IS7260A - Nýmyndun og hreinsun valasýklóvírs - Google Patents

Nýmyndun og hreinsun valasýklóvírs

Info

Publication number
IS7260A
IS7260A IS7260A IS7260A IS7260A IS 7260 A IS7260 A IS 7260A IS 7260 A IS7260 A IS 7260A IS 7260 A IS7260 A IS 7260A IS 7260 A IS7260 A IS 7260A
Authority
IS
Iceland
Prior art keywords
valacyclovir
purification
synthesis
Prior art date
Application number
IS7260A
Other languages
English (en)
Icelandic (is)
Inventor
Yu Etinger Marina
M. Yudovich Lev
Yuzefovich Michael
A. Nisnevich Gennady
Zion Dolitzky Ben
Pertsikov Boris
Tishin Boris
Blasberger Dina
Original Assignee
Teva Pharmaceutical Industries Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceutical Industries Ltd. filed Critical Teva Pharmaceutical Industries Ltd.
Publication of IS7260A publication Critical patent/IS7260A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
IS7260A 2001-11-14 2004-05-11 Nýmyndun og hreinsun valasýklóvírs IS7260A (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33280201P 2001-11-14 2001-11-14
US34227301P 2001-12-21 2001-12-21
PCT/US2002/036269 WO2003041647A2 (en) 2001-11-14 2002-11-13 Synthesis and purification of valacyclovir

Publications (1)

Publication Number Publication Date
IS7260A true IS7260A (is) 2004-05-11

Family

ID=26988392

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7260A IS7260A (is) 2001-11-14 2004-05-11 Nýmyndun og hreinsun valasýklóvírs

Country Status (14)

Country Link
US (2) US6849737B2 (cg-RX-API-DMAC7.html)
EP (1) EP1465894A4 (cg-RX-API-DMAC7.html)
JP (1) JP2005508993A (cg-RX-API-DMAC7.html)
KR (2) KR20050044449A (cg-RX-API-DMAC7.html)
CN (1) CN1307177C (cg-RX-API-DMAC7.html)
CA (2) CA2649826A1 (cg-RX-API-DMAC7.html)
HR (1) HRP20040511A2 (cg-RX-API-DMAC7.html)
IL (1) IL161969A0 (cg-RX-API-DMAC7.html)
IN (1) IN2007DE04250A (cg-RX-API-DMAC7.html)
IS (1) IS7260A (cg-RX-API-DMAC7.html)
MX (1) MX242714B (cg-RX-API-DMAC7.html)
NO (1) NO20042433L (cg-RX-API-DMAC7.html)
PL (1) PL371732A1 (cg-RX-API-DMAC7.html)
WO (1) WO2003041647A2 (cg-RX-API-DMAC7.html)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL374179A1 (en) * 2001-09-07 2005-10-03 Teva Pharmaceutical Industries Ltd. Crystalline forms of valacyclovir hydrochloride
JP2005511612A (ja) * 2001-11-05 2005-04-28 グラクソ　グループ　リミテッド 塩酸バラシクロビルの無水結晶形
IL161969A0 (en) * 2001-11-14 2005-11-20 Teva Pharma Synthesis and purification of valacyclovir
US20050043329A1 (en) * 2002-09-06 2005-02-24 Shlomit Wizel Crystalline forms of valacyclovir hydrochloride
US20050059684A1 (en) * 2002-10-16 2005-03-17 Ben-Zion Dolitzky Method for reducing residual alcohols in crystalline valacyclovir hydrochloride
AU2003277433A1 (en) * 2002-10-16 2004-05-04 Teva Pharmaceutical Industries Ltd. Method for reducing residual alcohols in crystalline valacyclovir hydrochloride
WO2004052892A1 (en) * 2002-12-09 2004-06-24 Texcontor Etablissement Anhydrous crystalline form of valacyclovir hydrochloride
EP1633753A1 (en) * 2003-05-30 2006-03-15 EOS Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ti Caret A.S. Novel crystalline forms of valacyclovir hydrochloride
KR100871621B1 (ko) * 2003-06-02 2008-12-02 테바 파마슈티컬 인더스트리즈 리미티드 발라시클로비르 히드로클로라이드의 신규한 결정질 형태
KR20060117355A (ko) * 2004-01-21 2006-11-16 테바 파마슈티컬 인더스트리즈 리미티드 발라시클로버 염산염의 제조 방법
CA2572268A1 (en) * 2004-06-30 2006-02-02 Teva Pharmaceutical Industries Ltd. Method for reducing residual alcohols in crystalline valacyclovir hydrochloride
CN101068814A (zh) * 2004-09-04 2007-11-07 特瓦制药工业有限公司 分离的伐昔洛韦杂质，制备伐昔洛韦杂质的方法及其作为参比标准物的应用
US7958087B2 (en) * 2004-11-17 2011-06-07 Iron Mountain Incorporated Systems and methods for cross-system digital asset tag propagation
EP1746098A1 (en) * 2005-07-21 2007-01-24 SOLMAG S.p.A. Valacyclovir polymorphs and a process for the preparation thereof
US20070112193A1 (en) * 2005-11-14 2007-05-17 Khunt Mayur D Valacyclovir process
GB0605344D0 (en) * 2006-03-17 2006-04-26 Pliva Istrazivanje I Razvoj D Pharmaceutically acceptable salts and polymorphic forms
CN1903854B (zh) * 2006-08-09 2012-05-23 丽珠医药集团股份有限公司 一种合成盐酸伐昔洛韦的方法
WO2008139539A1 (ja) * 2007-04-27 2008-11-20 Ajinomoto Co., Inc. バラシクロビルの製造方法
US20080281099A1 (en) * 2007-05-07 2008-11-13 Mayur Devjibhai Khunt Process for purifying valacyclovir hydrochloride and intermediates thereof
CN102584825B (zh) * 2011-01-17 2014-04-02 四川科伦药物研究有限公司 一种合成盐酸伐昔洛韦的方法
WO2017149420A1 (en) * 2016-03-03 2017-09-08 Aurobindo Pharma Ltd Process for the preparation of valacyclovir
CN106632335A (zh) * 2016-12-27 2017-05-10 河南康达制药有限公司 一种盐酸伐昔洛韦的制备方法
CN114621227B (zh) * 2022-02-28 2024-07-09 海南久常制药有限公司 一种盐酸伐昔洛韦、制剂及其制备方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4199574A (en) 1974-09-02 1980-04-22 Burroughs Wellcome Co. Methods and compositions for treating viral infections and guanine acyclic nucleosides
GB8719367D0 (en) 1987-08-15 1987-09-23 Wellcome Found Therapeutic compounds
ATE199719T1 (de) * 1993-06-10 2001-03-15 Rolabo Sl Verfahren zur herstellung von aminosäureester von nukleosid analogen
GB9501178D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Guanine derivative
GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet
US6117453A (en) * 1995-04-14 2000-09-12 Pharma Pass Solid compositions containing polyethylene oxide and an active ingredient
US5672243A (en) * 1995-11-28 1997-09-30 Mosel Vitelic, Inc. Antireflection coating for highly reflective photolithographic layers comprising chromium oxide or chromium suboxide
DK0874631T3 (da) * 1996-01-19 2004-03-22 Glaxo Group Ltd Anvendelse af valaciclovir til fremstilling af et medikament til behandling af genital herpes ved en enkelt daglig anvendelse
US6040446A (en) * 1996-01-26 2000-03-21 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
US5756736A (en) * 1996-01-26 1998-05-26 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
IT1283447B1 (it) * 1996-07-18 1998-04-21 Ind Chimica Srl Processo di preparazione del valaciclovir e relativi intermedi
AU735438B2 (en) * 1996-11-12 2001-07-05 Medivir Ab Nucleosides
PL374179A1 (en) * 2001-09-07 2005-10-03 Teva Pharmaceutical Industries Ltd. Crystalline forms of valacyclovir hydrochloride
JP2005511612A (ja) * 2001-11-05 2005-04-28 グラクソ　グループ　リミテッド 塩酸バラシクロビルの無水結晶形
IL161969A0 (en) * 2001-11-14 2005-11-20 Teva Pharma Synthesis and purification of valacyclovir
US20060147519A1 (en) * 2002-06-24 2006-07-06 Ashish Gogia Process for the preparation of robust formulations of valacyclovir hydrochloride tablets
US20050043329A1 (en) * 2002-09-06 2005-02-24 Shlomit Wizel Crystalline forms of valacyclovir hydrochloride
US20050059684A1 (en) * 2002-10-16 2005-03-17 Ben-Zion Dolitzky Method for reducing residual alcohols in crystalline valacyclovir hydrochloride
AU2003277433A1 (en) * 2002-10-16 2004-05-04 Teva Pharmaceutical Industries Ltd. Method for reducing residual alcohols in crystalline valacyclovir hydrochloride
WO2004052892A1 (en) * 2002-12-09 2004-06-24 Texcontor Etablissement Anhydrous crystalline form of valacyclovir hydrochloride
EP1633753A1 (en) * 2003-05-30 2006-03-15 EOS Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ti Caret A.S. Novel crystalline forms of valacyclovir hydrochloride
KR100871621B1 (ko) * 2003-06-02 2008-12-02 테바 파마슈티컬 인더스트리즈 리미티드 발라시클로비르 히드로클로라이드의 신규한 결정질 형태
KR20060117355A (ko) * 2004-01-21 2006-11-16 테바 파마슈티컬 인더스트리즈 리미티드 발라시클로버 염산염의 제조 방법
US20060178512A1 (en) * 2005-02-04 2006-08-10 Cheruthur Govindan Method for preparing amino acid esters of nucleoside analogues
EP1746098A1 (en) * 2005-07-21 2007-01-24 SOLMAG S.p.A. Valacyclovir polymorphs and a process for the preparation thereof
US20070112193A1 (en) * 2005-11-14 2007-05-17 Khunt Mayur D Valacyclovir process
US20080281099A1 (en) * 2007-05-07 2008-11-13 Mayur Devjibhai Khunt Process for purifying valacyclovir hydrochloride and intermediates thereof

Also Published As

Publication number Publication date
MX242714B (es) 2006-12-15
CA2465928C (en) 2010-01-19
JP2005508993A (ja) 2005-04-07
KR20070020149A (ko) 2007-02-16
US20050130993A1 (en) 2005-06-16
US20030153757A1 (en) 2003-08-14
IL161969A0 (en) 2005-11-20
WO2003041647A3 (en) 2003-11-20
KR20050044449A (ko) 2005-05-12
WO2003041647A2 (en) 2003-05-22
EP1465894A4 (en) 2008-10-08
PL371732A1 (en) 2005-06-27
NO20042433L (no) 2004-07-22
HRP20040511A2 (en) 2004-10-31
CA2465928A1 (en) 2003-05-22
IN2007DE04250A (cg-RX-API-DMAC7.html) 2007-08-31
CN1307177C (zh) 2007-03-28
CN1612878A (zh) 2005-05-04
EP1465894A2 (en) 2004-10-13
MXPA04004656A (es) 2004-08-13
CA2649826A1 (en) 2003-05-22
US6849737B2 (en) 2005-02-01

Similar Documents

Publication Publication Date Title
IS7260A (is) Nýmyndun og hreinsun valasýklóvírs
NO20033387D0 (no) Modifiserte antistoffer og fremgangsmåter for anvendelse
IS7344A (is) Stýrð efnasmíði síprasídóns og samsetninga af því
NO20041975L (no) Bicyklisk oksopyridin og oksopyrimidinderivater
NO20041582L (no) Antistoffinhibitorer av GDF-8 og anvendelse derav
DE60101968D1 (de) Kristallform alpha des perindopril-tert-butylaminsalzes
DK1404809T3 (da) Forbedrede hudsubstitutter og anvendelser deraf
NO20033854D0 (no) N-but-3-enyl-norbuprenorfin og fremgangsmåter for anvendelse
NO20041449L (no) Krystallinformer av valasyklovir-hydroklorid
DK2305689T3 (da) Syntese af naturligt forekommende ecteinascidiner og relateredeforbindelser
IS7128A (is) Hreinsun á zaleploni og kristölluð form þess
NO20041968L (no) Anvendelse av cystationin
NO20021569L (no) Rensete kitiner og fremgangsmåte for deres fremstilling
IS6884A (is) Aðferðir við að nýta líffræðilegan fjölbreytileika
AR028070A1 (es) Sintesis de compuestos de ciclohexendimetanol o ciclohexandimetanol
NO20034172D0 (no) Bisykliske guanidinderivater og terapeutiske anvendelser derav
NO20042126L (no) Syntese av 2-aralkoksyadenosiner og 2-alkoksyadenosiner
PT1392670E (pt) Derivados substituidos de c-furan-2-il-metilamina e c-tiofen-2-il-metilamina
NO20033743L (no) Fremgangsmåte og fremstilling citalopram
ITBA20010029U1 (it) Gioiello di puglia
SE0004003D0 (sv) Synthesis of FLG
ITMI20010955A0 (it) Sintesi di ioduri perfluoropolieterei
DK1363896T3 (da) Syntese af beta-lapachol og mellemprodukter derfor
SE0000713D0 (sv) Methods of synthesis
UA7304S (uk) Емблема телекомпанії