IT1060551B - Ammidi sostituite dell acido 3 metil 4 penil 3 butenoico aventi elevata azione ipolipemizzante - Google Patents

Ammidi sostituite dell acido 3 metil 4 penil 3 butenoico aventi elevata azione ipolipemizzante

Info

Publication number
IT1060551B
IT1060551B IT23797/74A IT2379774A IT1060551B IT 1060551 B IT1060551 B IT 1060551B IT 23797/74 A IT23797/74 A IT 23797/74A IT 2379774 A IT2379774 A IT 2379774A IT 1060551 B IT1060551 B IT 1060551B
Authority
IT
Italy
Prior art keywords
lipolipemizing
penyl
stars
methyl
action
Prior art date
Application number
IT23797/74A
Other languages
English (en)
Inventor
S Gorini
U Valcavi
Original Assignee
Lorenzini Sas Inst Biochim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lorenzini Sas Inst Biochim filed Critical Lorenzini Sas Inst Biochim
Priority to IT23797/74A priority Critical patent/IT1060551B/it
Priority to ZA00753659A priority patent/ZA753659B/xx
Priority to US05/584,490 priority patent/US4053635A/en
Priority to JP6867675A priority patent/JPS5616142B2/ja
Priority to SE7506576A priority patent/SE7506576L/xx
Priority to ES438350A priority patent/ES438350A1/es
Priority to DE2525848A priority patent/DE2525848C3/de
Priority to FR7518062A priority patent/FR2273520A1/fr
Priority to BE157185A priority patent/BE830063A/xx
Priority to GB2482675A priority patent/GB1475644A/en
Application granted granted Critical
Publication of IT1060551B publication Critical patent/IT1060551B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58—Preparation of carboxylic acid halides
    • C07C51/60—Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides or esters, lactones, salts into halides with the same carboxylic acid part

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT23797/74A 1974-06-10 1974-06-10 Ammidi sostituite dell acido 3 metil 4 penil 3 butenoico aventi elevata azione ipolipemizzante IT1060551B (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IT23797/74A IT1060551B (it) 1974-06-10 1974-06-10 Ammidi sostituite dell acido 3 metil 4 penil 3 butenoico aventi elevata azione ipolipemizzante
US05/584,490 US4053635A (en) 1974-06-10 1975-06-06 Substituted amides of 3-methyl-4-phenyl-3-butenoic acid, with a high hypolipemizing activity
ZA00753659A ZA753659B (en) 1974-06-10 1975-06-06 Substituted amides of 3-methyl-4-phenyl
SE7506576A SE7506576L (sv) 1974-06-10 1975-06-09 Forfarande for framstellning av 3-metyl-4-fenyl-3-butensyra.
JP6867675A JPS5616142B2 (it) 1974-06-10 1975-06-09
ES438350A ES438350A1 (es) 1974-06-10 1975-06-09 Procedimiento para la preparacion de amidas sustituidas de acido 3-metil-4-fenil-3-butenoico.
DE2525848A DE2525848C3 (de) 1974-06-10 1975-06-10 Substituierte Amide der 3-Methyl-4phenyl-3-butensäure, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
FR7518062A FR2273520A1 (fr) 1974-06-10 1975-06-10 Amides substitues de l'acide 3-methyl-4-phenyl-3-butenoique utilisables comme medicaments hypolipemisants, et procede pour leur preparation
BE157185A BE830063A (fr) 1974-06-10 1975-06-10 Amides substitues de l'acide 3-methyl-4-phenyl-3-butenoique a pouvoir hypolipemiant eleve
GB2482675A GB1475644A (en) 1974-06-10 1975-06-10 Substituted amides of 3-methyl-4-phenyl-3-butenoic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23797/74A IT1060551B (it) 1974-06-10 1974-06-10 Ammidi sostituite dell acido 3 metil 4 penil 3 butenoico aventi elevata azione ipolipemizzante

Publications (1)

Publication Number Publication Date
IT1060551B true IT1060551B (it) 1982-08-20

Family

ID=11210071

Family Applications (1)

Application Number Title Priority Date Filing Date
IT23797/74A IT1060551B (it) 1974-06-10 1974-06-10 Ammidi sostituite dell acido 3 metil 4 penil 3 butenoico aventi elevata azione ipolipemizzante

Country Status (10)

Country Link
US (1) US4053635A (it)
JP (1) JPS5616142B2 (it)
BE (1) BE830063A (it)
DE (1) DE2525848C3 (it)
ES (1) ES438350A1 (it)
FR (1) FR2273520A1 (it)
GB (1) GB1475644A (it)
IT (1) IT1060551B (it)
SE (1) SE7506576L (it)
ZA (1) ZA753659B (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4190674A (en) * 1976-02-03 1980-02-26 Burroughs Wellcome Co. 3-Fluoro-N-cyclopropylcinnamide

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2937117A (en) * 1953-06-19 1960-05-17 Chimie Atomistique Process for lowering high blood cholesterol levels
US3231469A (en) * 1961-03-18 1966-01-25 Istituto Biochimico Italiano beta-benzalbutyramide as an anticholesterolemic agent
US3245878A (en) * 1962-01-09 1966-04-12 Frank M Berger Methods for lowering blood cholesterol
US3626005A (en) * 1967-07-14 1971-12-07 Nat Distillers Chem Corp Preparation of unsaturated acyl halides
FR2040181A1 (it) * 1969-04-02 1971-01-22 Lipha
SE377113B (it) * 1971-05-15 1975-06-23 Ciba Geigy Ag
DE2205732A1 (de) * 1972-02-08 1973-08-16 Thomae Gmbh Dr K Neue 4-(4-biphenylyl)-butensaeurederivate

Also Published As

Publication number Publication date
US4053635A (en) 1977-10-11
DE2525848B2 (de) 1978-04-06
DE2525848C3 (de) 1978-11-30
FR2273520A1 (fr) 1976-01-02
JPS516938A (it) 1976-01-20
ZA753659B (en) 1976-05-26
BE830063A (fr) 1975-10-01
SE7506576L (sv) 1975-12-11
ES438350A1 (es) 1977-01-16
GB1475644A (en) 1977-06-01
DE2525848A1 (de) 1975-12-11
FR2273520B1 (it) 1980-05-23
JPS5616142B2 (it) 1981-04-14

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