01
JP2002507981A (ja) 2002-03-12

Similar Documents

Publication Publication Date Title
ATE546139T1 (de) Isoprentransferase proteine inhibitoren
PL331047A1 (en) Novel amidinic derivatives and their application as inhibitors of thrombosin
NO20014535L (no) Inhibitorer av IMPDH-enzym
MA27034A1 (fr) Formulations auto-emulsionnables d'inhibiteurs de la proteine de transfert d'ester de cholesteryle
DE69831755D1 (de) Optoakustische kontrastmittel und anwendungsverfahren
LT98001A (lt) Rotamazės fermento mažos molekulinės masės inhibitoriai
MA26668A1 (fr) ACTIVATEURS DE hPPARy ET hPPARa
PL333505A1 (en) Benzamido-aldehydes and their application as inhibitors of cysteinic proteases
AP9700973A0 (en) Inhibitors of IMPDH enzyme
NO995802L (no) Anvendelse av oljelegemer
IT1277085B1 (it) Composizioni ternarie quasi azeotropiche costituite da fluorocarburi idrogenati e idrocarburi adatte come fluidi refrigeranti
PL337645A1 (en) Novel amidine derivatives and their application as thrombosin inhibitors
NO993717L (no) Anvendelse av gastrointestinale lipase-inhibitorer
PT927183E (pt) Inibidores espirociclicos de metaloproteases
PL335378A1 (en) Derivatives of inverse hydroxamates as metaloprotease inhibitors
DE69831950D1 (de) Inhibitoren des hitzeschock-faktors
ZA983065B (en) Inhibitors of protein farnesyltranferase
ID25848A (id) Komposisi-komposisi dan metode-metode herbisida sinergis
IT1293069B1 (it) Inibitori di nf-kb come attivatori di hsf e induttori di proteine da shock termico
NO994542D0 (no) Organisering av datamaskinbuffer
PL339186A1 (en) Derivatives of pyrrolopyrrolone as inhibitors of neutrophilic elastase
NO20020631D0 (no) Formuleringer for parenteral bruk av estramustinfosfat og albumin
PT882398E (pt) Inibidor de crescimento de thiobacillus thiooxidans
FI974532A0 (fi) Dynamiskt meddelandegraenssnitt
FI971625L (fi) Teräksen lämpökäsittely

Legal Events

Date Code Title Description
0001 Granted