IS7666A - N-súlfónýlpíperídín sem málmprótínkljúfatálmar (TACE) - Google Patents

N-súlfónýlpíperídín sem málmprótínkljúfatálmar (TACE)

Info

Publication number
IS7666A
IS7666A IS7666A IS7666A IS7666A IS 7666 A IS7666 A IS 7666A IS 7666 A IS7666 A IS 7666A IS 7666 A IS7666 A IS 7666A IS 7666 A IS7666 A IS 7666A
Authority
IS
Iceland
Prior art keywords
sulphonylpiperidine
tace
chelation
inhibitors
metal protein
Prior art date
Application number
IS7666A
Other languages
English (en)
Inventor
Nicholas Burrows Jeremy
Tucker Howard
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of IS7666A publication Critical patent/IS7666A/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/96Sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IS7666A 2002-07-13 2005-01-26 N-súlfónýlpíperídín sem málmprótínkljúfatálmar (TACE) IS7666A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0216379.8A GB0216379D0 (en) 2002-07-13 2002-07-13 Compounds
PCT/GB2003/002959 WO2004006925A1 (en) 2002-07-13 2003-07-09 N-sulfonylpiperidines as metalloproteinase inhibitors (tace)

Publications (1)

Publication Number Publication Date
IS7666A true IS7666A (is) 2005-01-26

Family

ID=9940460

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7666A IS7666A (is) 2002-07-13 2005-01-26 N-súlfónýlpíperídín sem málmprótínkljúfatálmar (TACE)

Country Status (16)

Country Link
US (1) US20060142336A1 (is)
EP (1) EP1534281A1 (is)
JP (1) JP2005536501A (is)
CN (1) CN1681504A (is)
AU (1) AU2003254436A1 (is)
BR (1) BR0312614A (is)
CA (1) CA2492083A1 (is)
GB (1) GB0216379D0 (is)
IL (1) IL166009A0 (is)
IS (1) IS7666A (is)
MX (1) MXPA05000518A (is)
NO (1) NO20050765L (is)
PL (1) PL375304A1 (is)
RU (1) RU2004138547A (is)
WO (1) WO2004006925A1 (is)
ZA (1) ZA200500209B (is)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2459380C (en) 2001-09-07 2010-11-23 Kaken Pharmaceutical Co., Ltd. Reverse hydroxamic acid derivatives
NZ587799A (en) 2008-03-25 2012-06-29 Affectis Pharmaceuticals Ag Novel p2x7r antagonists and their use
CN102395562A (zh) 2009-04-14 2012-03-28 阿费克蒂斯制药股份公司 新的p2x7r拮抗剂及其用途
WO2012110190A1 (en) 2011-02-17 2012-08-23 Affectis Pharmaceuticals Ag Novel p2x7r antagonists and their use
WO2012163792A1 (en) 2011-05-27 2012-12-06 Affectis Pharmaceuticals Ag Novel p2x7r antagonists and their use
WO2012163456A1 (en) 2011-05-27 2012-12-06 Affectis Pharmaceuticals Ag Novel p2x7r antagonists and their use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1087937A1 (en) * 1998-06-17 2001-04-04 Du Pont Pharmaceuticals Company Cyclic hydroxamic acids as metalloproteinase inhibitors
EP1107953A1 (en) * 1998-08-29 2001-06-20 British Biotech Pharmaceuticals Limited Hydroxamic acid derivatives as proteinase inhibitors
GB9919776D0 (en) * 1998-08-31 1999-10-27 Zeneca Ltd Compoujnds
WO2000044723A1 (en) * 1999-01-27 2000-08-03 American Cyanamid Company Alkynyl containing hydroxamic acid derivatives, their preparation and their use as matrix metalloproteinase (mmp) inhibitors/tnf-alpha converting enzyme (tace) inhibitors

Also Published As

Publication number Publication date
US20060142336A1 (en) 2006-06-29
CN1681504A (zh) 2005-10-12
IL166009A0 (en) 2006-01-15
RU2004138547A (ru) 2005-08-20
BR0312614A (pt) 2005-05-10
JP2005536501A (ja) 2005-12-02
ZA200500209B (en) 2005-11-02
PL375304A1 (en) 2005-11-28
AU2003254436A1 (en) 2004-02-02
NO20050765L (no) 2005-04-13
WO2004006925A1 (en) 2004-01-22
EP1534281A1 (en) 2005-06-01
CA2492083A1 (en) 2004-01-22
GB0216379D0 (en) 2002-08-21
MXPA05000518A (es) 2005-03-23

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