IS7567A - 1-oxa-díbensóasúlen sem latar æxlisdrepþáttar framleiðslu og milliefni til framleiðslu á þeim - Google Patents

1-oxa-díbensóasúlen sem latar æxlisdrepþáttar framleiðslu og milliefni til framleiðslu á þeim

Info

Publication number
IS7567A
IS7567A IS7567A IS7567A IS7567A IS 7567 A IS7567 A IS 7567A IS 7567 A IS7567 A IS 7567A IS 7567 A IS7567 A IS 7567A IS 7567 A IS7567 A IS 7567A
Authority
IS
Iceland
Prior art keywords
production
dibenzoazulene
oxa
intermediates
necrosis factor
Prior art date
Application number
IS7567A
Other languages
English (en)
Inventor
Mercep Mladen
Mesic Milan
Pesic Dijana
Original Assignee
Pliva-Istrazivacki Institut D.O.O.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva-Istrazivacki Institut D.O.O. filed Critical Pliva-Istrazivacki Institut D.O.O.
Publication of IS7567A publication Critical patent/IS7567A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
IS7567A 2002-05-21 2004-11-29 1-oxa-díbensóasúlen sem latar æxlisdrepþáttar framleiðslu og milliefni til framleiðslu á þeim IS7567A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HR20020441A HRP20020441A2 (en) 2002-05-21 2002-05-21 1-oxa-dibenzoazulen as inhibitor of production of tumor necrosis factors and intermediate for preparation thereof
PCT/HR2003/000024 WO2003097649A2 (en) 2002-05-21 2003-05-20 1-oxa-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof

Publications (1)

Publication Number Publication Date
IS7567A true IS7567A (is) 2004-11-29

Family

ID=29433923

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7567A IS7567A (is) 2002-05-21 2004-11-29 1-oxa-díbensóasúlen sem latar æxlisdrepþáttar framleiðslu og milliefni til framleiðslu á þeim

Country Status (13)

Country Link
US (2) US20050209214A1 (is)
EP (1) EP1506204A2 (is)
JP (1) JP2005532327A (is)
CN (1) CN1315838C (is)
AR (1) AR040087A1 (is)
AU (1) AU2003232371A1 (is)
CA (1) CA2485214A1 (is)
HK (1) HK1081950A1 (is)
HR (1) HRP20020441A2 (is)
IS (1) IS7567A (is)
PL (1) PL374398A1 (is)
RS (1) RS99404A (is)
WO (1) WO2003097649A2 (is)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20020304B1 (en) * 2002-04-10 2008-04-30 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 1-oxa-3-aza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the production thereof
HRP20030160A2 (en) * 2003-03-06 2005-04-30 Pliva-Istra�iva�ki institut d.o.o. 1-thiadibenzoazulene derivatives and biological action thereof
HRP20030955A2 (en) * 2003-11-21 2005-08-31 Pliva-Istra�iva�ki institut d.o.o. USE OF 1-OXADIBENZO[e,h]AZULENES FOR THE MANUFACTURE OF PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT AND PREVENTION OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS
US8022102B2 (en) * 2004-06-23 2011-09-20 Janssen Pharmaceutica, Nv Unsaturated tetracyclic tetrahydrofuran derivatives
JP2008532927A (ja) * 2005-01-13 2008-08-21 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 抗炎症マクロライド接合体
WO2006101937A1 (en) 2005-03-18 2006-09-28 Janssen Pharmaceutica N.V. Acylhydrazones as kinase modulators

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH532038A (de) * 1970-05-25 1972-12-31 Ciba Geigy Ag Verfahren zur Herstellung von neuen Cycloheptenderivaten
US3859439A (en) * 1970-05-26 1975-01-07 Ciba Geigy Corp 2,3-dihydro-5 -trifluoromethyl-1h-dibenzo(2,3:6,7) thiepino (4,5-c) pyrroles as cns-depressants
US3711489A (en) * 1971-03-31 1973-01-16 Pfizer Certain 8,9-dihydro(3,4,7,8)cycloocta(1,2-d)imidazoles
US4112110A (en) * 1974-02-22 1978-09-05 Ciba-Geigy Corporation Oxygenated azatetracyclic compounds
US3974285A (en) * 1974-04-10 1976-08-10 Merck & Co., Inc. 10,11-Furo-derivatives of cyproheptadine
US3894032A (en) * 1974-04-10 1975-07-08 Merck & Co Inc 10,11-Furo derivatives of cyproheptadine
US4044143A (en) * 1975-01-30 1977-08-23 Merck & Co., Inc. 10,11-Bis-(hydroxyalkyl) derivatives of cyproheptadine
US4271179A (en) * 1976-05-24 1981-06-02 Akzona Incorporated 1,2,3,3a,8,12b-Hexahydro-dibenzo[1,2;5,6]cyclohepta[3,4-C]pyrroles and pharmaceutical use thereof
NL7605526A (nl) * 1976-05-24 1977-11-28 Akzo Nv Nieuwe tetracyclische derivaten.
US4198421A (en) * 1978-11-30 1980-04-15 E. I. Du Pont De Nemours And Company Antiinflammatory 2-substituted-dibenzo[2,3:6,7]oxepino[4,5-d]imidazoles
US4267184A (en) * 1979-02-08 1981-05-12 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-2-(substituted-thio)pyrroles and their corresponding sulfoxides and sulfones
US4267190A (en) * 1980-04-18 1981-05-12 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-α,α-bis(polyfluoromethyl)-1H-pyrrole-2-methanethiols
US5840749A (en) * 1989-08-25 1998-11-24 Hoechst Marion Roussel, Inc. N-hydroxy-dibenz b,e!oxepinalkylamines, N-hydroxy-dibenz b,e!oxepinalkanoic acid amides and related heterocyclic analogues
EP0887339A1 (de) * 1997-06-27 1998-12-30 Roche Diagnostics GmbH Neue Azulenderivate und diese enthaltende Arzneimittel
UA52778C2 (uk) * 1997-10-10 2003-01-15 Янссен Фармацевтика Н.В. Галогенозаміщені тетрациклічні похідні тетрагідрофурану, спосіб їх отримання та композиція на їх основі
HRP20000310A2 (en) * 2000-05-17 2002-02-28 Pliva Farmaceutska Ind Dioniko New dibenzoazulene compounds as tumor necrosis factor inhibitors
HRP20020440B1 (en) * 2002-05-21 2008-02-29 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 1-aza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof

Also Published As

Publication number Publication date
HK1081950A1 (en) 2006-05-26
US20050148577A1 (en) 2005-07-07
US20050209214A1 (en) 2005-09-22
RS99404A (en) 2006-10-27
HRP20020441A2 (en) 2003-12-31
WO2003097649A3 (en) 2004-04-29
JP2005532327A (ja) 2005-10-27
AU2003232371A1 (en) 2003-12-02
WO2003097649A2 (en) 2003-11-27
CA2485214A1 (en) 2003-11-27
PL374398A1 (en) 2005-10-17
CN1315838C (zh) 2007-05-16
AR040087A1 (es) 2005-03-16
CN1665821A (zh) 2005-09-07
EP1506204A2 (en) 2005-02-16
AU2003232371A8 (en) 2003-12-02

Similar Documents

Publication Publication Date Title
NO20031776L (no) Null-boringskomplettering og produksjonssystem
DK1523512T3 (da) Polyimide-aerogeler, carbon-aerogeler, og metalcar-bidaerogeler og fremgangsmåder til fremstilling af samme
IS7520A (is) Pyrimidínonefnasambönd, samsetningar og aðferðir
EP1845970A4 (en) INHIBITORS OF TUMOR NECROSIS FACTOR
NO20044588L (no) Nye forbindelser
NO20044432L (no) Nye forbindelser
DK1628749T3 (da) Anordninger og fremgangsmåder til biomateriel produktion
DE50303193D1 (de) Übertrager
IS2775B (is) Sambrædd pýrrólókarbasól og aðferðir við framleiðslu þeirra
IS7351A (is) Kristölluð karvedílól á föstu formi og aðferðir til að framleiða þau
HK1081953A1 (en) 1-Aza-dibenzoazolenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof
DE60330946D1 (de) Zellularer fernsprecher
EP1693369A4 (en) INHIBITOR FOR PRODUCTION OF PROTEIN MODIFIERS
DE60302741D1 (de) Grillgerät
DE60328948D1 (de) Magnetron
DE60329814D1 (de) Drosselspule
IS7568A (is) 1,3-díasa-díbensóasúlen sem latar æxlisdrepþáttarframleiðslu og milliefni til framleiðslu á þeim
IS7567A (is) 1-oxa-díbensóasúlen sem latar æxlisdrepþáttar framleiðslu og milliefni til framleiðslu á þeim
HK1081949A1 (en) 1-Thia-3-aza-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof
DE60321080D1 (de) Magnetron
IS7565A (is) 1,2-díasa-díbensóasúlen sem latar æxlisdrepþáttarframleiðslu og milliefni til framleiðslu á þeim
DE60308109D1 (de) Magnetron
DE50310824D1 (de) Bohrkopf
DE60324637D1 (de) Rohrstutzen und dessen Herstellungsverfahren
IS7339A (is) Aðferð til framleiðslu á 7alfa-metýlsterum