IT1226794B - Derivati della benzazepina quali agenti cardiovascolari. - Google Patents

Derivati della benzazepina quali agenti cardiovascolari.

Info

Publication number
IT1226794B
IT1226794B IT8821365A IT2136588A IT1226794B IT 1226794 B IT1226794 B IT 1226794B IT 8821365 A IT8821365 A IT 8821365A IT 2136588 A IT2136588 A IT 2136588A IT 1226794 B IT1226794 B IT 1226794B
Authority
IT
Italy
Prior art keywords
benzazepin
derivatives
cardiovascular agents
cardiovascular
agents
Prior art date
Application number
IT8821365A
Other languages
English (en)
Other versions
IT8821365A0 (it
Inventor
Jagabandhu Das
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT8821365A0 publication Critical patent/IT8821365A0/it
Application granted granted Critical
Publication of IT1226794B publication Critical patent/IT1226794B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT8821365A 1987-07-27 1988-07-14 Derivati della benzazepina quali agenti cardiovascolari. IT1226794B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/078,319 US4771047A (en) 1987-07-27 1987-07-27 Benzazepine derivatives

Publications (2)

Publication Number Publication Date
IT8821365A0 IT8821365A0 (it) 1988-07-14
IT1226794B true IT1226794B (it) 1991-02-19

Family

ID=22143281

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8821365A IT1226794B (it) 1987-07-27 1988-07-14 Derivati della benzazepina quali agenti cardiovascolari.

Country Status (7)

Country Link
US (1) US4771047A (it)
JP (1) JPS6440462A (it)
CA (1) CA1319365C (it)
DE (1) DE3825368A1 (it)
FR (1) FR2618777B1 (it)
GB (1) GB2207427B (it)
IT (1) IT1226794B (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5559017A (en) * 1989-08-09 1996-09-24 E. R. Squibb & Sons, Inc. Microbial reduction of benzazepines and benzothiazepine derivatives
WO1995004534A1 (en) * 1993-08-06 1995-02-16 Smithkline Beecham Corporation Endothelin receptor antagonists
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
WO2006116718A2 (en) 2005-04-28 2006-11-02 Proteus Biomedical, Inc. Pharma-informatics system
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質(rap)結合体の投与による肝障害の処置
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
EA024559B1 (ru) 2009-05-06 2016-09-30 Лаборэтори Скин Кэа, Инк. Композиции для нанесения на кератинизированную поверхность кожи млекопитающего и способ доставки
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
JP2022055368A (ja) * 2019-02-19 2022-04-08 株式会社三和化学研究所 ベンゾアゼピン誘導体の製造方法及びその中間体

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3312691A (en) * 1963-08-23 1967-04-04 Ciba Geigy Corp 2, 3, 4, 5-tetrahydro-1-benzazepin-2-ones
US3330823A (en) * 1964-12-16 1967-07-11 Squibb & Sons Inc N-amino-loweralkylene-benzo-lactams
US3395150A (en) * 1965-02-26 1968-07-30 Squibb & Sons Inc Benzothiazepine carboxamides and derivatives thereof
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
CA1271747A (en) * 1985-06-12 1990-07-17 David M. Floyd Benzazepines derivatives
CA1271748A (en) * 1985-12-12 1990-07-17 Jagabandhu Das Benzazepine derivatives

Also Published As

Publication number Publication date
GB2207427B (en) 1991-04-03
JPS6440462A (en) 1989-02-10
FR2618777A1 (fr) 1989-02-03
CA1319365C (en) 1993-06-22
DE3825368A1 (de) 1989-02-09
FR2618777B1 (fr) 1992-05-29
US4771047A (en) 1988-09-13
GB2207427A (en) 1989-02-01
IT8821365A0 (it) 1988-07-14
GB8817798D0 (en) 1988-09-01

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940726