IT1126443B - Alcool beta,gamma-diidropoliprenilico e composizione farmaceutica ipotensiva che lo contiene - Google Patents

Alcool beta,gamma-diidropoliprenilico e composizione farmaceutica ipotensiva che lo contiene

Info

Publication number
IT1126443B
IT1126443B IT27750/79A IT2775079A IT1126443B IT 1126443 B IT1126443 B IT 1126443B IT 27750/79 A IT27750/79 A IT 27750/79A IT 2775079 A IT2775079 A IT 2775079A IT 1126443 B IT1126443 B IT 1126443B
Authority
IT
Italy
Prior art keywords
hypothensive
dihydropoliprenyl
range
pharmaceutical composition
alcohol beta
Prior art date
Application number
IT27750/79A
Other languages
English (en)
Other versions
IT7927750A0 (it
Inventor
Isao Yamatsu
Shinya Abe
Yuichi Inai
Toshiji Igarashi
Yoshikage Nakajima
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of IT7927750A0 publication Critical patent/IT7927750A0/it
Application granted granted Critical
Publication of IT1126443B publication Critical patent/IT1126443B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/02Acyclic alcohols with carbon-to-carbon double bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/08Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03Monocarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT27750/79A 1978-12-01 1979-11-30 Alcool beta,gamma-diidropoliprenilico e composizione farmaceutica ipotensiva che lo contiene IT1126443B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP53147858A JPS6058209B2 (ja) 1978-12-01 1978-12-01 β,γ−ジヒドロポリプレニルアルコ−ルおよびそれからなる血圧降下剤

Publications (2)

Publication Number Publication Date
IT7927750A0 IT7927750A0 (it) 1979-11-30
IT1126443B true IT1126443B (it) 1986-05-21

Family

ID=15439838

Family Applications (1)

Application Number Title Priority Date Filing Date
IT27750/79A IT1126443B (it) 1978-12-01 1979-11-30 Alcool beta,gamma-diidropoliprenilico e composizione farmaceutica ipotensiva che lo contiene

Country Status (11)

Country Link
US (1) US4325974A (it)
JP (1) JPS6058209B2 (it)
CA (1) CA1120500A (it)
CH (1) CH641347A5 (it)
DE (1) DE2947624A1 (it)
ES (1) ES486515A0 (it)
FR (1) FR2442819B1 (it)
GB (1) GB2038818B (it)
IT (1) IT1126443B (it)
NL (1) NL7908705A (it)
SE (1) SE444931B (it)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0041235B1 (en) * 1980-05-30 1985-02-13 Eisai Co., Ltd. Alpha,beta-dihydropolyprenyl derivatives for treating liver diseases
JPS5791932A (en) * 1980-11-28 1982-06-08 Kuraray Co Ltd Polyprenyl compound
JPS58167555A (ja) * 1982-03-29 1983-10-03 Kuraray Co Ltd ポリプレニル化合物
US5658958A (en) * 1982-05-28 1997-08-19 Eisai Co., Ltd. β, γ-dihydropolyprenyl alcohol derivatives effective at mitigating stress in animals
GB2159709B (en) * 1982-05-28 1987-04-08 Eisai Co Ltd Containing a polyprenyl compound
US5280048A (en) * 1982-05-28 1994-01-18 Eisai Co., Ltd. β,γ-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound
DE3348500C2 (de) * 1982-05-28 1998-10-22 Eisai Co Ltd beta,gamma-Dihydropolyprenylalkoholderivat
JPS59152354A (ja) * 1983-02-21 1984-08-31 Nisshin Flour Milling Co Ltd イソプレニル酸アミド誘導体
EP0149847A3 (en) * 1983-12-26 1989-11-08 Eisai Co., Ltd. Therapeutic and preventive agent containing dolichol
JPS60136511A (ja) * 1983-12-26 1985-07-20 Eisai Co Ltd 高尿酸血症治療剤
JPS60136510A (ja) * 1983-12-26 1985-07-20 Eisai Co Ltd 肝疾患治療・予防剤
JPS60136512A (ja) * 1983-12-26 1985-07-20 Eisai Co Ltd 脂質代謝改善剤
JPS60136513A (ja) * 1983-12-26 1985-07-20 Eisai Co Ltd 糖尿病治療剤
CA2269680A1 (en) * 1996-12-12 1998-06-18 Pharmacia & Upjohn Company An oil composition of dihydropolyprenols

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL252912A (it) * 1959-06-23
US3449407A (en) * 1966-01-11 1969-06-10 Int Flavors & Fragrances Inc Lactic acid esters of polyisoprenoid alcohols
FR2041421A5 (en) * 1969-04-23 1971-01-29 Inst Francais Du Petrole Tetramethyl dinitriles prepn
GB1420886A (en) * 1973-01-31 1976-01-14 Teikoku Chem Ind Co Ltd Preparation of polyene compounds and intermediates for the use therein
US3845108A (en) * 1973-08-31 1974-10-29 W Roelofs Trans-7-cis-9-dodecadien-1-yl acetate
US3953532A (en) * 1974-04-25 1976-04-27 Zoecon Corporation 4,8-Tridecadien-1-ol,4 cis,8 cis,trans
US3971827A (en) * 1974-09-09 1976-07-27 G. D. Searle & Co. Manufacture of poly-(cis)-isoprenols
JPS5826327B2 (ja) 1974-11-22 1983-06-02 エ−ザイ カブシキガイシヤ ホコウソキユウルイノ ゴウセイホウ
US3985814A (en) * 1975-02-28 1976-10-12 Celanese Corporation Production of alcohols from carboxylic acids
US4198532A (en) * 1977-08-04 1980-04-15 Givaudan Corporation Novel alcohol odorants

Also Published As

Publication number Publication date
ES8101530A1 (es) 1980-12-16
CH641347A5 (fr) 1984-02-29
FR2442819B1 (fr) 1985-12-27
JPS6058209B2 (ja) 1985-12-19
ES486515A0 (es) 1980-12-16
GB2038818B (en) 1983-02-16
IT7927750A0 (it) 1979-11-30
SE444931B (sv) 1986-05-20
FR2442819A1 (fr) 1980-06-27
CA1120500A (en) 1982-03-23
GB2038818A (en) 1980-07-30
NL7908705A (nl) 1980-06-03
US4325974A (en) 1982-04-20
JPS5576829A (en) 1980-06-10
DE2947624A1 (de) 1980-06-12
SE7909916L (sv) 1980-06-02

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