IT1222707B - Analoghi di 7-ossabiciclo (2.2.1) eptano utili quali inibitori di 5-lipossigenasi e cicloosigenasi - Google Patents

Analoghi di 7-ossabiciclo (2.2.1) eptano utili quali inibitori di 5-lipossigenasi e cicloosigenasi

Info

Publication number
IT1222707B
IT1222707B IT21996/87A IT2199687A IT1222707B IT 1222707 B IT1222707 B IT 1222707B IT 21996/87 A IT21996/87 A IT 21996/87A IT 2199687 A IT2199687 A IT 2199687A IT 1222707 B IT1222707 B IT 1222707B
Authority
IT
Italy
Prior art keywords
oxybicycle
cycloosygenase
lipoxygenase
heptane
analogs
Prior art date
Application number
IT21996/87A
Other languages
English (en)
Other versions
IT8721996A0 (it
Inventor
Ravi K Varma
Eric M Gordon
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT8721996A0 publication Critical patent/IT8721996A0/it
Application granted granted Critical
Publication of IT1222707B publication Critical patent/IT1222707B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT21996/87A 1986-09-23 1987-09-23 Analoghi di 7-ossabiciclo (2.2.1) eptano utili quali inibitori di 5-lipossigenasi e cicloosigenasi IT1222707B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/910,583 US4695585A (en) 1986-09-23 1986-09-23 7-oxabicyclo(2.2.1)heptane analogs useful as inhibitors of 5-lipoxygenase and cyclooxygenase

Publications (2)

Publication Number Publication Date
IT8721996A0 IT8721996A0 (it) 1987-09-23
IT1222707B true IT1222707B (it) 1990-09-12

Family

ID=25429021

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21996/87A IT1222707B (it) 1986-09-23 1987-09-23 Analoghi di 7-ossabiciclo (2.2.1) eptano utili quali inibitori di 5-lipossigenasi e cicloosigenasi

Country Status (7)

Country Link
US (1) US4695585A (it)
JP (1) JPS6393786A (it)
CA (1) CA1296344C (it)
DE (1) DE3731855A1 (it)
FR (1) FR2604175B1 (it)
GB (1) GB2196000B (it)
IT (1) IT1222707B (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101357438B1 (ko) 2009-04-29 2014-02-06 아마린 코포레이션 피엘씨 Ｅｐａ 및 심혈관 제제를 포함하는 제약 조성물 및 그의 사용 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
US4254044A (en) * 1977-11-04 1981-03-03 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds
JPS58113152A (ja) * 1981-12-28 1983-07-05 Ono Pharmaceut Co Ltd ２−アミノフエノ−ル誘導体、その製造方法およびそれらを有効成分として含有する治療剤
US4582854A (en) * 1983-03-14 1986-04-15 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted oxa prostaglandin analgos useful in the treatment of thrombolytic disease
US4522949A (en) * 1983-10-20 1985-06-11 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted prostaglandin interphenylene analogs useful as cardiovascular agents
US4536513A (en) * 1984-03-14 1985-08-20 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted prostaglandin interphenylene analogs useful in the treatment of thrombolytic disease

Also Published As

Publication number Publication date
JPS6393786A (ja) 1988-04-25
GB2196000A (en) 1988-04-20
DE3731855A1 (de) 1988-03-31
US4695585A (en) 1987-09-22
IT8721996A0 (it) 1987-09-23
GB8720383D0 (en) 1987-10-07
CA1296344C (en) 1992-02-25
GB2196000B (en) 1990-06-13
FR2604175B1 (fr) 1991-10-04
FR2604175A1 (fr) 1988-03-25

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940930