IT1172129B - PHENYLALKYLAMIN COMPOUNDS EQUIPPED WITH PHARMACOLOGICAL ACTIVITIES IN PARTICULAR ON THE HEART AND ON THE CIRCULATION AND PROCEDURE FOR THEIR PREPARATION - Google Patents

PHENYLALKYLAMIN COMPOUNDS EQUIPPED WITH PHARMACOLOGICAL ACTIVITIES IN PARTICULAR ON THE HEART AND ON THE CIRCULATION AND PROCEDURE FOR THEIR PREPARATION

Info

Publication number
IT1172129B
IT1172129B IT49853/81A IT4985381A IT1172129B IT 1172129 B IT1172129 B IT 1172129B IT 49853/81 A IT49853/81 A IT 49853/81A IT 4985381 A IT4985381 A IT 4985381A IT 1172129 B IT1172129 B IT 1172129B
Authority
IT
Italy
Prior art keywords
phenylalkylamin
heart
circulation
procedure
preparation
Prior art date
Application number
IT49853/81A
Other languages
Italian (it)
Other versions
IT8149853A0 (en
Inventor
Johannes Keck
Helmut Pieper
Gerd Kruger
Klaus Noll
Jurgen Dammgen
Willi Diederen
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of IT8149853A0 publication Critical patent/IT8149853A0/en
Application granted granted Critical
Publication of IT1172129B publication Critical patent/IT1172129B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11B—INFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B23/00—Record carriers not specific to the method of recording or reproducing; Accessories, e.g. containers, specially adapted for co-operation with the recording or reproducing apparatus ; Intermediate mediums; Apparatus or processes specially adapted for their manufacture
    • G11B23/02—Containers; Storing means both adapted to cooperate with the recording or reproducing means
    • G11B23/04—Magazines; Cassettes for webs or filaments
    • G11B23/08—Magazines; Cassettes for webs or filaments for housing webs or filaments having two distinct ends
    • G11B23/087—Magazines; Cassettes for webs or filaments for housing webs or filaments having two distinct ends using two different reels or cores
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11B—INFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B25/00—Apparatus characterised by the shape of record carrier employed but not specific to the method of recording or reproducing, e.g. dictating apparatus; Combinations of such apparatus
    • G11B25/06—Apparatus characterised by the shape of record carrier employed but not specific to the method of recording or reproducing, e.g. dictating apparatus; Combinations of such apparatus using web-form record carriers, e.g. tape
    • G11B25/066—Apparatus characterised by the shape of record carrier employed but not specific to the method of recording or reproducing, e.g. dictating apparatus; Combinations of such apparatus using web-form record carriers, e.g. tape adapted for use with containers of different sizes or configurations; adaptor devices therefor

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
IT49853/81A 1980-12-10 1981-12-07 PHENYLALKYLAMIN COMPOUNDS EQUIPPED WITH PHARMACOLOGICAL ACTIVITIES IN PARTICULAR ON THE HEART AND ON THE CIRCULATION AND PROCEDURE FOR THEIR PREPARATION IT1172129B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3046465 1980-12-10

Publications (2)

Publication Number Publication Date
IT8149853A0 IT8149853A0 (en) 1981-12-07
IT1172129B true IT1172129B (en) 1987-06-18

Family

ID=6118763

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49853/81A IT1172129B (en) 1980-12-10 1981-12-07 PHENYLALKYLAMIN COMPOUNDS EQUIPPED WITH PHARMACOLOGICAL ACTIVITIES IN PARTICULAR ON THE HEART AND ON THE CIRCULATION AND PROCEDURE FOR THEIR PREPARATION

Country Status (32)

Country Link
JP (1) JPS57122048A (en)
KR (1) KR870000183B1 (en)
AR (1) AR227802A1 (en)
AT (1) AT379378B (en)
AU (1) AU547655B2 (en)
BE (1) BE891416A (en)
CA (1) CA1202636A (en)
CH (1) CH651541A5 (en)
CS (1) CS229924B2 (en)
DD (1) DD202867A5 (en)
DE (1) DE3146623A1 (en)
DK (1) DK541981A (en)
ES (4) ES507635A0 (en)
FI (1) FI813934L (en)
FR (1) FR2498596B1 (en)
GB (1) GB2088873B (en)
GR (1) GR77323B (en)
HU (1) HU185676B (en)
IE (1) IE52007B1 (en)
IL (1) IL64498A (en)
IT (1) IT1172129B (en)
LU (1) LU83830A1 (en)
NL (1) NL8105170A (en)
NO (1) NO152649C (en)
NZ (1) NZ199215A (en)
PH (1) PH21599A (en)
PL (1) PL129385B1 (en)
PT (1) PT74112B (en)
SE (1) SE8107387L (en)
SU (1) SU1172449A3 (en)
YU (1) YU290381A (en)
ZA (1) ZA818529B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4720586A (en) * 1983-12-06 1988-01-19 Fisons, Plc Substituted 3,4-dihydroxy-phenylethylamino compounds
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
US4943591A (en) * 1984-10-17 1990-07-24 Glaxo Group Limited Dichloroaniline derivatives
GB8426191D0 (en) * 1984-10-17 1984-11-21 Glaxo Holdings Ltd Chemical compounds
GB8603475D0 (en) * 1986-02-12 1986-03-19 Glaxo Group Ltd Chemical compounds
US4959381A (en) * 1987-02-10 1990-09-25 Glaxo Group Limited Pyridine compounds which have useful activity associated with reversible air ways obstruction
GB8703007D0 (en) * 1987-02-10 1987-03-18 Glaxo Group Ltd Chemical compounds
US4906645A (en) * 1988-09-12 1990-03-06 Merck & Co., Inc. Pyridyl aminoethanol compounds with growth promotion and an increase in feed efficiency
DE4028398A1 (en) * 1990-09-07 1992-03-12 Thomae Gmbh Dr K PHENYLETHANOLAMINES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
WO1993007113A1 (en) * 1991-10-04 1993-04-15 Taisho Pharmaceutical Co., Ltd. Alkoxyphenylalkylamine derivative
US8349898B2 (en) * 2008-11-18 2013-01-08 Wisconsin Alumni Research Foundation Sigma-1 receptor ligands and methods of use
GB201208775D0 (en) * 2012-05-18 2012-07-04 Uni I Oslo Chemical compounds
US11999676B2 (en) 2016-04-21 2024-06-04 University Of Kentucky Research Foundation Vesicular monoamine transporter-2 ligands and their use in the treatment of psychostimulant abuse
US10668030B2 (en) * 2016-04-21 2020-06-02 University Of Kentucky Research Foundation Vesicular monoamine transporter-2 ligands and their use in the treatment of psychostimulant abuse
WO2023235153A1 (en) * 2022-05-31 2023-12-07 Corteva Agriscience Llc Crystalline forms of picolinamide fungicide compound

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1618007A1 (en) * 1967-05-09 1970-10-29 Thomae Gmbh Dr K Process for the production of new amino-monohalophenylaethanolamines
DE2351281C3 (en) * 1973-10-12 1981-07-30 Dr. Karl Thomae Gmbh, 7950 Biberach Aminophenylethanolamine derivatives, their production and use
NL176168C (en) * 1972-12-18 1985-03-01 Thomae Gmbh Dr K PROCEDURE FOR THE PREPARATION OR MANUFACTURE OF A PHARMACEUTICAL PREPARATION AND METHOD FOR THE PREPARATION OF USEFUL NEW SUBSTITUTED 1-(4-AMINOPHENYL)-2-AMINO-ETHANOL DERIVATIVES WHICH, EXCEPT AN ANALGETIC, UTERUS SPASMOLYTIC AND ANTI-SPASTIC ACTIVITY, HAVE RELATIVE STRIPES IN PARTICULAR HAVE A BETA2 MIMETIC AND/OR BETA1 BLOCKING ACTIVITY.
GB1523974A (en) * 1975-02-05 1978-09-06 Yamanouchi Pharma Co Ltd 4-substituted amino- -aminomethylbenzyl alcohol derivatives
JPS51125232A (en) * 1975-02-05 1976-11-01 Yamanouchi Pharmaceut Co Ltd Process for preparing 4-substituted amido-3,5-dihalogeno-alpha-substituted aminomethylbenzyl alcohols
EP0006961A1 (en) * 1978-02-21 1980-01-23 Sandoz Ag New phenylethylamines, process for their preparation, and pharmaceutical compositions containing them
IL57670A (en) * 1978-07-03 1982-11-30 Lilly Co Eli Phenethanolamines,their preparation and pharmaceutical formulations comprising them

Also Published As

Publication number Publication date
FR2498596B1 (en) 1986-03-21
PT74112A (en) 1982-01-01
CS229924B2 (en) 1984-07-16
CA1202636A (en) 1986-04-01
YU290381A (en) 1983-10-31
ZA818529B (en) 1983-08-31
PT74112B (en) 1984-10-09
IL64498A0 (en) 1982-03-31
HU185676B (en) 1985-03-28
ES512914A0 (en) 1983-03-01
AR227802A1 (en) 1982-12-15
AU547655B2 (en) 1985-10-31
ES8304538A1 (en) 1983-03-01
IE52007B1 (en) 1987-05-13
AU7841481A (en) 1982-09-23
NO152649B (en) 1985-07-22
NO152649C (en) 1985-10-30
ES512913A0 (en) 1983-03-01
DE3146623A1 (en) 1982-07-15
BE891416A (en) 1982-06-09
PL129385B1 (en) 1984-05-31
IT8149853A0 (en) 1981-12-07
IL64498A (en) 1985-08-30
KR870000183B1 (en) 1987-02-14
ES8301890A1 (en) 1983-01-01
FI813934L (en) 1982-06-11
AT379378B (en) 1985-12-27
NO814194L (en) 1982-06-11
DK541981A (en) 1982-06-11
LU83830A1 (en) 1983-04-13
ES8304536A1 (en) 1983-03-01
ES507635A0 (en) 1983-01-01
SU1172449A3 (en) 1985-08-07
KR830007505A (en) 1983-10-21
NL8105170A (en) 1982-07-01
IE812888L (en) 1982-06-10
DD202867A5 (en) 1983-10-05
NZ199215A (en) 1986-07-11
PL234155A1 (en) 1982-08-02
ES8304537A1 (en) 1983-03-01
GB2088873B (en) 1984-10-17
GR77323B (en) 1984-09-11
PH21599A (en) 1987-12-11
SE8107387L (en) 1982-07-26
ES512915A0 (en) 1983-03-01
GB2088873A (en) 1982-06-16
ATA512981A (en) 1985-05-15
CH651541A5 (en) 1985-09-30
FR2498596A1 (en) 1982-07-30
JPS57122048A (en) 1982-07-29

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