IT1210849B - Derivati tiolici dell'eritromicina ad attivita' terapeutica, relativo procedimento di preparazione e composizioni farmaceutiche che licontengono. - Google Patents
Derivati tiolici dell'eritromicina ad attivita' terapeutica, relativo procedimento di preparazione e composizioni farmaceutiche che licontengono.Info
- Publication number
- IT1210849B IT1210849B IT8219410A IT1941082A IT1210849B IT 1210849 B IT1210849 B IT 1210849B IT 8219410 A IT8219410 A IT 8219410A IT 1941082 A IT1941082 A IT 1941082A IT 1210849 B IT1210849 B IT 1210849B
- Authority
- IT
- Italy
- Prior art keywords
- erythromycin
- propionic ester
- salts
- cooh
- acid
- Prior art date
Links
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title abstract 12
- 229960003276 erythromycin Drugs 0.000 title abstract 6
- 150000003839 salts Chemical class 0.000 title abstract 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical class CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 title 1
- FKRCODPIKNYEAC-UHFFFAOYSA-N ethyl propionate Chemical compound CCOC(=O)CC FKRCODPIKNYEAC-UHFFFAOYSA-N 0.000 abstract 3
- 150000003573 thiols Chemical class 0.000 abstract 2
- JJVXHDTWVIPRBZ-VKHMYHEASA-N (2r)-2-[carboxy(methyl)amino]-3-sulfanylpropanoic acid Chemical compound OC(=O)N(C)[C@@H](CS)C(O)=O JJVXHDTWVIPRBZ-VKHMYHEASA-N 0.000 abstract 1
- DZLNHFMRPBPULJ-VKHMYHEASA-N L-thioproline Chemical compound OC(=O)[C@@H]1CSCN1 DZLNHFMRPBPULJ-VKHMYHEASA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000000443 aerosol Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000003172 expectorant agent Substances 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 229940066491 mucolytics Drugs 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- -1 propionyl ester Chemical class 0.000 abstract 1
- NJRXVEJTAYWCQJ-UHFFFAOYSA-N thiomalic acid Chemical compound OC(=O)CC(S)C(O)=O NJRXVEJTAYWCQJ-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8101930A FR2502627A1 (fr) | 1981-02-02 | 1981-02-02 | Derives thioliques de l'erythromycine a activite therapeutique, procede de preparation et produits pharmaceutiques dans lesquels ils apparaissent |
| FR8200821A FR2519988B1 (fr) | 1982-01-20 | 1982-01-20 | Derives thioliques de l'erythromycine a activite therapeutique, procede de preparation et produits pharmaceutiques dans lesquels ils apparaissent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8219410A0 IT8219410A0 (it) | 1982-02-02 |
| IT1210849B true IT1210849B (it) | 1989-09-29 |
Family
ID=26222205
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8219410A IT1210849B (it) | 1981-02-02 | 1982-02-02 | Derivati tiolici dell'eritromicina ad attivita' terapeutica, relativo procedimento di preparazione e composizioni farmaceutiche che licontengono. |
| IT8421319A IT1227789B (it) | 1981-02-02 | 1984-06-08 | Derivati tiolici dell'eritromicina ad attivita' terapeutica, relativo procedimento di preparazione e composizioni farmaceutiche che li contengono. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8421319A IT1227789B (it) | 1981-02-02 | 1984-06-08 | Derivati tiolici dell'eritromicina ad attivita' terapeutica, relativo procedimento di preparazione e composizioni farmaceutiche che li contengono. |
Country Status (1)
| Country | Link |
|---|---|
| IT (2) | IT1210849B (it) |
-
1982
- 1982-02-02 IT IT8219410A patent/IT1210849B/it active
-
1984
- 1984-06-08 IT IT8421319A patent/IT1227789B/it active Protection Beyond IP Right Term
Also Published As
| Publication number | Publication date |
|---|---|
| IT8421319A0 (it) | 1984-06-08 |
| IT8219410A0 (it) | 1982-02-02 |
| IT1227789B (it) | 1991-05-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970227 |