IT1105670B - Amidino-urea derivs. prodn. - by reacting carbamoyl deriv. with guanidine cpd - Google Patents
Amidino-urea derivs. prodn. - by reacting carbamoyl deriv. with guanidine cpdInfo
- Publication number
- IT1105670B IT1105670B IT8341578A IT8341578A IT1105670B IT 1105670 B IT1105670 B IT 1105670B IT 8341578 A IT8341578 A IT 8341578A IT 8341578 A IT8341578 A IT 8341578A IT 1105670 B IT1105670 B IT 1105670B
- Authority
- IT
- Italy
- Prior art keywords
- alkyl
- deriv
- prodn
- amidino
- cpd
- Prior art date
Links
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 title 2
- SQSPRWMERUQXNE-UHFFFAOYSA-N Guanylurea Chemical compound NC(=N)NC(N)=O SQSPRWMERUQXNE-UHFFFAOYSA-N 0.000 title 1
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 title 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 title 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 8
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- AKLIBMCMOOPIEM-UHFFFAOYSA-N 1-(diaminomethylidene)-3-phenylurea Chemical compound NC(N)=NC(=O)NC1=CC=CC=C1 AKLIBMCMOOPIEM-UHFFFAOYSA-N 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Prepn. of 1-phenyl-3-amidinourea derivs. of formula (I) is as follows: (X, Y and Z are H, halogen, NO2, OH, acyloxy, CN, 1-5C alkyl, haloalkyl, alkoxy, haloalkoxy or alkylsulphonyl or aryl-(1-5C)alkoxy; R and R1 are H or 1-5C alkyl; R2 and R3 are H, 1-10C alkyl, lower alkenyl, 3-7C cyclo-alkyl, 3-9C cycloalkenyl, aryl-(1-10C)alkyl, (3-7C)cyclo-alkyl-(1-5C)alkyl or lower alkynyl; or R2 + R3 may form a 5- to 7-membered ring opt. including 1 or 2 N, O or S; R4 is H or 1-5C alkyl; and R8 is 1-5C alkyl, Ph or Ph-(1-5C)alkyl; provided that >=1 of R-R3 is other than H).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8341578A IT1105670B (en) | 1978-07-04 | 1978-07-04 | Amidino-urea derivs. prodn. - by reacting carbamoyl deriv. with guanidine cpd |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8341578A IT1105670B (en) | 1978-07-04 | 1978-07-04 | Amidino-urea derivs. prodn. - by reacting carbamoyl deriv. with guanidine cpd |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7883415A0 IT7883415A0 (en) | 1978-07-04 |
| IT1105670B true IT1105670B (en) | 1985-11-04 |
Family
ID=11321546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8341578A IT1105670B (en) | 1978-07-04 | 1978-07-04 | Amidino-urea derivs. prodn. - by reacting carbamoyl deriv. with guanidine cpd |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1105670B (en) |
-
1978
- 1978-07-04 IT IT8341578A patent/IT1105670B/en active
Also Published As
| Publication number | Publication date |
|---|---|
| IT7883415A0 (en) | 1978-07-04 |
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