IT1038094B - Composti eterociclici derivati dal benzo b tiofene e composizioni farmaceutiche dello stesso nonche procedimento per la preparazione dei derivati del benzo b tiofene - Google Patents
Composti eterociclici derivati dal benzo b tiofene e composizioni farmaceutiche dello stesso nonche procedimento per la preparazione dei derivati del benzo b tiofeneInfo
- Publication number
- IT1038094B IT1038094B IT23297/75A IT2329775A IT1038094B IT 1038094 B IT1038094 B IT 1038094B IT 23297/75 A IT23297/75 A IT 23297/75A IT 2329775 A IT2329775 A IT 2329775A IT 1038094 B IT1038094 B IT 1038094B
- Authority
- IT
- Italy
- Prior art keywords
- benzo
- thiofene
- thiophene
- derivatives
- procedure
- Prior art date
Links
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 title 2
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229930192474 thiophene Natural products 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2525674A GB1456323A (en) | 1974-06-06 | 1974-06-06 | Benzothiophenes process for preparing them and pharmaceutical compositions containing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IT1038094B true IT1038094B (it) | 1979-11-20 |
Family
ID=10224753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT23297/75A IT1038094B (it) | 1974-06-06 | 1975-05-14 | Composti eterociclici derivati dal benzo b tiofene e composizioni farmaceutiche dello stesso nonche procedimento per la preparazione dei derivati del benzo b tiofene |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4007204A (OSRAM) |
| JP (1) | JPS516958A (OSRAM) |
| AR (2) | AR207152A1 (OSRAM) |
| AT (1) | AT341517B (OSRAM) |
| BE (1) | BE829837A (OSRAM) |
| CA (1) | CA1030972A (OSRAM) |
| CH (1) | CH605910A5 (OSRAM) |
| DE (1) | DE2522655A1 (OSRAM) |
| DK (1) | DK135808B (OSRAM) |
| ES (1) | ES438303A1 (OSRAM) |
| FI (1) | FI751602A7 (OSRAM) |
| GB (1) | GB1456323A (OSRAM) |
| HU (1) | HU172820B (OSRAM) |
| IT (1) | IT1038094B (OSRAM) |
| NL (1) | NL7504921A (OSRAM) |
| NO (1) | NO751989L (OSRAM) |
| OA (1) | OA05022A (OSRAM) |
| SE (1) | SE7505482L (OSRAM) |
| SU (1) | SU578002A3 (OSRAM) |
| ZA (1) | ZA752871B (OSRAM) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU509682B2 (en) * | 1975-10-28 | 1980-05-22 | Eli Lilly And Company | 2-Aroyl-3-Phenylbenzothiophene Derivatives |
| US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
| US5175184A (en) * | 1982-10-19 | 1992-12-29 | Kotobuki Seiyaku Company Limited | Benzothiophene derivatives and antihyperuricemia thereof |
| NZ213986A (en) * | 1984-10-30 | 1989-07-27 | Usv Pharma Corp | Heterocyclic or aromatic compounds, and pharmaceutical compositions containing such |
| US4851554A (en) * | 1987-04-06 | 1989-07-25 | University Of Tennessee Research Corporation | Certain 3-substituted 2-alkyl benzofuran derivatives |
| US4806663A (en) * | 1987-04-06 | 1989-02-21 | The University Of Tennessee Research Corporation | Certain 3-substituted 2-alkyl benzofuran derivatives |
| US4912642A (en) * | 1987-09-03 | 1990-03-27 | The Boeing Company | Coordinated engine autothrottle |
| US4831156A (en) * | 1987-09-30 | 1989-05-16 | The University Of Tennessee Research Corp. | 3-substituted 2-alkyl indole derivatives |
| AU2543388A (en) * | 1987-09-30 | 1989-04-18 | University Of Tennessee Research Corporation, The | Certain 3-substituted 2-alkyl benzothiophene derivatives |
| JP3157882B2 (ja) * | 1991-11-15 | 2001-04-16 | 帝国臓器製薬株式会社 | 新規なベンゾチオフエン誘導体 |
| ES2173182T3 (es) * | 1994-04-11 | 2002-10-16 | Chugai Pharmaceutical Co Ltd | Derivado de 4,6-dl-butil-2,3-dihidrobenzotiofenos como antioxidantes de ldl. |
| CO4410191A1 (es) * | 1994-09-19 | 1997-01-09 | Lilly Co Eli | SINTESIS DE 3-[4-(2-AMINOETOXI)BENZOIL]-2-ARIL-6- HIDROXIBENZO [b] TIOFENOS |
| US6417199B1 (en) * | 1995-03-10 | 2002-07-09 | Eli Lilly And Company | 3-benzyl-benzothiophenes |
| US6653328B1 (en) * | 1995-03-10 | 2003-11-25 | Eli Lilly And Company | 3-benzyl-benzothiophenes |
| CA2236007A1 (en) * | 1995-10-31 | 1997-07-17 | Gerald Floyd Smith | Antithrombotic diamines |
| JP2000506885A (ja) * | 1996-03-19 | 2000-06-06 | イーライ・リリー・アンド・カンパニー | 3―[4―(2―アミノエトキシ)ベンゾイル]―2―アリール―6―ヒドロキシベンゾ[b]チオフェンの合成 |
| EP0980367A4 (en) | 1997-04-30 | 2003-03-19 | Lilly Co Eli | ANTITHROMBOTIC AGENTS |
| JP2002514217A (ja) | 1997-04-30 | 2002-05-14 | イーライ・リリー・アンド・カンパニー | 抗血栓物質 |
| KR20010020379A (ko) * | 1997-04-30 | 2001-03-15 | 피터 지. 스트링거 | 치환된 벤조[b]티오펜을 제조하기 위한 레지오선택적 알킬화 방법 |
| DE69824410T2 (de) | 1997-04-30 | 2005-06-02 | Eli Lilly And Co., Indianapolis | Antithrombosemittel |
| JP2002501503A (ja) | 1997-04-30 | 2002-01-15 | イーライ・リリー・アンド・カンパニー | 抗血栓症剤 |
| US6284756B1 (en) | 1998-04-30 | 2001-09-04 | Eli Lilly And Company | Antithrombotic agents |
| DK0997460T3 (da) * | 1998-10-28 | 2003-03-31 | Lilly Co Eli | Benzothiophenforbindelser som antithrombotiske midler og mellemprodukter |
| FR2864536B1 (fr) * | 2003-12-24 | 2006-03-17 | Clariant France Sa | Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre |
| EP2601958B1 (en) * | 2010-08-06 | 2017-03-29 | Tasly Pharmaceutical Group Co., Ltd. | Use of salvia miltiorrhiza composition in preparing drugs for secondary prevention of coronary heart disease |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3514465A (en) * | 1966-12-30 | 1970-05-26 | Degussa | Certain thiazolyl- and pyridinylaminoketones |
| US3706747A (en) * | 1970-06-05 | 1972-12-19 | Pfizer | Benzothieno(3,2-d)- and benzofuro(3,2-d)pyrimidines |
-
1974
- 1974-06-06 GB GB2525674A patent/GB1456323A/en not_active Expired
-
1975
- 1975-01-01 AR AR258913A patent/AR207152A1/es active
- 1975-04-21 US US05/569,819 patent/US4007204A/en not_active Expired - Lifetime
- 1975-04-25 NL NL7504921A patent/NL7504921A/xx not_active Application Discontinuation
- 1975-05-02 ZA ZA00752871A patent/ZA752871B/xx unknown
- 1975-05-13 SE SE7505482A patent/SE7505482L/xx unknown
- 1975-05-14 IT IT23297/75A patent/IT1038094B/it active
- 1975-05-22 DE DE19752522655 patent/DE2522655A1/de active Pending
- 1975-05-30 HU HU75LA00000867A patent/HU172820B/hu unknown
- 1975-05-30 FI FI751602A patent/FI751602A7/fi not_active Application Discontinuation
- 1975-06-04 DK DK251975AA patent/DK135808B/da unknown
- 1975-06-04 BE BE157003A patent/BE829837A/xx unknown
- 1975-06-05 SU SU7502143254A patent/SU578002A3/ru active
- 1975-06-05 NO NO751989A patent/NO751989L/no unknown
- 1975-06-06 AT AT431175A patent/AT341517B/de not_active IP Right Cessation
- 1975-06-06 JP JP50069021A patent/JPS516958A/ja active Pending
- 1975-06-06 CH CH730375A patent/CH605910A5/xx not_active IP Right Cessation
- 1975-06-06 OA OA55520A patent/OA05022A/xx unknown
- 1975-06-06 CA CA228,687A patent/CA1030972A/en not_active Expired
- 1975-06-06 ES ES438303A patent/ES438303A1/es not_active Expired
- 1975-11-07 AR AR261103A patent/AR210265A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| CA1030972A (en) | 1978-05-09 |
| DE2522655A1 (de) | 1975-12-18 |
| BE829837A (fr) | 1975-12-04 |
| AR210265A1 (es) | 1977-07-15 |
| US4007204A (en) | 1977-02-08 |
| AU8102275A (en) | 1976-11-11 |
| SU578002A3 (ru) | 1977-10-25 |
| AR207152A1 (es) | 1976-09-15 |
| DK135808B (da) | 1977-06-27 |
| SE7505482L (sv) | 1975-12-08 |
| ES438303A1 (es) | 1977-01-16 |
| DK135808C (OSRAM) | 1977-11-28 |
| CH605910A5 (OSRAM) | 1978-10-13 |
| GB1456323A (en) | 1976-11-24 |
| HU172820B (hu) | 1978-12-28 |
| ATA431175A (de) | 1977-06-15 |
| FI751602A7 (OSRAM) | 1975-12-07 |
| NO751989L (OSRAM) | 1975-12-09 |
| OA05022A (fr) | 1980-12-31 |
| NL7504921A (nl) | 1975-12-09 |
| AT341517B (de) | 1978-02-10 |
| DK251975A (OSRAM) | 1975-12-07 |
| JPS516958A (en) | 1976-01-20 |
| ZA752871B (en) | 1976-04-28 |
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