IT1237204B - Procedimento per la preparazione di 2-aril-3-idrossi-cis-2,3-diidro- 1,5-benzotiazepin-4(5h)-oni e derivati - Google Patents

Procedimento per la preparazione di 2-aril-3-idrossi-cis-2,3-diidro- 1,5-benzotiazepin-4(5h)-oni e derivati

Info

Publication number
IT1237204B
IT1237204B IT02249789A IT2249789A IT1237204B IT 1237204 B IT1237204 B IT 1237204B IT 02249789 A IT02249789 A IT 02249789A IT 2249789 A IT2249789 A IT 2249789A IT 1237204 B IT1237204 B IT 1237204B
Authority
IT
Italy
Prior art keywords
benzothiazepin
aril
dihydro
cis
hydroxy
Prior art date
Application number
IT02249789A
Other languages
English (en)
Other versions
IT8922497A0 (it
Inventor
Amleto Rizzi
Gaetano Marchioro
Original Assignee
F I S Fabbrica Italiana Sint
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F I S Fabbrica Italiana Sint filed Critical F I S Fabbrica Italiana Sint
Priority to IT02249789A priority Critical patent/IT1237204B/it
Publication of IT8922497A0 publication Critical patent/IT8922497A0/it
Priority to US07/615,687 priority patent/US5128468A/en
Priority to CA002030374A priority patent/CA2030374A1/en
Application granted granted Critical
Publication of IT1237204B publication Critical patent/IT1237204B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
IT02249789A 1989-11-23 1989-11-23 Procedimento per la preparazione di 2-aril-3-idrossi-cis-2,3-diidro- 1,5-benzotiazepin-4(5h)-oni e derivati IT1237204B (it)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IT02249789A IT1237204B (it) 1989-11-23 1989-11-23 Procedimento per la preparazione di 2-aril-3-idrossi-cis-2,3-diidro- 1,5-benzotiazepin-4(5h)-oni e derivati
US07/615,687 US5128468A (en) 1989-11-23 1990-11-19 Process for preparing 2-aryl-3-hydroxy-cis-2,3-dihydro-1,5-benzothiazepin-4(5H)-ones and their derivatives
CA002030374A CA2030374A1 (en) 1989-11-23 1990-11-20 Process for preparing 2-aryl-3-hydroxy-cis-2,3-dihydro-1,5-benzothiazepin-4(5h)-o nes and their derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02249789A IT1237204B (it) 1989-11-23 1989-11-23 Procedimento per la preparazione di 2-aril-3-idrossi-cis-2,3-diidro- 1,5-benzotiazepin-4(5h)-oni e derivati

Publications (2)

Publication Number Publication Date
IT8922497A0 IT8922497A0 (it) 1989-11-23
IT1237204B true IT1237204B (it) 1993-05-26

Family

ID=11197071

Family Applications (1)

Application Number Title Priority Date Filing Date
IT02249789A IT1237204B (it) 1989-11-23 1989-11-23 Procedimento per la preparazione di 2-aril-3-idrossi-cis-2,3-diidro- 1,5-benzotiazepin-4(5h)-oni e derivati

Country Status (3)

Country Link
US (1) US5128468A (it)
CA (1) CA2030374A1 (it)
IT (1) IT1237204B (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001025267A2 (en) * 1999-10-04 2001-04-12 Twinstrand Therapeutics Inc. Improved ricin-like toxins for treatment of cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4590188A (en) * 1984-02-18 1986-05-20 Tanabe Seiyaku Co., Ltd. 1,5-benzothiazepine derivatives and their pharmaceutical use
US5008433A (en) * 1988-05-18 1991-04-16 Marion Laboratories, Inc. 2-hydroxy-3-(4-methoxyphenyl)-3-(2-aminophenylthio)propionic acid, 8'-phenylmenthyl ester, especially for diltiazem
US5008411A (en) * 1988-05-24 1991-04-16 Hoffmann-La Roche Inc. Glycidic acid ester and process of preparation

Also Published As

Publication number Publication date
US5128468A (en) 1992-07-07
CA2030374A1 (en) 1991-05-24
IT8922497A0 (it) 1989-11-23

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19961127