IT1269214B - PURIFIED FORM OF STREPTOGRAMINE, ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT - Google Patents
PURIFIED FORM OF STREPTOGRAMINE, ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN ITInfo
- Publication number
- IT1269214B IT1269214B ITMI940192A ITMI940192A IT1269214B IT 1269214 B IT1269214 B IT 1269214B IT MI940192 A ITMI940192 A IT MI940192A IT MI940192 A ITMI940192 A IT MI940192A IT 1269214 B IT1269214 B IT 1269214B
- Authority
- IT
- Italy
- Prior art keywords
- radical
- purified form
- streptogramine
- contain
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06182—Dipeptides with the first amino acid being heterocyclic and Pristinamycin II; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Forma purificata di streptogramine costituite da un'associazione di uno o più componenti del gruppo B delle streptgremine, di formula generale (FORMULAI) Nella quale A1 è un radicale di formula generale:in cui R' è H oppure OH e Y è H, un radicale metilamminico, R è un radicale etile oppure, quando R1 è H,R può anche rappresentare - CH3, e R1 e R2 sono H, oppure A1 è radicale di formula: (FORMULA I) R è un radicale isobutile, e R1 è CH e R2 è - CH3, e di uno o più componenti secondari del gruppo A delle streptogramine, di formula generale: (FORMULA I) In cui R'' è H oppure un radicale metile oppure etile, allo stato di cocristallizzato, di coprecipitato oppure di miscela fisica delle polveri.Purified form of streptogramins consisting of an association of one or more components of group B of streptgremins, of general formula (FORMULAI) In which A1 is a radical of general formula: wherein R 'is H or OH and Y is H, a methylamine radical, R is an ethyl radical or, when R1 is H, R can also represent - CH3, and R1 and R2 are H, or A1 is radical of formula: (FORMULA I) R is an isobutyl radical, and R1 is CH and R2 is - CH3, and of one or more secondary components of group A of streptogramins, of general formula: (FORMULA I) wherein R '' is H or a methyl or ethyl radical, in the state of cocrystallized, of co-precipitated or of physical mixture of powders.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9301787A FR2701709B1 (en) | 1993-02-17 | 1993-02-17 | Purified form of streptogramins, its preparation and the pharmaceutical compositions containing it. |
| APAP/P/1994/000660A AP520A (en) | 1993-02-17 | 1994-08-01 | Purified form of streptogramins, its preparation and pharmaceutical compositions containing it. |
| CN94195158A CN1159197A (en) | 1993-02-17 | 1994-08-12 | Purified form of streptogramines, preparation thereof and pharmacueitcal compositions containing it |
| PCT/FR1994/001006 WO1996005219A1 (en) | 1993-02-17 | 1994-08-12 | Purified form of streptogramines, preparation thereof and pharmaceutical compositions containing it |
| OA60964A OA10400A (en) | 1993-02-17 | 1997-02-07 | Purified form of streptogramins its preparation and pharmaceutical compositions containing it |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI940192A0 ITMI940192A0 (en) | 1994-02-03 |
| ITMI940192A1 ITMI940192A1 (en) | 1995-08-03 |
| IT1269214B true IT1269214B (en) | 1997-03-21 |
Family
ID=33437085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI940192A IT1269214B (en) | 1993-02-17 | 1994-02-03 | PURIFIED FORM OF STREPTOGRAMINE, ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPH06298664A (en) |
| AU (1) | AU678785B2 (en) |
| BE (1) | BE1006554A3 (en) |
| BR (1) | BR9408613A (en) |
| CA (1) | CA2115807A1 (en) |
| CZ (1) | CZ285541B6 (en) |
| ES (1) | ES2081763B1 (en) |
| FI (1) | FI111009B (en) |
| FR (1) | FR2701709B1 (en) |
| GB (1) | GB2275269B (en) |
| GR (1) | GR1002385B (en) |
| HU (1) | HUT66821A (en) |
| IL (1) | IL108641A (en) |
| IT (1) | IT1269214B (en) |
| LU (1) | LU88454A1 (en) |
| NO (1) | NO940533D0 (en) |
| NZ (1) | NZ250884A (en) |
| PL (1) | PL174835B1 (en) |
| PT (1) | PT101460B (en) |
| SK (1) | SK18494A3 (en) |
| ZA (1) | ZA941024B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2723373B1 (en) | 1994-08-02 | 1996-09-13 | Rhone Poulenc Rorer Sa | PURIFIED FORM OF STREPTOGRAMINS, ITS PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME |
| FR2841563B1 (en) * | 2002-06-28 | 2006-09-01 | Aventis Pharma Sa | NEW VARIANTS OF THE PAPP POLYPEPTIDE OF BACTERIA GENUS STREPTOMYCES |
| ITUB20169994A1 (en) * | 2016-01-14 | 2017-07-14 | Phf Sa | New crystalline forms of immunomodulatory drugs |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2549065B1 (en) * | 1983-07-13 | 1985-10-25 | Rhone Poulenc Sante | NOVEL SYNERGISTIN DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME |
| FR2619008B1 (en) * | 1987-08-03 | 1990-06-29 | Cird | USE OF SYNERGISTINS IN ANTI-ACNEIC PHARMACEUTICAL OR COSMETIC COMPOSITIONS |
| FR2674539B1 (en) * | 1991-03-28 | 1993-05-21 | Rhone Poulenc Rorer Sa | PROCESS FOR THE ENZYMATIC PREPARATION OF MACROLACTONE. |
| FR2689518B1 (en) * | 1992-04-01 | 1995-04-07 | Rhone Poulenc Rorer Sa | Microorganisms, preparation process and use. |
-
1993
- 1993-02-17 FR FR9301787A patent/FR2701709B1/en not_active Expired - Fee Related
-
1994
- 1994-01-20 LU LU88454A patent/LU88454A1/en unknown
- 1994-02-03 IT ITMI940192A patent/IT1269214B/en active IP Right Grant
- 1994-02-14 PT PT101460A patent/PT101460B/en not_active IP Right Cessation
- 1994-02-14 IL IL10864194A patent/IL108641A/en not_active IP Right Cessation
- 1994-02-14 AU AU55100/94A patent/AU678785B2/en not_active Ceased
- 1994-02-15 ZA ZA941024A patent/ZA941024B/en unknown
- 1994-02-15 SK SK184-94A patent/SK18494A3/en unknown
- 1994-02-15 CZ CZ94326A patent/CZ285541B6/en not_active IP Right Cessation
- 1994-02-15 NZ NZ250884A patent/NZ250884A/en unknown
- 1994-02-15 GR GR940100078A patent/GR1002385B/en not_active IP Right Cessation
- 1994-02-16 FI FI940717A patent/FI111009B/en not_active IP Right Cessation
- 1994-02-16 HU HU9400447A patent/HUT66821A/en unknown
- 1994-02-16 BE BE9400182A patent/BE1006554A3/en not_active IP Right Cessation
- 1994-02-16 CA CA002115807A patent/CA2115807A1/en not_active Abandoned
- 1994-02-16 NO NO940533A patent/NO940533D0/en unknown
- 1994-02-16 JP JP6040579A patent/JPH06298664A/en active Pending
- 1994-02-16 ES ES09400294A patent/ES2081763B1/en not_active Expired - Fee Related
- 1994-02-16 PL PL94302250A patent/PL174835B1/en unknown
- 1994-02-17 GB GB9403057A patent/GB2275269B/en not_active Expired - Fee Related
- 1994-08-12 BR BR9408613A patent/BR9408613A/en not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970225 |