IT1256299B - Acidi omega-amminoalchiltartronici e loro esteri,procedimento per la loro preparazione e loro uso nella terapia del dismetabolismo osseo - Google Patents
Acidi omega-amminoalchiltartronici e loro esteri,procedimento per la loro preparazione e loro uso nella terapia del dismetabolismo osseoInfo
- Publication number
- IT1256299B IT1256299B ITMI922533A IT1256299B IT 1256299 B IT1256299 B IT 1256299B IT MI922533 A ITMI922533 A IT MI922533A IT 1256299 B IT1256299 B IT 1256299B
- Authority
- IT
- Italy
- Prior art keywords
- alkyl
- phenyl
- aminocarbonyl
- benzyloxycarbonyl
- benzyl
- Prior art date
Links
- ROBFUDYVXSDBQM-UHFFFAOYSA-N hydroxymalonic acid Chemical compound OC(=O)C(O)C(O)=O ROBFUDYVXSDBQM-UHFFFAOYSA-N 0.000 title abstract 4
- 208000001132 Osteoporosis Diseases 0.000 title 1
- 208000011580 syndromic disease Diseases 0.000 title 1
- -1 alkylammonium cation Chemical class 0.000 abstract 12
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 5
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 3
- 125000003088 (fluoren-9-ylmethoxy)carbonyl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
- 125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 abstract 2
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 2
- UYWQUFXKFGHYNT-UHFFFAOYSA-N phenylmethyl ester of formic acid Natural products O=COCC1=CC=CC=C1 UYWQUFXKFGHYNT-UHFFFAOYSA-N 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 125000004848 alkoxyethyl group Chemical group 0.000 abstract 1
- 125000005036 alkoxyphenyl group Chemical group 0.000 abstract 1
- 125000004457 alkyl amino carbonyl group Chemical group 0.000 abstract 1
- 125000000319 biphenyl-4-yl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical group C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 125000003386 piperidinyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- NQRYJNQNLNOLGT-UHFFFAOYSA-N tetrahydropyridine hydrochloride Natural products C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Sono descritti acidi ?-amminoalchiltartronici e loro esteri di formula generale (I) (FORMULA I) dove i sostituenti hanno i significati descritti di seguito, e il loro uso nella terapia del dismetabolismo osseo.
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT002533 IT1256299B (it) | 1992-11-05 | 1992-11-05 | Acidi omega-amminoalchiltartronici e loro esteri,procedimento per la loro preparazione e loro uso nella terapia del dismetabolismo osseo |
DE69311129T DE69311129T2 (de) | 1992-11-05 | 1993-10-25 | Tartronsäure, deren acetalische äther und-o-ester |
AT93923543T ATE153651T1 (de) | 1992-11-05 | 1993-10-25 | Tartronsäure, deren acetalische äther und-o-ester |
US08/424,471 US5656656A (en) | 1992-11-05 | 1993-10-25 | Tartronic acids, their acetalic ethers and O-esters |
JP6510661A JPH08503195A (ja) | 1992-11-05 | 1993-10-25 | タルトロン酸類、それらのアセタリックエーテル類及びo−エステル類 |
CA002148693A CA2148693A1 (en) | 1992-11-05 | 1993-10-25 | Tartronic acids, their acetalic ethers and o-esters |
PCT/EP1993/002941 WO1994010127A1 (en) | 1992-11-05 | 1993-10-25 | Tartronic acids, their acetalic ethers and o-esters |
EP93923543A EP0667850B1 (en) | 1992-11-05 | 1993-10-25 | Tartronic acids, their acetalic ethers and o-esters |
AU53375/94A AU5337594A (en) | 1992-11-05 | 1993-10-25 | Tartronic acids, their acetalic ethers and o-esters |
CN93114397A CN1091741A (zh) | 1992-11-05 | 1993-11-03 | 羟基丙二酸及其缩醛醚和o-酯 |
US08/814,903 US5773465A (en) | 1992-11-05 | 1997-03-12 | Tartronic acids, their acetalic ethers and o-esters |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT002533 IT1256299B (it) | 1992-11-05 | 1992-11-05 | Acidi omega-amminoalchiltartronici e loro esteri,procedimento per la loro preparazione e loro uso nella terapia del dismetabolismo osseo |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI922533A0 ITMI922533A0 (it) | 1992-11-05 |
ITMI922533A1 ITMI922533A1 (it) | 1994-05-05 |
IT1256299B true IT1256299B (it) | 1995-11-29 |
Family
ID=11364233
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT002533 IT1256299B (it) | 1992-11-05 | 1992-11-05 | Acidi omega-amminoalchiltartronici e loro esteri,procedimento per la loro preparazione e loro uso nella terapia del dismetabolismo osseo |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1256299B (it) |
-
1992
- 1992-11-05 IT IT002533 patent/IT1256299B/it active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
ITMI922533A0 (it) | 1992-11-05 |
ITMI922533A1 (it) | 1994-05-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19971126 |