IT1202787B - Isocromani,isotiocromani,2-benzossepine e 2-benzotiepine,composizioni farmaceutiche che li contengono e loro impiego come agenti ipotensivi e agenti antipsicotici - Google Patents

Isocromani,isotiocromani,2-benzossepine e 2-benzotiepine,composizioni farmaceutiche che li contengono e loro impiego come agenti ipotensivi e agenti antipsicotici

Info

Publication number
IT1202787B
IT1202787B IT29117/78A IT2911778A IT1202787B IT 1202787 B IT1202787 B IT 1202787B IT 29117/78 A IT29117/78 A IT 29117/78A IT 2911778 A IT2911778 A IT 2911778A IT 1202787 B IT1202787 B IT 1202787B
Authority
IT
Italy
Prior art keywords
agents
isothiochromans
isocromans
hypothensive
benzossepine
Prior art date
Application number
IT29117/78A
Other languages
English (en)
Other versions
IT7829117A0 (it
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of IT7829117A0 publication Critical patent/IT7829117A0/it
Application granted granted Critical
Publication of IT1202787B publication Critical patent/IT1202787B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/76—Benzo[c]pyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
IT29117/78A 1977-10-31 1978-10-25 Isocromani,isotiocromani,2-benzossepine e 2-benzotiepine,composizioni farmaceutiche che li contengono e loro impiego come agenti ipotensivi e agenti antipsicotici IT1202787B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84735077A 1977-10-31 1977-10-31

Publications (2)

Publication Number Publication Date
IT7829117A0 IT7829117A0 (it) 1978-10-25
IT1202787B true IT1202787B (it) 1989-02-09

Family

ID=25300400

Family Applications (1)

Application Number Title Priority Date Filing Date
IT29117/78A IT1202787B (it) 1977-10-31 1978-10-25 Isocromani,isotiocromani,2-benzossepine e 2-benzotiepine,composizioni farmaceutiche che li contengono e loro impiego come agenti ipotensivi e agenti antipsicotici

Country Status (11)

Country Link
US (1) US4153612A (it)
JP (1) JPS5481287A (it)
AU (1) AU521752B2 (it)
BE (1) BE871702A (it)
CH (1) CH645371A5 (it)
DE (1) DE2846043A1 (it)
FR (1) FR2407212A1 (it)
GB (1) GB2007216B (it)
IT (1) IT1202787B (it)
NL (1) NL7810820A (it)
ZA (1) ZA785699B (it)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207239A (en) * 1977-10-31 1980-06-10 The Upjohn Company Benzothiepins
US4206123A (en) * 1977-10-31 1980-06-03 Mccall John M Isothiochroman
US4556656A (en) * 1978-10-23 1985-12-03 The Upjohn Company 2-Benzoxepins
DE2931399A1 (de) * 1979-08-02 1981-02-26 Kali Chemie Pharma Gmbh Neue 3-amino-1-benzoxepin-derivate und ihre salze, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
DE2931398A1 (de) * 1979-08-02 1981-02-26 Kali Chemie Pharma Gmbh Neue 1-benzoxepin-5(2h)-on-derivate und ihre salze, verfahren und zwischenprodukte zu deren herstellung und diese verbindungen enthaltende arzneimittel
US5120843A (en) * 1987-04-27 1992-06-09 Upjohn Pharmaceutically active amines
US4963568A (en) * 1989-05-31 1990-10-16 Abbott Laboratories Dopamine agonists
DE4140540A1 (de) * 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
CA2176722A1 (en) * 1993-12-28 1995-07-06 Ruth E. Ten Brink Heterocyclic compounds for the treatment of cns and cardiovascular disorders
WO1996038435A1 (en) * 1995-05-30 1996-12-05 Abbott Laboratories Dopamine agonists
US6004982A (en) * 1997-09-15 1999-12-21 Hoechst Marion Roussel, Inc. 4-piperidinyl) H-2-benzopyran derivatives useful as antipsychotic agents
US6221897B1 (en) * 1998-06-10 2001-04-24 Aventis Pharma Deutschland Gmbh Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
US7632861B2 (en) * 2007-11-13 2009-12-15 Bristol-Myers Squibb Company Substituted heterocyclic ethers and their use in CNS disorders
KR102051030B1 (ko) 2011-10-28 2019-12-02 루메나 파마수티컬즈, 인코포레이티드 소아 담즙울체성 간 질환 치료용 담즙산 재순환 억제제
CN115677719A (zh) * 2022-10-27 2023-02-03 复旦大学 一种芳基并杂环化合物及其制备方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143702A (it) * 1965-03-18
JPS51125287A (en) * 1974-12-04 1976-11-01 Takeda Chem Ind Ltd Aprocess for preparing heterocyclic compounds
JPS5919549B2 (ja) * 1976-01-01 1984-05-07 武田薬品工業株式会社 異節環状化合物

Also Published As

Publication number Publication date
BE871702A (fr) 1979-04-30
NL7810820A (nl) 1979-05-02
FR2407212B1 (it) 1983-02-25
IT7829117A0 (it) 1978-10-25
CH645371A5 (de) 1984-09-28
AU4061578A (en) 1980-04-17
DE2846043A1 (de) 1979-05-03
US4153612A (en) 1979-05-08
ZA785699B (en) 1980-05-28
AU521752B2 (en) 1982-04-29
FR2407212A1 (fr) 1979-05-25
GB2007216B (en) 1982-09-08
GB2007216A (en) 1979-05-16
JPS5481287A (en) 1979-06-28

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