IT1036192B - PROCEDURE FOR THE MANUFACTURING OF A MONOLITHIC DRUG DELIVERING DEVICE - Google Patents

PROCEDURE FOR THE MANUFACTURING OF A MONOLITHIC DRUG DELIVERING DEVICE

Info

Publication number
IT1036192B
IT1036192B IT68466/75A IT6846675A IT1036192B IT 1036192 B IT1036192 B IT 1036192B IT 68466/75 A IT68466/75 A IT 68466/75A IT 6846675 A IT6846675 A IT 6846675A IT 1036192 B IT1036192 B IT 1036192B
Authority
IT
Italy
Prior art keywords
procedure
manufacturing
delivering device
drug delivering
monolithic drug
Prior art date
Application number
IT68466/75A
Other languages
Italian (it)
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of IT1036192B publication Critical patent/IT1036192B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT68466/75A 1974-06-07 1975-06-06 PROCEDURE FOR THE MANUFACTURING OF A MONOLITHIC DRUG DELIVERING DEVICE IT1036192B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US477297A US3923939A (en) 1974-06-07 1974-06-07 Process for improving release kinetics of a monolithic drug delivery device

Publications (1)

Publication Number Publication Date
IT1036192B true IT1036192B (en) 1979-10-30

Family

ID=23895337

Family Applications (1)

Application Number Title Priority Date Filing Date
IT68466/75A IT1036192B (en) 1974-06-07 1975-06-06 PROCEDURE FOR THE MANUFACTURING OF A MONOLITHIC DRUG DELIVERING DEVICE

Country Status (10)

Country Link
US (1) US3923939A (en)
JP (1) JPS6043327B2 (en)
CA (1) CA1047403A (en)
CH (1) CH611160A5 (en)
DE (1) DE2525061C2 (en)
FR (1) FR2273515A1 (en)
GB (1) GB1477545A (en)
IT (1) IT1036192B (en)
MX (1) MX3007E (en)
SE (1) SE405803B (en)

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HU174057B (en) * 1976-09-17 1979-10-28 Richter Gedeon Vegyeszet Coating material for the regulated release of the active substance in biologically active preparations and process for preparing such preparations with regulated release of the active substance
US4190642A (en) * 1978-04-17 1980-02-26 Alza Corporation Ocular therapeutic system for dispensing a medication formulation
US4156604A (en) * 1978-09-15 1979-05-29 Minnesota Mining And Manufacturing Company Controlled delivery of corrosion inhibitors for silver recovery cartridges
US4333850A (en) * 1979-06-15 1982-06-08 Borg-Warner Corporation Filled polymer composition for automatic addition of a corrosion inhibitor to a coolant system
US4304765A (en) * 1980-10-14 1981-12-08 Alza Corporation Ocular insert housing steroid in two different therapeutic forms
US4432964A (en) * 1981-08-24 1984-02-21 Alza Corporation Topical composition containing steroid in two forms released independently from polymeric carrier
DE3218150C2 (en) * 1982-05-14 1986-09-25 Akzo Gmbh, 5600 Wuppertal Active substance-containing body for long-term release and process for its production
JPS5931701A (en) * 1982-08-16 1984-02-20 Nitto Electric Ind Co Ltd Membrane containing liquid active substance and its preparation
US4557925A (en) * 1982-07-08 1985-12-10 Ab Ferrosan Membrane-coated sustained-release tablets and method
US4478818A (en) * 1982-12-27 1984-10-23 Alza Corporation Ocular preparation housing steroid in two different therapeutic forms
US4564364A (en) * 1983-05-26 1986-01-14 Alza Corporation Active agent dispenser
GB8331546D0 (en) * 1983-11-25 1984-01-04 Exxon Research Engineering Co Polymeric compositions
US4624848A (en) * 1984-05-10 1986-11-25 Ciba-Geigy Corporation Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use
US4725439A (en) * 1984-06-29 1988-02-16 Alza Corporation Transdermal drug delivery device
US4704282A (en) * 1984-06-29 1987-11-03 Alza Corporation Transdermal therapeutic system having improved delivery characteristics
US4629619A (en) * 1984-09-05 1986-12-16 Ab Ferrosan Membrane-coated sustained-release tablets and method
US4629620A (en) * 1984-09-05 1986-12-16 Ab Ferrosan Membrane-coated sustained-release tablets and method
AU592546B2 (en) * 1984-12-03 1990-01-18 Baxter International Inc. Drug delivery apparatus preventing local and systemic toxicity
US4874366A (en) * 1984-12-03 1989-10-17 Baxter Internatiional Inc. Housing enabling passive mixing of a beneficial agent with a diluent
US4666704A (en) * 1985-05-24 1987-05-19 International Minerals & Chemical Corp. Controlled release delivery system for macromolecules
US4898733A (en) * 1985-11-04 1990-02-06 International Minerals & Chemical Corp. Layered, compression molded device for the sustained release of a beneficial agent
DE3775830D1 (en) * 1986-06-13 1992-02-20 Alza Corp ACTIVATING A TRANSDERMAL DRUG DELIVERY SYSTEM THROUGH MOISTURE.
US4908027A (en) * 1986-09-12 1990-03-13 Alza Corporation Subsaturated transdermal therapeutic system having improved release characteristics
US5344656A (en) * 1986-09-12 1994-09-06 Alza Corporation Subsaturated transdermal therapeutic system having improved release characteristics
US4761289A (en) * 1986-10-10 1988-08-02 International Minerals & Chemical Corp. Sustained release implant and method for preparing same
US5071656A (en) * 1987-03-05 1991-12-10 Alza Corporation Delayed onset transdermal delivery device
DE3743945A1 (en) * 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg DEVICE FOR DELIVERING SUBSTANCES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE
US4917895A (en) * 1987-11-02 1990-04-17 Alza Corporation Transdermal drug delivery device
US4837027A (en) * 1987-11-09 1989-06-06 Alza Corporation Transdermal drug delivery device
US4781924A (en) * 1987-11-09 1988-11-01 Alza Corporation Transdermal drug delivery device
US5229148A (en) * 1989-04-19 1993-07-20 Wm. Wrigley Jr. Company Method of combining active ingredients with polyvinyl acetates
US4978537A (en) * 1989-04-19 1990-12-18 Wm. Wrigley Jr. Company Gradual release structures for chewing gum
US5198251A (en) * 1989-04-19 1993-03-30 Wm. Wrigley Jr. Company Gradual release structures for chewing gum
US5154939A (en) * 1989-04-19 1992-10-13 Wm. Wrigley Jr. Company Use of salt to improve extrusion encapsulation of chewing gum ingredients
US5165944A (en) * 1989-04-19 1992-11-24 Wm. Wrigley Jr. Company Gradual release structures for chewing gum
US5108762A (en) * 1989-04-19 1992-04-28 Wm. Wrigley Jr. Company Gradual release structures for chewing gum
US5091186A (en) * 1989-08-15 1992-02-25 Cygnus Therapeutic Systems Biphasic transdermal drug delivery device
US5124157A (en) * 1989-08-18 1992-06-23 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
AU639645B2 (en) * 1989-10-10 1993-07-29 Wm. Wrigley Jr. Company Gradual release structures made from fiber spinning techniques
JPH03287525A (en) * 1990-04-03 1991-12-18 Toichi Chikuma Applicable analgesic tool
US5508038A (en) * 1990-04-16 1996-04-16 Alza Corporation Polyisobutylene adhesives for transdermal devices
JPH0421521U (en) * 1990-06-14 1992-02-24
US5128155A (en) * 1990-12-20 1992-07-07 Wm. Wrigley Jr. Company Flavor releasing structures for chewing gum
US5271736A (en) * 1991-05-13 1993-12-21 Applied Medical Research Collagen disruptive morphology for implants
ES2096103T3 (en) * 1992-01-13 1997-03-01 Pfizer PREPARATION OF INCREASED RESISTANCE TABLETS.
US5443505A (en) * 1993-11-15 1995-08-22 Oculex Pharmaceuticals, Inc. Biocompatible ocular implants
US5962011A (en) * 1993-12-06 1999-10-05 Schering-Plough Healthcare Products, Inc. Device for delivery of dermatological ingredients
US5633000A (en) * 1994-06-23 1997-05-27 Axxia Technologies Subcutaneous implant
US5819742A (en) * 1996-11-06 1998-10-13 Family Health International Vaginal device for preventing conception or the transmission of sexually transmitted diseases, or both
ATE203157T1 (en) * 1996-12-20 2001-08-15 Alza Corp INJECTABLE DEPOSIT GEL PREPARATION AND PRODUCTION METHOD
US6039968A (en) * 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
US6110500A (en) * 1998-03-25 2000-08-29 Temple University Coated tablet with long term parabolic and zero-order release kinetics
IL135061A0 (en) * 2000-03-14 2001-05-20 Ahron Jodaikin Strategic targeted fluoridation and chemical treatment of teeth
US20050175959A1 (en) * 2000-03-14 2005-08-11 Coll Partners Ltd. System for the controlled delivery of an active material to a dental site
US20030211974A1 (en) * 2000-03-21 2003-11-13 Brodbeck Kevin J. Gel composition and methods
EP1322235B2 (en) * 2000-09-29 2010-08-11 Cordis Corporation Coated medical devices
US20030157178A1 (en) * 2001-11-14 2003-08-21 Guohua Chen Injectable depot composition
IL162001A0 (en) 2001-11-14 2005-11-20 Alza Corp Catheter injectable depot compositions and uses thereof
PT2561860T (en) * 2002-05-31 2018-05-08 Titan Pharmaceuticals Inc Implantable polymeric device for sustained release of buprenorphine
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
EP2030611A1 (en) 2002-07-31 2009-03-04 Alza Corporation Injectable multimodal polymer depot compositions and uses thereof
KR20050038008A (en) 2002-07-31 2005-04-25 알자 코포레이션 Injectable depot compositions and uses thereof
EP1610791B1 (en) * 2003-03-31 2011-02-23 Titan Pharmaceuticals, Inc. Implantable polymeric device for sustained release of dopamine agonist
US7850453B2 (en) * 2007-08-08 2010-12-14 Coll Partners Ltd. Reshapable device for fixation at a dental site
USRE48948E1 (en) * 2008-04-18 2022-03-01 Warsaw Orthopedic, Inc. Clonidine compounds in a biodegradable polymer
RU2011138947A (en) * 2009-02-23 2013-03-27 Клт Инк. LACRIMAL IMPLANTS AND RELATED WAYS
JP5886204B2 (en) * 2009-10-30 2016-03-16 アトーン ファルマ、インコーポレイテッドＡｔｏｎ Ｐｈａｒｍａ，Ｉｎｃ． Intraocular drug delivery device
US9138308B2 (en) 2010-02-03 2015-09-22 Apollo Endosurgery, Inc. Mucosal tissue adhesion via textured surface
US9205577B2 (en) * 2010-02-05 2015-12-08 Allergan, Inc. Porogen compositions, methods of making and uses
ES2623475T3 (en) * 2010-05-11 2017-07-11 Allergan, Inc. Porogen compositions, methods for making them and uses
US9668844B2 (en) 2013-11-06 2017-06-06 Colldent Y.A Ltd Device for fixation at a dental site
CA2931547A1 (en) 2013-12-09 2015-06-18 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
KR20220140711A (en) 2020-01-13 2022-10-18 듀렉트 코퍼레이션 Reduced Impurity Sustained Release Drug Delivery Systems and Related Methods

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US3402240A (en) * 1957-06-25 1968-09-17 Pfizer & Co C Medicinal tablet and process of making same
US3639583A (en) * 1968-06-28 1972-02-01 Goodrich Co B F Biocidal elastomeric compositions
US3700380A (en) * 1970-10-01 1972-10-24 Tecna Corp Surface or lining compatible with blood or other tissue
GB1412983A (en) * 1971-11-30 1975-11-05 Debell & Richardson Method of producing porous plastic materials
FR2183546B1 (en) * 1972-05-10 1975-06-20 Servier Lab
JPS49118827A (en) * 1973-03-27 1974-11-13
JPS506709A (en) * 1973-05-18 1975-01-23

Also Published As

Publication number Publication date
DE2525061C2 (en) 1985-08-22
CH611160A5 (en) 1979-05-31
JPS6043327B2 (en) 1985-09-27
SE405803B (en) 1979-01-08
GB1477545A (en) 1977-06-22
FR2273515B1 (en) 1980-02-15
MX3007E (en) 1980-01-28
US3923939A (en) 1975-12-02
DE2525061A1 (en) 1976-01-02
JPS5112920A (en) 1976-01-31
FR2273515A1 (en) 1976-01-02
CA1047403A (en) 1979-01-30
SE7506099L (en) 1975-12-08

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