IT1169774B - Composizioni terapeutiche iniettabili contenenti sali stabili della s-adenosil-l-metionina - Google Patents

Composizioni terapeutiche iniettabili contenenti sali stabili della s-adenosil-l-metionina

Info

Publication number
IT1169774B
IT1169774B IT22623/83A IT2262383A IT1169774B IT 1169774 B IT1169774 B IT 1169774B IT 22623/83 A IT22623/83 A IT 22623/83A IT 2262383 A IT2262383 A IT 2262383A IT 1169774 B IT1169774 B IT 1169774B
Authority
IT
Italy
Prior art keywords
therapeutic compositions
adenosyl
methionine
compositions containing
stable salts
Prior art date
Application number
IT22623/83A
Other languages
English (en)
Italian (it)
Other versions
IT8322623A0 (it
IT8322623A1 (it
Inventor
Federico Gennari
Original Assignee
Bioresearch Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresearch Spa filed Critical Bioresearch Spa
Publication of IT8322623A0 publication Critical patent/IT8322623A0/it
Priority to IT22623/83A priority Critical patent/IT1169774B/it
Priority to JP58244953A priority patent/JPS6048925A/ja
Priority to EP84109108A priority patent/EP0136463B1/en
Priority to AT84109108T priority patent/ATE47518T1/de
Priority to DE8484109108T priority patent/DE3480258D1/de
Priority to CA000460361A priority patent/CA1225032A/en
Priority to AU32327/84A priority patent/AU564269B2/en
Publication of IT8322623A1 publication Critical patent/IT8322623A1/it
Priority to US06/784,855 priority patent/US5114931A/en
Application granted granted Critical
Publication of IT1169774B publication Critical patent/IT1169774B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT22623/83A 1983-08-24 1983-08-24 Composizioni terapeutiche iniettabili contenenti sali stabili della s-adenosil-l-metionina IT1169774B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT22623/83A IT1169774B (it) 1983-08-24 1983-08-24 Composizioni terapeutiche iniettabili contenenti sali stabili della s-adenosil-l-metionina
JP58244953A JPS6048925A (ja) 1983-08-24 1983-12-27 安定なｓ−アデノシル−ｌ−メチオニン塩を含有する注射可能な治療用組成物
DE8484109108T DE3480258D1 (en) 1983-08-24 1984-08-01 Injectable therapeutic compositions containing stable s-adenosyl-l-methionine salts
AT84109108T ATE47518T1 (de) 1983-08-24 1984-08-01 Injizierbare pharmazeutische zusammenstellungen die bestaendige 5-adenosyl-l-methionin-salze enthalten.
EP84109108A EP0136463B1 (en) 1983-08-24 1984-08-01 Injectable therapeutic compositions containing stable s-adenosyl-l-methionine salts
CA000460361A CA1225032A (en) 1983-08-24 1984-08-03 Injectable therapeutic compositions containing stable s-adenosyl-l-methionine salts
AU32327/84A AU564269B2 (en) 1983-08-24 1984-08-23 Compositions containing s-adenosyl-l methionine
US06/784,855 US5114931A (en) 1983-08-24 1985-10-04 Injectable therapeutic compositions containing stable s-adenosyl-l-methionine salts

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22623/83A IT1169774B (it) 1983-08-24 1983-08-24 Composizioni terapeutiche iniettabili contenenti sali stabili della s-adenosil-l-metionina

Publications (3)

Publication Number Publication Date
IT8322623A0 IT8322623A0 (it) 1983-08-24
IT8322623A1 IT8322623A1 (it) 1985-02-24
IT1169774B true IT1169774B (it) 1987-06-03

Family

ID=11198546

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22623/83A IT1169774B (it) 1983-08-24 1983-08-24 Composizioni terapeutiche iniettabili contenenti sali stabili della s-adenosil-l-metionina

Country Status (8)

Country Link
US (1) US5114931A (OSRAM)
EP (1) EP0136463B1 (OSRAM)
JP (1) JPS6048925A (OSRAM)
AT (1) ATE47518T1 (OSRAM)
AU (1) AU564269B2 (OSRAM)
CA (1) CA1225032A (OSRAM)
DE (1) DE3480258D1 (OSRAM)
IT (1) IT1169774B (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1229479B (it) * 1989-03-13 1991-09-03 Bioresearch Spa Impiego di 5' deossi 5' metiltioadenosina, di s adenosilmetionina e dei loro sali per la preparazione di composizioni farmaceutiche atte a favorire la crescita dei capelli in soggetti affetti da calvizie e composizioni farmaceutiche relative.
IT1247903B (it) * 1991-02-25 1995-01-05 Bioresearch Spa Impiego della s-adenosil-l-metionina nel trattamento della colestasi intraepatica da nutrizione parenterale totale
JPH06192109A (ja) * 1992-09-04 1994-07-12 Fuji Kagaku Kogyo Kk 抗腫瘍効果増強剤
IT1317920B1 (it) * 2000-10-20 2003-07-15 Univ Roma S-adenosilmetionina e suoi derivati per il trattamento e laprevenzione della malattia di alzheimer.
US6759395B2 (en) 2000-12-18 2004-07-06 Orchid Chemicals & Pharmaceuticals, Ltd. Soft-gelatin capsule comprising S-adenosylmethionine and a method for producing the same
US20050272687A1 (en) * 2004-06-08 2005-12-08 Hebert Rolland F Stable S-adenosyl-l-methionine
US20090012036A1 (en) * 2005-05-24 2009-01-08 Hebert Rolland F Stable S-adenosyl-L-methionine
EP2945959B1 (en) 2013-01-16 2020-05-13 Hebert Sam-E LLC Stable indole-3-propionate salts of s-adenosyl-l-methionine
IT201900015192A1 (it) * 2019-08-29 2021-03-01 Graal S R L Formulazioni edibili a base di principi attivi e arginina

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE37913B1 (en) * 1972-08-02 1977-11-09 Bioresearch Sas Salt of s-adenosyl-l-methionine
AR221676A1 (es) * 1974-07-12 1981-03-13 Bioresearch Sas Procedimiento para la preparacion de sales estables sulfonicas y/o sulfuricas de la s-adenosil-l-metionina,particularmente utiles como donadores especificos de metilo para las reacciones bioquimicas de transferencia del grupo ch3;asi como tambien las reacciones fundamentales en el metabolismo lipilico,protilico y glucidico
JPS5195120A (en) * 1975-02-10 1976-08-20 Tenganekino seizoho
IT1137892B (it) * 1981-08-24 1986-09-10 Bioresearch Srl Sali stabili della s-adenosilmetionina,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo
JPS5841898A (ja) * 1981-09-07 1983-03-11 Yamasa Shoyu Co Ltd Ｓ−アデノシル−ｌ−ホモシステインの製造法

Also Published As

Publication number Publication date
EP0136463A2 (en) 1985-04-10
US5114931A (en) 1992-05-19
AU564269B2 (en) 1987-08-06
DE3480258D1 (en) 1989-11-30
EP0136463A3 (en) 1985-06-12
CA1225032A (en) 1987-08-04
JPS6048925A (ja) 1985-03-16
IT8322623A0 (it) 1983-08-24
ATE47518T1 (de) 1989-11-15
AU3232784A (en) 1985-02-28
IT8322623A1 (it) 1985-02-24
JPH027575B2 (OSRAM) 1990-02-19
EP0136463B1 (en) 1989-10-25

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Effective date: 19960830