IT1255017B - Vitamina e polietossilata e metodo per la sua preparazione - Google Patents

Vitamina e polietossilata e metodo per la sua preparazione

Info

Publication number
IT1255017B
IT1255017B ITMI920737A ITMI920737A IT1255017B IT 1255017 B IT1255017 B IT 1255017B IT MI920737 A ITMI920737 A IT MI920737A IT MI920737 A ITMI920737 A IT MI920737A IT 1255017 B IT1255017 B IT 1255017B
Authority
IT
Italy
Prior art keywords
vitamin
formula
compound
integer
acetate
Prior art date
Application number
ITMI920737A
Other languages
English (en)
Original Assignee
Pacific Chem Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pacific Chem Co Ltd filed Critical Pacific Chem Co Ltd
Publication of ITMI920737A0 publication Critical patent/ITMI920737A0/it
Publication of ITMI920737A1 publication Critical patent/ITMI920737A1/it
Application granted granted Critical
Publication of IT1255017B publication Critical patent/IT1255017B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/14—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 6 and unsubstituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/26—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
    • C08G65/2603—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen
    • C08G65/2606—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen containing hydroxyl groups
    • C08G65/2612—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen containing hydroxyl groups containing aromatic or arylaliphatic hydroxyl groups
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K23/00—Use of substances as emulsifying, wetting, dispersing, or foam-producing agents
    • C09K23/42—Ethers, e.g. polyglycol ethers of alcohols or phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Polyethers (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)

Abstract

Vitamina E polietossilata di formula (1)(Formula 1) n è un numero intero compreso fra 2 e 100,(Formula 2) m è un numero intero compreso fra 1 e 3.Il composto secondo l'invenzione, che può essere preparato facendo reagire una vitamina E o un suo estere con l'ossido di etilene usando un catalizzatore basico sotto pressione e in condizioni anidre, possiede una stabilità antiossidante e ossidante simile a quella della vitamina E acetato e possiede anche un eccellente effetto di ritenzione dell'umidità ed attività superficiale che la vitamina E e la vitamina E acetato non hanno. Inoltre, il composto é altamente sicuro in vivo.L'invenzione riguarda anche un metodo per la preparazione del composto (1) e i suoi usi.
ITMI920737A 1991-03-29 1992-03-27 Vitamina e polietossilata e metodo per la sua preparazione IT1255017B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR910004991 1991-03-29
KR1019920003360A KR940010888B1 (ko) 1991-03-29 1992-03-02 폴리에톡실레이티드 비타민 e 및 그의 제조방법

Publications (3)

Publication Number Publication Date
ITMI920737A0 ITMI920737A0 (it) 1992-03-27
ITMI920737A1 ITMI920737A1 (it) 1993-09-27
IT1255017B true IT1255017B (it) 1995-10-13

Family

ID=26628545

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI920737A IT1255017B (it) 1991-03-29 1992-03-27 Vitamina e polietossilata e metodo per la sua preparazione

Country Status (9)

Country Link
US (1) US5235073A (it)
JP (1) JP2501267B2 (it)
KR (1) KR940010888B1 (it)
CN (1) CN1037347C (it)
DE (1) DE4210112C2 (it)
FR (1) FR2674525A1 (it)
GB (1) GB2254080B (it)
IT (1) IT1255017B (it)
MY (1) MY108430A (it)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR950007045B1 (ko) * 1992-04-14 1995-06-30 주식회사태평양 폴리에톡실레이티드 비타민 e를 함유한 피부화장료
DE4304303C2 (de) * 1993-01-22 1997-01-30 Pacific Corp Vitamin-E-Derivate mit einem quartären Stickstoffatom, Verfahren zu deren Herstellung und kosmetische Mittel enthaltend dieselben
US5352696A (en) * 1993-01-22 1994-10-04 Pacific Corporation Quaternary nitrogen-containing vitamin E derivatives and uses thereof
KR960016188B1 (ko) * 1993-04-08 1996-12-06 주식회사 태평양 우유를 함유한 수중유(o/w)형 유제의 안정화 방법 및 그의 조성물
KR100195291B1 (ko) * 1997-07-12 1999-06-15 서경배 비이온성 비타민
KR20000000840A (ko) * 1998-06-03 2000-01-15 김영대 신규한 폴리옥시프로필렌폴리옥시에틸렌 비타민 e 및 그의제조방법
US6426362B1 (en) 1999-10-08 2002-07-30 Galileo Laboratories, Inc. Formulations of tocopherols and methods of making and using them
KR20010100224A (ko) * 2000-03-18 2001-11-14 김영대 폴리옥시프로필렌-폴리옥시에틸렌비타민ｅ를 함유하는항산화성 화장료 조성물
KR100356676B1 (ko) * 2000-04-28 2002-10-18 주식회사 태평양 농도 전이형 액정형성화합물 및 이의 제조방법, 및 이를함유하는 화장료 조성물
DE50003908D1 (de) * 2000-08-04 2003-11-06 W Kolb Ag Hedingen Dr Tocopherylalkoxylate, deren Herstellung und Verwendung in kosmetischen und pharmazeutischen Formulierungen
AU2000267372A1 (en) 2000-08-23 2002-03-22 Jisoo Kim Polyoxyethylene-polyoxypropylene vitamin e and process for preparation thereof
US7034054B2 (en) * 2000-12-15 2006-04-25 Galileo Pharmaceuticals, Inc. Methods for the prevention and treatment of cerebral ischemia using non-alpha tocopherols
US20050048126A1 (en) * 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
US7923469B2 (en) 2001-04-30 2011-04-12 Allergen, Inc. Compositions including vitamin-based surfactants and methods for using same
KR100428702B1 (ko) * 2001-05-26 2004-04-28 주식회사 엘지생명과학 폴리에톡실화 알파 토코페롤 에스테르 유도체를 함유하는동물용 사료첨가제 조성물
EP1450787A4 (en) 2001-11-15 2006-01-25 Galileo Pharmaceuticals Inc FORMULATIONS AND METHODS FOR THE TREATMENT OR AMELIORATION OF INFLAMMATORY CONDITIONS
US20060165769A1 (en) * 2004-09-30 2006-07-27 Hyatt John A Pharmaceutical formulations containing vitamin E TPGS molecules that solubilize lipophilic drugs without significant efflux inhibition, and use of such formulations
JP2008156326A (ja) 2006-12-26 2008-07-10 Shiseido Co Ltd 化粧料
JP5502261B2 (ja) * 2006-12-26 2014-05-28 日本乳化剤株式会社 両親媒性ビタミンｅ誘導体
JP5263940B2 (ja) * 2008-05-29 2013-08-14 株式会社 資生堂 皮膚外用剤
RU2467005C1 (ru) * 2011-07-15 2012-11-20 Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") СПОСОБ ПОЛУЧЕНИЯ ПОЛИАЛКИЛЕНГЛИКОЛЕВЫХ ЭФИРОВ α-ТОКОФЕРОЛА
US9040034B2 (en) 2013-04-09 2015-05-26 International Business Machines Corporation Vitamin functionalized gel-forming block copolymers for biomedical applications
CN107569398B (zh) * 2017-09-01 2020-06-26 拉芳家化股份有限公司 一种含奶的水包油乳液
CN115698128A (zh) * 2020-06-05 2023-02-03 巴斯夫欧洲公司 基于生育酚的非离子和阴离子表面活性剂

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0026546B1 (en) * 1979-09-27 1985-09-04 Union Carbide Corporation Process for reaction of epoxides with organic compounds having an active hydrogen
CA1185993A (en) * 1981-12-23 1985-04-23 Shell Canada Limited Process for preparing alkanol alkoxylates
AU552988B2 (en) * 1982-03-31 1986-06-26 Shell Internationale Research Maatschappij B.V. Polymerizing epoxides and catalyst suspensions for this

Also Published As

Publication number Publication date
JP2501267B2 (ja) 1996-05-29
DE4210112A1 (de) 1992-10-01
KR940010888B1 (ko) 1994-11-19
US5235073A (en) 1993-08-10
CN1065458A (zh) 1992-10-21
FR2674525A1 (fr) 1992-10-02
MY108430A (en) 1996-09-30
GB2254080B (en) 1994-08-17
GB9205379D0 (en) 1992-04-22
DE4210112C2 (de) 1996-09-19
ITMI920737A1 (it) 1993-09-27
FR2674525B1 (it) 1995-05-12
ITMI920737A0 (it) 1992-03-27
GB2254080A (en) 1992-09-30
KR920018041A (ko) 1992-10-21
CN1037347C (zh) 1998-02-11
JPH05194474A (ja) 1993-08-03

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Legal Events

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0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970326