IL54357A - Derivatives of 3'-oxo(or hydroxy)4'-deoxy vlb"a"and"b"and related 1-formyl compounds,their preparation and antitumor pharmaceutical compositions containing them - Google Patents
Derivatives of 3'-oxo(or hydroxy)4'-deoxy vlb"a"and"b"and related 1-formyl compounds,their preparation and antitumor pharmaceutical compositions containing themInfo
- Publication number
- IL54357A IL54357A IL54357A IL5435778A IL54357A IL 54357 A IL54357 A IL 54357A IL 54357 A IL54357 A IL 54357A IL 5435778 A IL5435778 A IL 5435778A IL 54357 A IL54357 A IL 54357A
- Authority
- IL
- Israel
- Prior art keywords
- oxo
- hydroxy
- derivatives
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/782,644 US4115388A (en) | 1977-03-30 | 1977-03-30 | 3'-Oxygenated derivatives of 4'-deoxy VLB "A" and "B" and related 1-formyl compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL54357A0 IL54357A0 (en) | 1978-06-15 |
| IL54357A true IL54357A (en) | 1982-11-30 |
Family
ID=25126725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL54357A IL54357A (en) | 1977-03-30 | 1978-03-27 | Derivatives of 3'-oxo(or hydroxy)4'-deoxy vlb"a"and"b"and related 1-formyl compounds,their preparation and antitumor pharmaceutical compositions containing them |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4115388A (xx) |
| JP (1) | JPS53130699A (xx) |
| AR (1) | AR224342A1 (xx) |
| BE (1) | BE865406A (xx) |
| CA (1) | CA1097628A (xx) |
| CH (1) | CH634849A5 (xx) |
| DE (1) | DE2813286A1 (xx) |
| FR (1) | FR2385724A1 (xx) |
| GB (1) | GB1596235A (xx) |
| HU (1) | HU182482B (xx) |
| IE (1) | IE46692B1 (xx) |
| IL (1) | IL54357A (xx) |
| IT (1) | IT1096161B (xx) |
| NL (1) | NL7803253A (xx) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4203898A (en) * | 1977-08-29 | 1980-05-20 | Eli Lilly And Company | Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids |
| US4166810A (en) * | 1978-04-20 | 1979-09-04 | Eli Lilly And Company | Derivatives of 4-desacetyl VLB C-3 carboxyhydrazide |
| US4199504A (en) * | 1978-05-15 | 1980-04-22 | Eli Lilly And Company | Bridged cathranthus alkaloid dimers |
| HU185691B (en) * | 1982-02-09 | 1985-03-28 | Richter Gedeon Vegyeszet | Process for preparing a new analgetic pharmaceutical composition |
| US4897477A (en) * | 1985-03-12 | 1990-01-30 | University Of Vermont & State Agricultural College | Synthesis of vinblastine and vincristine type compounds |
| US4841045A (en) * | 1985-03-12 | 1989-06-20 | University Of Vermont & State Agricultural College | Synthesis of vinblastine and vincristine type compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3352868A (en) * | 1964-04-01 | 1967-11-14 | Lilly Co Eli | Dihydrovinblastine |
| US3887565A (en) * | 1974-05-06 | 1975-06-03 | Lilly Co Eli | Vincadioline |
| FR2296418B1 (xx) * | 1974-12-30 | 1978-07-21 | Anvar | |
| US3944554A (en) * | 1975-01-09 | 1976-03-16 | Eli Lilly And Company | 4-Desacetoxy-3-hydroxyvinblastine |
-
1977
- 1977-03-30 US US05/782,644 patent/US4115388A/en not_active Expired - Lifetime
-
1978
- 1978-03-27 IL IL54357A patent/IL54357A/xx unknown
- 1978-03-28 CA CA299,833A patent/CA1097628A/en not_active Expired
- 1978-03-28 HU HU78EI787A patent/HU182482B/hu unknown
- 1978-03-28 DE DE19782813286 patent/DE2813286A1/de not_active Withdrawn
- 1978-03-28 NL NL7803253A patent/NL7803253A/xx not_active Application Discontinuation
- 1978-03-28 AR AR271569A patent/AR224342A1/es active
- 1978-03-28 GB GB11933/78A patent/GB1596235A/en not_active Expired
- 1978-03-29 IE IE610/78A patent/IE46692B1/en unknown
- 1978-03-29 BE BE1008790A patent/BE865406A/xx not_active IP Right Cessation
- 1978-03-29 FR FR7809052A patent/FR2385724A1/fr active Granted
- 1978-03-29 CH CH336578A patent/CH634849A5/de not_active IP Right Cessation
- 1978-03-29 IT IT21726/78A patent/IT1096161B/it active
- 1978-03-30 JP JP3801578A patent/JPS53130699A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2385724B1 (xx) | 1981-03-06 |
| CA1097628A (en) | 1981-03-17 |
| AR224342A1 (es) | 1981-11-30 |
| IT7821726A0 (it) | 1978-03-29 |
| FR2385724A1 (fr) | 1978-10-27 |
| GB1596235A (en) | 1981-08-19 |
| IT1096161B (it) | 1985-08-17 |
| NL7803253A (nl) | 1978-10-03 |
| IE46692B1 (en) | 1983-08-24 |
| IE780610L (en) | 1978-09-30 |
| IL54357A0 (en) | 1978-06-15 |
| CH634849A5 (de) | 1983-02-28 |
| BE865406A (fr) | 1978-09-29 |
| JPS53130699A (en) | 1978-11-14 |
| US4115388A (en) | 1978-09-19 |
| HU182482B (en) | 1984-01-30 |
| DE2813286A1 (de) | 1978-10-05 |
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