IT1176632B - Analoghi di prostaglandine di tiocarbammati 7-ossabicicloeptano sostituiti - Google Patents

Analoghi di prostaglandine di tiocarbammati 7-ossabicicloeptano sostituiti

Info

Publication number
IT1176632B
IT1176632B IT22419/84A IT2241984A IT1176632B IT 1176632 B IT1176632 B IT 1176632B IT 22419/84 A IT22419/84 A IT 22419/84A IT 2241984 A IT2241984 A IT 2241984A IT 1176632 B IT1176632 B IT 1176632B
Authority
IT
Italy
Prior art keywords
oxabicycleptane
thiocarbamates
replaced
prostaglandin analogs
prostaglandin
Prior art date
Application number
IT22419/84A
Other languages
English (en)
Other versions
IT8422419A0 (it
Inventor
Das Jagabandhu
Martin F Haslanger
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT8422419A0 publication Critical patent/IT8422419A0/it
Application granted granted Critical
Publication of IT1176632B publication Critical patent/IT1176632B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IT22419/84A 1983-08-29 1984-08-24 Analoghi di prostaglandine di tiocarbammati 7-ossabicicloeptano sostituiti IT1176632B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/527,070 US4525479A (en) 1983-08-29 1983-08-29 7-Oxabicycloheptane substituted thiocarbamate prostaglandin analogs useful as cardiovascular agents

Publications (2)

Publication Number Publication Date
IT8422419A0 IT8422419A0 (it) 1984-08-24
IT1176632B true IT1176632B (it) 1987-08-18

Family

ID=24099976

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22419/84A IT1176632B (it) 1983-08-29 1984-08-24 Analoghi di prostaglandine di tiocarbammati 7-ossabicicloeptano sostituiti

Country Status (6)

Country Link
US (1) US4525479A (it)
JP (1) JPS6072879A (it)
DE (1) DE3431479A1 (it)
FR (1) FR2551065A1 (it)
GB (1) GB2145715A (it)
IT (1) IT1176632B (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4654355A (en) * 1985-08-01 1987-03-31 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted amide-thioamide prostaglandin analogs
US4738978A (en) * 1986-11-10 1988-04-19 E. R. Squibb & Sons, Inc. Bisthioamide-7-oxabicycloheptane prostaglandin analogs
US6866797B1 (en) 2000-08-03 2005-03-15 Bj Services Company Corrosion inhibitors and methods of use
US20030129186A1 (en) 2001-07-25 2003-07-10 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
SI1889198T1 (sl) 2005-04-28 2015-02-27 Proteus Digital Health, Inc. Farma-informacijski sistem
EP2063905B1 (en) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
DK2398500T3 (da) 2009-02-20 2019-05-13 2 Bbb Medicines B V Glutathion-baseret lægemiddelafgivelsessystem
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2235927A1 (en) * 1973-06-25 1975-01-31 Aries Robert Carbamate esters of prostaglandins - with stronger or prolonged activity similar to parent prostaglandins
US4220594A (en) * 1977-11-04 1980-09-02 E. R. Squibb & Sons, Inc. Hexa- and octahydro-4,7-epoxyisobenzofuran-1-ol and hexa- and octahydro-5,8-epoxy-1H-2-benzopyran-3-ol
US4187236A (en) * 1977-11-04 1980-02-05 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane compounds
US4254044A (en) * 1977-11-04 1981-03-03 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
EP0013607B1 (en) * 1979-01-05 1983-03-23 National Research Development Corporation Substituted bicyclo (2,2,1)heptanes and bicyclo (2,2,1) hept-2-enes and their pharmaceutical compositions
JPS5931504B2 (ja) * 1979-09-21 1984-08-02 東レ株式会社 新規なプロスタグランジン誘導体
US4228180A (en) * 1979-11-01 1980-10-14 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs
ZA814307B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
US4466979A (en) * 1983-01-21 1984-08-21 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted carbamate prostaglandin analogs useful in treating platelet aggregation and bronchoconstriction

Also Published As

Publication number Publication date
GB2145715A (en) 1985-04-03
IT8422419A0 (it) 1984-08-24
US4525479A (en) 1985-06-25
FR2551065A1 (fr) 1985-03-01
GB8420815D0 (en) 1984-09-19
JPS6072879A (ja) 1985-04-24
DE3431479A1 (de) 1985-03-07

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