IT1164062B - Composizione farmaceutica comprendente una acil-carnitina per il trattamento del rallentato metabolismo cerebrale - Google Patents
Composizione farmaceutica comprendente una acil-carnitina per il trattamento del rallentato metabolismo cerebraleInfo
- Publication number
- IT1164062B IT1164062B IT50795/79A IT5079579A IT1164062B IT 1164062 B IT1164062 B IT 1164062B IT 50795/79 A IT50795/79 A IT 50795/79A IT 5079579 A IT5079579 A IT 5079579A IT 1164062 B IT1164062 B IT 1164062B
- Authority
- IT
- Italy
- Prior art keywords
- cerebral
- vascular disorders
- induced
- compsns
- carnitine
- Prior art date
Links
- 230000002490 cerebral effect Effects 0.000 title abstract 6
- 208000019553 vascular disease Diseases 0.000 title abstract 2
- MEFKEPWMEQBLKI-AIRLBKTGSA-O S-adenosyl-L-methionine Chemical compound O[C@@H]1[C@H](O)[C@@H](C[S+](CC[C@H]([NH3+])C([O-])=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 MEFKEPWMEQBLKI-AIRLBKTGSA-O 0.000 title 1
- 241000282326 Felis catus Species 0.000 abstract 1
- RDHQFKQIGNGIED-MRVPVSSYSA-N O-acetyl-L-carnitine Chemical compound CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C RDHQFKQIGNGIED-MRVPVSSYSA-N 0.000 abstract 1
- 125000002339 acetoacetyl group Chemical group O=C([*])C([H])([H])C(=O)C([H])([H])[H] 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 229960001009 acetylcarnitine Drugs 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000004075 alteration Effects 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 230000008499 blood brain barrier function Effects 0.000 abstract 1
- 210000001218 blood-brain barrier Anatomy 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 125000004063 butyryl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 230000010339 dilation Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- -1 hydroxybutyryl Chemical group 0.000 abstract 1
- 238000010253 intravenous injection Methods 0.000 abstract 1
- 210000003140 lateral ventricle Anatomy 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 230000037023 motor activity Effects 0.000 abstract 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 210000001747 pupil Anatomy 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000035939 shock Effects 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT50795/79A IT1164062B (it) | 1979-11-09 | 1979-11-09 | Composizione farmaceutica comprendente una acil-carnitina per il trattamento del rallentato metabolismo cerebrale |
| US06/119,075 US4346107A (en) | 1979-02-12 | 1980-02-05 | Pharmaceutical composition comprising acyl-carnitine for the treatment of impaired cerebral metabolism |
| AU55267/80A AU535518B2 (en) | 1979-02-12 | 1980-02-06 | Pharmaceutical compositions of acyl-carnitine |
| NL8000768A NL8000768A (nl) | 1979-02-12 | 1980-02-07 | Een acyl-carnitine bevattend farmaceutisch preparaat. |
| CH102880A CH641673A5 (it) | 1979-02-12 | 1980-02-08 | Composizione farmaceutica comprendente una acil-carnitina per il trattamento del rallentato metabolismo cerebrale. |
| BE0/199368A BE881680A (fr) | 1979-02-12 | 1980-02-12 | Composition pharmaceutique a base d'acylcarnitine pour le traitement d'un metabolisme cerebral altere et methode utilisee a cet effet |
| DE19803005208 DE3005208A1 (de) | 1979-02-12 | 1980-02-12 | Verwendung von acylcarnitin in arzneimitteln zur behandlung von stoerungen im gehirn-metabolismus |
| GB8004602A GB2046593A (en) | 1979-02-12 | 1980-02-12 | Pharmaceutical compositions comprising acyl-carnitine for the treatment of impaired cerebral metabolism |
| FR8003015A FR2448348A1 (fr) | 1979-02-12 | 1980-02-12 | Composition pharmaceutique comprenant une acyl-carnitine pour le traitement du metabolisme cerebral perturbe |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT50795/79A IT1164062B (it) | 1979-11-09 | 1979-11-09 | Composizione farmaceutica comprendente una acil-carnitina per il trattamento del rallentato metabolismo cerebrale |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7950795A0 IT7950795A0 (it) | 1979-11-09 |
| IT1164062B true IT1164062B (it) | 1987-04-08 |
Family
ID=11273730
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT50795/79A IT1164062B (it) | 1979-02-12 | 1979-11-09 | Composizione farmaceutica comprendente una acil-carnitina per il trattamento del rallentato metabolismo cerebrale |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1164062B (it) |
-
1979
- 1979-11-09 IT IT50795/79A patent/IT1164062B/it active Protection Beyond IP Right Term
Also Published As
| Publication number | Publication date |
|---|---|
| IT7950795A0 (it) | 1979-11-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ITCP | Complementary protection certificate |
Free format text: CCP 4 |
|
| MEDD | Supplementary protection certificate for pharmaceutical products: granted |
Free format text: CCP 4, 19911219; SIGMA-TAU INDUSTRIE FARMACEUTICHE R IUNITE S.P.A. |
|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19961004 |