IT1167113B - Composizione farmaceutica contenente un composto di 1,4-benzochinone e suo impiego come agente antifibrotico - Google Patents

Composizione farmaceutica contenente un composto di 1,4-benzochinone e suo impiego come agente antifibrotico

Info

Publication number
IT1167113B
IT1167113B IT48031/83A IT4803183A IT1167113B IT 1167113 B IT1167113 B IT 1167113B IT 48031/83 A IT48031/83 A IT 48031/83A IT 4803183 A IT4803183 A IT 4803183A IT 1167113 B IT1167113 B IT 1167113B
Authority
IT
Italy
Prior art keywords
benzokinone
compound
pharmaceutical composition
composition containing
antifibrotic agent
Prior art date
Application number
IT48031/83A
Other languages
English (en)
Other versions
IT8348031A0 (it
Inventor
Isuke Imada
Masazumi Watanabe
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of IT8348031A0 publication Critical patent/IT8348031A0/it
Application granted granted Critical
Publication of IT1167113B publication Critical patent/IT1167113B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT48031/83A 1982-04-06 1983-03-31 Composizione farmaceutica contenente un composto di 1,4-benzochinone e suo impiego come agente antifibrotico IT1167113B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57057474A JPS58174313A (ja) 1982-04-06 1982-04-06 動物組織の線維化抑制剤

Publications (2)

Publication Number Publication Date
IT8348031A0 IT8348031A0 (it) 1983-03-31
IT1167113B true IT1167113B (it) 1987-05-13

Family

ID=13056694

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48031/83A IT1167113B (it) 1982-04-06 1983-03-31 Composizione farmaceutica contenente un composto di 1,4-benzochinone e suo impiego come agente antifibrotico

Country Status (4)

Country Link
US (1) US4514420A (it)
JP (1) JPS58174313A (it)
DE (1) DE3311922C2 (it)
IT (1) IT1167113B (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3680023D1 (de) * 1985-04-08 1991-08-08 Takeda Chemical Industries Ltd Benzochinonderivate, ihre herstellung und verwendung.
WO1987001698A2 (en) * 1985-09-20 1987-03-26 The Upjohn Company 1,4-naphthalenediol and 1,4-hydroquinone derivatives
US4939169A (en) * 1985-09-20 1990-07-03 The Upjohn Company 1,4-naphthalenediol and 1,4-hydroquinone derivatives
ATE74269T1 (de) * 1987-07-29 1992-04-15 Takeda Chemical Industries Ltd Zellproliferationsinhibitor.
US5789426A (en) * 1995-01-20 1998-08-04 Cornell Research Foundation, Inc. Method for the treatment of fibroproliferative disorders by application of inhibitors of protein hydroxylation
EP0788793A1 (en) 1996-02-01 1997-08-13 Takeda Chemical Industries, Ltd. Idebenone for the treatment of dementia
EP0813866A3 (en) * 1996-06-17 1999-01-20 Eisai Co., Ltd. Therapeutic agent for joint diseases
EP2563908B1 (en) 2010-04-25 2019-01-09 Icahn School of Medicine at Mount Sinai Generation of anterior foregut endoderm from pluripotent cells
WO2014018691A1 (en) * 2012-07-24 2014-01-30 The Trustees Of Columbia University In The City Of New York Generation of airway and lung progenitors and epithelial cells and three-dimensional anterior foregut spheres
JP7169580B2 (ja) * 2018-09-27 2022-11-11 株式会社Ｌｔｔバイオファーマ 線維症治療用医薬組成物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4271083A (en) * 1974-05-02 1981-06-02 Takeda Chemical Industries, Ltd. 6-Hydroxy-1,4-benzoquinone compounds
JPS5919930B2 (ja) * 1974-05-02 1984-05-09 武田薬品工業株式会社 キノン酸誘導体の製造法
JPS54160740A (en) * 1978-06-09 1979-12-19 Takeda Chem Ind Ltd Anti-fibrotic agent
DE3069496D1 (de) * 1979-06-28 1984-11-29 Takeda Chemical Industries Ltd 2,3-dialkoxy-1,4-quinone derivatives; method of producing 1,4-quinone derivatives
JPS5697223A (en) * 1979-12-30 1981-08-05 Takeda Chem Ind Ltd Tissue metabolism activator
JPS56150014A (en) * 1980-04-21 1981-11-20 Takeda Chem Ind Ltd Antiallergic agent

Also Published As

Publication number Publication date
DE3311922C2 (de) 1994-06-23
US4514420A (en) 1985-04-30
DE3311922A1 (de) 1983-10-13
JPH0139405B2 (it) 1989-08-21
IT8348031A0 (it) 1983-03-31
JPS58174313A (ja) 1983-10-13

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950322