IT1263956B - Procedimento per la preparazione di 5-oxo-2-pirrolidoncarbossilato di piridossina - Google Patents
Procedimento per la preparazione di 5-oxo-2-pirrolidoncarbossilato di piridossinaInfo
- Publication number
- IT1263956B IT1263956B ITMI930340A ITMI930340A IT1263956B IT 1263956 B IT1263956 B IT 1263956B IT MI930340 A ITMI930340 A IT MI930340A IT MI930340 A ITMI930340 A IT MI930340A IT 1263956 B IT1263956 B IT 1263956B
- Authority
- IT
- Italy
- Prior art keywords
- oxo
- preparation
- pyrolidoncarbossilate
- pyridoxy
- procedure
- Prior art date
Links
- -1 PYRIDOXY Chemical class 0.000 title 1
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 abstract 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 2
- 235000008160 pyridoxine Nutrition 0.000 abstract 2
- 239000011677 pyridoxine Substances 0.000 abstract 2
- 229940011671 vitamin b6 Drugs 0.000 abstract 2
- CQYYGCVORGQMEQ-UHFFFAOYSA-N 2,5-dioxopyrrolidine-1-carboxylic acid Chemical compound OC(=O)N1C(=O)CCC1=O CQYYGCVORGQMEQ-UHFFFAOYSA-N 0.000 abstract 1
- ODHCTXKNWHHXJC-VKHMYHEASA-N 5-oxo-L-proline Chemical compound OC(=O)[C@@H]1CCC(=O)N1 ODHCTXKNWHHXJC-VKHMYHEASA-N 0.000 abstract 1
- ODHCTXKNWHHXJC-GSVOUGTGSA-N Pyroglutamic acid Natural products OC(=O)[C@H]1CCC(=O)N1 ODHCTXKNWHHXJC-GSVOUGTGSA-N 0.000 abstract 1
- ODHCTXKNWHHXJC-UHFFFAOYSA-N acide pyroglutamique Natural products OC(=O)C1CCC(=O)N1 ODHCTXKNWHHXJC-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
- C07D213/67—2-Methyl-3-hydroxy-4,5-bis(hydroxy-methyl)pyridine, i.e. pyridoxine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Curing Cements, Concrete, And Artificial Stone (AREA)
- Pyridine Compounds (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI930340A IT1263956B (it) | 1993-02-23 | 1993-02-23 | Procedimento per la preparazione di 5-oxo-2-pirrolidoncarbossilato di piridossina |
| KR1019930005259A KR100257967B1 (ko) | 1993-02-23 | 1993-03-31 | 피리독신 5-옥소-2-피롤리돈 카르복실레이트의 제조공정 |
| TW082104025A TW235962B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-02-23 | 1993-05-21 | |
| AT0900494A AT403160B (de) | 1993-02-23 | 1994-02-19 | Verfahren zur herstellung von pyridoxin 5-oxo-2-pyrrolidoncarboxylat |
| PCT/EP1994/000517 WO1994019324A1 (en) | 1993-02-23 | 1994-02-19 | Process for the preparation of pyridoxine 5-oxo-2-pyrrolidone carboxylate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI930340A IT1263956B (it) | 1993-02-23 | 1993-02-23 | Procedimento per la preparazione di 5-oxo-2-pirrolidoncarbossilato di piridossina |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI930340A0 ITMI930340A0 (it) | 1993-02-23 |
| ITMI930340A1 ITMI930340A1 (it) | 1994-08-23 |
| IT1263956B true IT1263956B (it) | 1996-09-05 |
Family
ID=11365118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI930340A IT1263956B (it) | 1993-02-23 | 1993-02-23 | Procedimento per la preparazione di 5-oxo-2-pirrolidoncarbossilato di piridossina |
Country Status (5)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105906559B (zh) * | 2016-06-14 | 2018-08-14 | 成都倍特药业有限公司 | 一种药用级美他多辛的一步合成法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR6990M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1968-03-13 | 1969-05-27 | ||
| FR2244466A1 (en) * | 1973-06-29 | 1975-04-18 | Dufour Claude | Salts of pyridoxine with aryloxy alkanoic acids - useful as antihyperlipemic agents for oral administration |
| FR2260330A1 (en) * | 1974-02-07 | 1975-09-05 | Innothera Lab Sa | Pyridoxine N-oxy nicotinate - hypolipaemiant and hypocholesterolemiant of good therapeutic index |
| FR2485372B1 (fr) * | 1980-06-30 | 1985-08-09 | Baldacci Lab Spa | Composition pharmaceutique pour le traitement des etats d'intoxication alcoolique aigue a base de 5-oxo-2-pyrrolidone carboxylate de pyridoxine et procede de preparation de ce dernier |
| IT1131856B (it) * | 1980-06-30 | 1986-06-25 | Baldacci Lab Spa | Composizione farmaceutica per il trattamento di intossicazioni alcooliche |
-
1993
- 1993-02-23 IT ITMI930340A patent/IT1263956B/it active IP Right Grant
- 1993-03-31 KR KR1019930005259A patent/KR100257967B1/ko not_active Expired - Fee Related
- 1993-05-21 TW TW082104025A patent/TW235962B/zh not_active IP Right Cessation
-
1994
- 1994-02-19 WO PCT/EP1994/000517 patent/WO1994019324A1/en active Application Filing
- 1994-02-19 AT AT0900494A patent/AT403160B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI930340A1 (it) | 1994-08-23 |
| TW235962B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1994-12-11 |
| WO1994019324A1 (en) | 1994-09-01 |
| AT403160B (de) | 1997-11-25 |
| KR940019703A (ko) | 1994-09-14 |
| KR100257967B1 (ko) | 2000-07-01 |
| ITMI930340A0 (it) | 1993-02-23 |
| ATA900494A (de) | 1997-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970227 |