IT1247827B - Benzoil carbinolo e suoi esteri, utili come inibitori dell'angiogenesi - Google Patents

Benzoil carbinolo e suoi esteri, utili come inibitori dell'angiogenesi

Info

Publication number
IT1247827B
IT1247827B ITMI910276A ITMI910276A IT1247827B IT 1247827 B IT1247827 B IT 1247827B IT MI910276 A ITMI910276 A IT MI910276A IT MI910276 A ITMI910276 A IT MI910276A IT 1247827 B IT1247827 B IT 1247827B
Authority
IT
Italy
Prior art keywords
esters
carbinol
benzoil
useful
angiogenic inhibitors
Prior art date
Application number
ITMI910276A
Other languages
English (en)
Italian (it)
Inventor
Nicola Mongelli
Maria Grandi
Marina Ciomei
Enrico Pesenti
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Priority to ITMI910276A priority Critical patent/IT1247827B/it
Publication of ITMI910276A0 publication Critical patent/ITMI910276A0/it
Priority to GB9202311A priority patent/GB2252498B/en
Priority to DE4203116A priority patent/DE4203116A1/de
Priority to JP4019133A priority patent/JPH04338328A/ja
Publication of ITMI910276A1 publication Critical patent/ITMI910276A1/it
Application granted granted Critical
Publication of IT1247827B publication Critical patent/IT1247827B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ITMI910276A 1991-02-05 1991-02-05 Benzoil carbinolo e suoi esteri, utili come inibitori dell'angiogenesi IT1247827B (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ITMI910276A IT1247827B (it) 1991-02-05 1991-02-05 Benzoil carbinolo e suoi esteri, utili come inibitori dell'angiogenesi
GB9202311A GB2252498B (en) 1991-02-05 1992-02-04 Benzoyl carbinol and its esters,useful as inhibitors of angiogenesis
DE4203116A DE4203116A1 (de) 1991-02-05 1992-02-04 Benzoylcarbinol und dessen ester, geeignet als inhibitoren der gefaessbildung
JP4019133A JPH04338328A (ja) 1991-02-05 1992-02-04 血管形成阻害剤として有用なベンゾイルカルビノール及びそのエステル

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI910276A IT1247827B (it) 1991-02-05 1991-02-05 Benzoil carbinolo e suoi esteri, utili come inibitori dell'angiogenesi

Publications (3)

Publication Number Publication Date
ITMI910276A0 ITMI910276A0 (it) 1991-02-05
ITMI910276A1 ITMI910276A1 (it) 1992-08-05
IT1247827B true IT1247827B (it) 1995-01-02

Family

ID=11358413

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI910276A IT1247827B (it) 1991-02-05 1991-02-05 Benzoil carbinolo e suoi esteri, utili come inibitori dell'angiogenesi

Country Status (4)

Country Link
JP (1) JPH04338328A (de)
DE (1) DE4203116A1 (de)
GB (1) GB2252498B (de)
IT (1) IT1247827B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6908910B2 (en) 1993-08-06 2005-06-21 The Children's Medical Center Corporation Estrogenic compounds as anti-mitotic agents
US5504074A (en) 1993-08-06 1996-04-02 Children's Medical Center Corporation Estrogenic compounds as anti-angiogenic agents
US6346510B1 (en) 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
KR19990082639A (ko) * 1996-02-19 1999-11-25 미즈노 마사루 당뇨병 치료제
US7087592B1 (en) 1999-08-23 2006-08-08 Entre Med, Inc. Compositions comprising purified 2-methoxyestradiol and methods of producing same
CA2558014A1 (en) 2004-03-12 2005-09-29 Entremed, Inc. Antiangiogenic agents
CA2646065C (en) 2006-03-20 2014-01-14 Entremed, Inc. Disease modifying anti-arthritic activity of 2-methoxyestradiol
CN115974758A (zh) * 2022-12-14 2023-04-18 生物岛实验室 羧甲基酮类化合物及其制备方法

Also Published As

Publication number Publication date
JPH04338328A (ja) 1992-11-25
GB9202311D0 (en) 1992-03-18
ITMI910276A0 (it) 1991-02-05
GB2252498B (en) 1994-09-14
GB2252498A (en) 1992-08-12
DE4203116A1 (de) 1992-08-06
ITMI910276A1 (it) 1992-08-05

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960126