IT1096161B - Indolo-diidroindolo dimerico,utile quale agente anti-tumorale - Google Patents

Indolo-diidroindolo dimerico,utile quale agente anti-tumorale

Info

Publication number
IT1096161B
IT1096161B IT21726/78A IT2172678A IT1096161B IT 1096161 B IT1096161 B IT 1096161B IT 21726/78 A IT21726/78 A IT 21726/78A IT 2172678 A IT2172678 A IT 2172678A IT 1096161 B IT1096161 B IT 1096161B
Authority
IT
Italy
Prior art keywords
indolo
dihydroindole
dimeric
useful
tumoral agent
Prior art date
Application number
IT21726/78A
Other languages
English (en)
Other versions
IT7821726A0 (it
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IT7821726A0 publication Critical patent/IT7821726A0/it
Application granted granted Critical
Publication of IT1096161B publication Critical patent/IT1096161B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT21726/78A 1977-03-30 1978-03-29 Indolo-diidroindolo dimerico,utile quale agente anti-tumorale IT1096161B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/782,644 US4115388A (en) 1977-03-30 1977-03-30 3'-Oxygenated derivatives of 4'-deoxy VLB "A" and "B" and related 1-formyl compounds

Publications (2)

Publication Number Publication Date
IT7821726A0 IT7821726A0 (it) 1978-03-29
IT1096161B true IT1096161B (it) 1985-08-17

Family

ID=25126725

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21726/78A IT1096161B (it) 1977-03-30 1978-03-29 Indolo-diidroindolo dimerico,utile quale agente anti-tumorale

Country Status (14)

Country Link
US (1) US4115388A (it)
JP (1) JPS53130699A (it)
AR (1) AR224342A1 (it)
BE (1) BE865406A (it)
CA (1) CA1097628A (it)
CH (1) CH634849A5 (it)
DE (1) DE2813286A1 (it)
FR (1) FR2385724A1 (it)
GB (1) GB1596235A (it)
HU (1) HU182482B (it)
IE (1) IE46692B1 (it)
IL (1) IL54357A (it)
IT (1) IT1096161B (it)
NL (1) NL7803253A (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4203898A (en) * 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids
US4166810A (en) * 1978-04-20 1979-09-04 Eli Lilly And Company Derivatives of 4-desacetyl VLB C-3 carboxyhydrazide
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
HU185691B (en) * 1982-02-09 1985-03-28 Richter Gedeon Vegyeszet Process for preparing a new analgetic pharmaceutical composition
US4841045A (en) * 1985-03-12 1989-06-20 University Of Vermont & State Agricultural College Synthesis of vinblastine and vincristine type compounds
US4897477A (en) * 1985-03-12 1990-01-30 University Of Vermont & State Agricultural College Synthesis of vinblastine and vincristine type compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3352868A (en) * 1964-04-01 1967-11-14 Lilly Co Eli Dihydrovinblastine
US3887565A (en) * 1974-05-06 1975-06-03 Lilly Co Eli Vincadioline
FR2296418B1 (it) * 1974-12-30 1978-07-21 Anvar
US3944554A (en) * 1975-01-09 1976-03-16 Eli Lilly And Company 4-Desacetoxy-3-hydroxyvinblastine

Also Published As

Publication number Publication date
GB1596235A (en) 1981-08-19
DE2813286A1 (de) 1978-10-05
US4115388A (en) 1978-09-19
IE46692B1 (en) 1983-08-24
HU182482B (en) 1984-01-30
IT7821726A0 (it) 1978-03-29
CA1097628A (en) 1981-03-17
CH634849A5 (de) 1983-02-28
FR2385724B1 (it) 1981-03-06
NL7803253A (nl) 1978-10-03
IL54357A (en) 1982-11-30
AR224342A1 (es) 1981-11-30
FR2385724A1 (fr) 1978-10-27
BE865406A (fr) 1978-09-29
JPS53130699A (en) 1978-11-14
IE780610L (en) 1978-09-30
IL54357A0 (en) 1978-06-15

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