IT1293069B1 - INHIBITORS OF NF-KB AS HSF ACTIVATORS AND PROTEIN INDUCTORS FROM THERMAL SHOCK - Google Patents

INHIBITORS OF NF-KB AS HSF ACTIVATORS AND PROTEIN INDUCTORS FROM THERMAL SHOCK

Info

Publication number
IT1293069B1
IT1293069B1 IT97RM000392A ITRM970392A IT1293069B1 IT 1293069 B1 IT1293069 B1 IT 1293069B1 IT 97RM000392 A IT97RM000392 A IT 97RM000392A IT RM970392 A ITRM970392 A IT RM970392A IT 1293069 B1 IT1293069 B1 IT 1293069B1
Authority
IT
Italy
Prior art keywords
hsf
inductors
activators
inhibitors
protein
Prior art date
Application number
IT97RM000392A
Other languages
Italian (it)
Inventor
Maria Gabriella Santoro
Antonio Rossi
Giuliano Elia
Original Assignee
Consiglio Nazionale Ricerche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consiglio Nazionale Ricerche filed Critical Consiglio Nazionale Ricerche
Priority to IT97RM000392A priority Critical patent/IT1293069B1/en
Publication of ITRM970392A0 publication Critical patent/ITRM970392A0/it
Priority to JP50633999A priority patent/JP2002507981A/en
Priority to PCT/EP1998/004066 priority patent/WO1999001117A2/en
Priority to AU88545/98A priority patent/AU8854598A/en
Priority to CA002294764A priority patent/CA2294764A1/en
Priority to EP98940106A priority patent/EP1003492A2/en
Publication of ITRM970392A1 publication Critical patent/ITRM970392A1/en
Application granted granted Critical
Publication of IT1293069B1 publication Critical patent/IT1293069B1/en
Priority to US10/742,523 priority patent/US20050020687A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Semiconductor Integrated Circuits (AREA)
  • Peptides Or Proteins (AREA)
IT97RM000392A 1996-01-14 1997-07-01 INHIBITORS OF NF-KB AS HSF ACTIVATORS AND PROTEIN INDUCTORS FROM THERMAL SHOCK IT1293069B1 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT97RM000392A IT1293069B1 (en) 1997-07-01 1997-07-01 INHIBITORS OF NF-KB AS HSF ACTIVATORS AND PROTEIN INDUCTORS FROM THERMAL SHOCK
JP50633999A JP2002507981A (en) 1997-07-01 1998-07-01 NF-κB factor inhibitor as HSF activator and heat shock protein inducer
PCT/EP1998/004066 WO1999001117A2 (en) 1997-07-01 1998-07-01 Inhibitors of nf-kappab as activators of hsf and inducers of heat shock proteins
AU88545/98A AU8854598A (en) 1997-07-01 1998-07-01 Inhibitors of the nf-(k)b factor as activators of hsf and inducers of heat shockproteins
CA002294764A CA2294764A1 (en) 1997-07-01 1998-07-01 Inhibitors of nf-kappab as activators of hsf and inducers of heat shock proteins
EP98940106A EP1003492A2 (en) 1997-07-01 1998-07-01 Inhibitors of nf-kappab as activators of hsf and inducers of heat shock proteins
US10/742,523 US20050020687A1 (en) 1996-01-14 2003-12-19 Methods of treating inflammatory and viral disorders by administering cyclopentenone compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97RM000392A IT1293069B1 (en) 1997-07-01 1997-07-01 INHIBITORS OF NF-KB AS HSF ACTIVATORS AND PROTEIN INDUCTORS FROM THERMAL SHOCK

Publications (3)

Publication Number Publication Date
ITRM970392A0 ITRM970392A0 (en) 1997-07-01
ITRM970392A1 ITRM970392A1 (en) 1999-01-01
IT1293069B1 true IT1293069B1 (en) 1999-02-11

Family

ID=11405151

Family Applications (1)

Application Number Title Priority Date Filing Date
IT97RM000392A IT1293069B1 (en) 1996-01-14 1997-07-01 INHIBITORS OF NF-KB AS HSF ACTIVATORS AND PROTEIN INDUCTORS FROM THERMAL SHOCK

Country Status (6)

Country Link
EP (1) EP1003492A2 (en)
JP (1) JP2002507981A (en)
AU (1) AU8854598A (en)
CA (1) CA2294764A1 (en)
IT (1) IT1293069B1 (en)
WO (1) WO1999001117A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1289250B1 (en) 1996-12-13 1998-09-29 Consiglio Nazionale Ricerche USE OF 2 CYCLOPENTEN 1-ONE AND ITS DERIVATIVES AS INHIBITORS OF THE NF-KB FACTOR
JP2003089636A (en) * 2001-07-12 2003-03-28 Hirofumi Kai Agent for suppressing synthesis and function of heat shock protein
JP5697879B2 (en) * 2010-03-12 2015-04-08 株式会社再春館製薬所 Heat shock protein expression inducer
JP2015042675A (en) * 2014-11-13 2015-03-05 株式会社再春館製薬所 Expression inducer for heat shock protein

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4954519A (en) * 1987-04-28 1990-09-04 Georgia Tech Research Corporation Isocoumarins with basic substituents as serine proteases inhibitors, anticoagulants and anti-inflammatory agents
DE4311835A1 (en) * 1993-04-07 1994-10-13 Boehringer Ingelheim Int Method for inhibiting gene transcription

Also Published As

Publication number Publication date
JP2002507981A (en) 2002-03-12
ITRM970392A0 (en) 1997-07-01
ITRM970392A1 (en) 1999-01-01
AU8854598A (en) 1999-01-25
EP1003492A2 (en) 2000-05-31
WO1999001117A2 (en) 1999-01-14
CA2294764A1 (en) 1999-01-14
WO1999001117A3 (en) 1999-04-01

Similar Documents

Publication Publication Date Title
NO20014535L (en) Inhibitors of IMPDH enzyme
MA27034A1 (en) SELF-EMULSIBLE FORMULATIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS
DE69831755D1 (en) OPTOACUSTIC CONSTANCES AND METHOD OF USE
PL331047A1 (en) Novel amidinic derivatives and their application as inhibitors of thrombosin
MA26668A1 (en) ACTIVATORS OF hPPARy AND hPPARa
AP9700973A0 (en) Inhibitors of IMPDH enzyme
PL333505A1 (en) Benzamido-aldehydes and their application as inhibitors of cysteinic proteases
NO995802L (en) Use of oil bodies
IT1277085B1 (en) ALMOST AZEOTROPIC TERNARY COMPOSITIONS CONSISTING OF HYDROGENATED FLUOROCARBONS AND HYDROCARBONS SUITABLE AS REFRIGERANT FLUIDS
PL334846A1 (en) Sulphamidic inhibitors of metaloproteases
PL337645A1 (en) Novel amidine derivatives and their application as thrombosin inhibitors
PT927183E (en) SPIROCYLIC INHIBITORS OF METALOPROTEASES
PL335378A1 (en) Derivatives of inverse hydroxamates as metaloprotease inhibitors
NO993717L (en) Use of gastrointestinal lipase inhibitors
PL339176A1 (en) Derivatives of pyrrolopyrrolone as inhibitors of neutrophilic elastase
AU7933298A (en) Heat shock factor activity inhibitors
ID25848A (en) COMPOSITIONS AND METHODS OF SYNERGIC HERBISIDES
IT1293069B1 (en) INHIBITORS OF NF-KB AS HSF ACTIVATORS AND PROTEIN INDUCTORS FROM THERMAL SHOCK
NO994542D0 (en) Organization of computer buffer
PL339186A1 (en) Derivatives of pyrrolopyrrolone as inhibitors of neutrophilic elastase
ID26703A (en) USE OF LOCAL ANESTHESIA FOR VASCULAR HEADACHE
GB9706652D0 (en) Inhibitors of FPT as anti-inflammatories
NO20020631D0 (en) Formulations for parenteral use of estramustine phosphate and albumin
PT882398E (en) GROWTH INHIBITOR OF THIOBACILLUS THIOOXIDANS
FI974532A0 (en) Dynamic medium of operation

Legal Events

Date Code Title Description
0001 Granted