IT1051557B - 1,1-dithienyl (3)-propane derivs - for treatment of heart and circula diseases - Google Patents

1,1-dithienyl (3)-propane derivs - for treatment of heart and circula diseases

Info

Publication number
IT1051557B
IT1051557B IT5307270A IT5307270A IT1051557B IT 1051557 B IT1051557 B IT 1051557B IT 5307270 A IT5307270 A IT 5307270A IT 5307270 A IT5307270 A IT 5307270A IT 1051557 B IT1051557 B IT 1051557B
Authority
IT
Italy
Prior art keywords
dithienyl
circula
derivs
propane
heart
Prior art date
Application number
IT5307270A
Other languages
Italian (it)
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Priority to IT5307270A priority Critical patent/IT1051557B/en
Priority to NL7015229A priority patent/NL151372B/en
Priority to SE7014443A priority patent/SE394280B/en
Priority to GB5498170A priority patent/GB1328545A/en
Priority to FR7103246A priority patent/FR2086133A2/en
Application granted granted Critical
Publication of IT1051557B publication Critical patent/IT1051557B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Cpds. are of formula (I) : (where AB = C(OH)CH2 or C=CH; R1 and R2 = H or 1-6C alkyl; R3 is H or OH, and R4 and R5 = H, hal, 1-6C alkyl opt. substd. by hal or 1-6C O-alkyl). They are prepd. by condensing a 3-thienylmetal cpd. with (II) : (where Y is Cl, Br, O-alkyl or 3-thienyl) and dehydrating the intermediate e.g. with SOCl2.
IT5307270A 1970-04-17 1970-08-27 1,1-dithienyl (3)-propane derivs - for treatment of heart and circula diseases IT1051557B (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
IT5307270A IT1051557B (en) 1970-08-27 1970-08-27 1,1-dithienyl (3)-propane derivs - for treatment of heart and circula diseases
NL7015229A NL151372B (en) 1970-08-27 1970-10-16 PROCESS FOR THE PREPARATION OF PREPARATIONS EFFECTIVE IN HEART AND CIRCULATION DISEASES, AND FOR THE PREPARATION OF COMPOUNDS, SUITABLE FOR USE IN THAT PROCESS.
SE7014443A SE394280B (en) 1970-04-17 1970-10-26 PROCEDURE FOR THE PRODUCTION OF BASIC SUBSTITUTED DITIENYL DERIVATIVES
GB5498170A GB1328545A (en) 1970-08-27 1970-11-19 Basic dithienyl derivatives
FR7103246A FR2086133A2 (en) 1970-04-17 1971-02-01 N-bis (3-thienylpropyl) phenethylamines -with coronary vasodilator - activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT5307270A IT1051557B (en) 1970-08-27 1970-08-27 1,1-dithienyl (3)-propane derivs - for treatment of heart and circula diseases

Publications (1)

Publication Number Publication Date
IT1051557B true IT1051557B (en) 1981-05-20

Family

ID=11279723

Family Applications (1)

Application Number Title Priority Date Filing Date
IT5307270A IT1051557B (en) 1970-04-17 1970-08-27 1,1-dithienyl (3)-propane derivs - for treatment of heart and circula diseases

Country Status (3)

Country Link
GB (1) GB1328545A (en)
IT (1) IT1051557B (en)
NL (1) NL151372B (en)

Also Published As

Publication number Publication date
GB1328545A (en) 1973-08-30
NL7015229A (en) 1972-02-29
NL151372B (en) 1976-11-15

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