NL7803152A - Amidino-urea derivs. prodn. - by reacting carbamoyl deriv. with guanidine cpd - Google Patents

Amidino-urea derivs. prodn. - by reacting carbamoyl deriv. with guanidine cpd

Info

Publication number
NL7803152A
NL7803152A NL7803152A NL7803152A NL7803152A NL 7803152 A NL7803152 A NL 7803152A NL 7803152 A NL7803152 A NL 7803152A NL 7803152 A NL7803152 A NL 7803152A NL 7803152 A NL7803152 A NL 7803152A
Authority
NL
Netherlands
Prior art keywords
alkyl
deriv
prodn
amidino
cpd
Prior art date
Application number
NL7803152A
Other languages
Dutch (nl)
Original Assignee
Rorer Inc William H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rorer Inc William H filed Critical Rorer Inc William H
Priority to NL7803152A priority Critical patent/NL7803152A/en
Publication of NL7803152A publication Critical patent/NL7803152A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215Radicals derived from nitrogen analogues of carbonic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24Y being a hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Prepn. of 1-phenyl-3-amidinourea derivs. of formula (I) is as follows: (X, Y and Z are H, halogen, NO2, OH, acyloxy, CN, 1-5C alkyl, haloalkyl, alkoxy, haloalkoxy or alkylsulphonyl or aryl-(1-5C)alkoxy; R and R1 are H or 1-5C alkyl; R2 and R3 are H, 1-10C alkyl, lower alkenyl, 3-7C cyclo-alkyl, 3-9C cycloalkenyl, aryl-(1-10C)alkyl, (3-7C)cyclo-alkyl-(1-5C)alkyl or lower alkynyl; or R2 + R3 may form a 5- to 7-membered ring opt. including 1 or 2 N, O or S; R4 is H or 1-5C alkyl; and R8 is 1-5C alkyl, Ph or Ph-(1-5C)alkyl; provided that >=1 of R-R3 is other than H).
NL7803152A 1978-03-23 1978-03-23 Amidino-urea derivs. prodn. - by reacting carbamoyl deriv. with guanidine cpd NL7803152A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NL7803152A NL7803152A (en) 1978-03-23 1978-03-23 Amidino-urea derivs. prodn. - by reacting carbamoyl deriv. with guanidine cpd

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7803152A NL7803152A (en) 1978-03-23 1978-03-23 Amidino-urea derivs. prodn. - by reacting carbamoyl deriv. with guanidine cpd

Publications (1)

Publication Number Publication Date
NL7803152A true NL7803152A (en) 1979-09-25

Family

ID=19830546

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7803152A NL7803152A (en) 1978-03-23 1978-03-23 Amidino-urea derivs. prodn. - by reacting carbamoyl deriv. with guanidine cpd

Country Status (1)

Country Link
NL (1) NL7803152A (en)

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BV The patent application has lapsed