IS6694A - 4-, 5-, 6- og 7-indólafleiður sem eru nytsamlegarvið meðhöndlun á MTK-truflunum - Google Patents
4-, 5-, 6- og 7-indólafleiður sem eru nytsamlegarvið meðhöndlun á MTK-truflunumInfo
- Publication number
- IS6694A IS6694A IS6694A IS6694A IS6694A IS 6694 A IS6694 A IS 6694A IS 6694 A IS6694 A IS 6694A IS 6694 A IS6694 A IS 6694A IS 6694 A IS6694 A IS 6694A
- Authority
- IS
- Iceland
- Prior art keywords
- mtk
- disorders
- treatment
- indole derivatives
- derivatives useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200001229 | 2000-08-18 | ||
| PCT/DK2001/000547 WO2002016349A1 (en) | 2000-08-18 | 2001-08-17 | 4-, 5-, 6- and 7-indole derivatives useful for the treatment of cns disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS6694A true IS6694A (is) | 2003-01-20 |
Family
ID=8159658
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS6694A IS6694A (is) | 2000-08-18 | 2003-01-20 | 4-, 5-, 6- og 7-indólafleiður sem eru nytsamlegarvið meðhöndlun á MTK-truflunum |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US6958338B2 (is) |
| EP (1) | EP1309586B1 (is) |
| JP (1) | JP2004506731A (is) |
| KR (1) | KR20030022363A (is) |
| CN (1) | CN1243750C (is) |
| AR (1) | AR030357A1 (is) |
| AT (1) | ATE321040T1 (is) |
| AU (2) | AU7961101A (is) |
| BG (1) | BG107611A (is) |
| BR (1) | BR0113452A (is) |
| CA (1) | CA2419266A1 (is) |
| CZ (1) | CZ2003461A3 (is) |
| DE (1) | DE60118205T2 (is) |
| DK (1) | DK1309586T3 (is) |
| EA (1) | EA006155B1 (is) |
| ES (1) | ES2257424T3 (is) |
| HK (1) | HK1059438A1 (is) |
| HR (1) | HRP20030052A2 (is) |
| HU (1) | HUP0302777A2 (is) |
| IL (1) | IL154051A0 (is) |
| IS (1) | IS6694A (is) |
| MX (1) | MXPA03000838A (is) |
| NO (1) | NO20030522L (is) |
| NZ (1) | NZ523786A (is) |
| PL (1) | PL363309A1 (is) |
| PT (1) | PT1309586E (is) |
| SK (1) | SK3212003A3 (is) |
| UA (1) | UA74837C2 (is) |
| WO (1) | WO2002016349A1 (is) |
| ZA (1) | ZA200300562B (is) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2520567A3 (en) * | 2006-02-23 | 2012-12-12 | Shionogi & Co., Ltd. | Nitrogen-containing heterocycle derivatives substituted with cyclic group |
| US7645789B2 (en) | 2006-04-07 | 2010-01-12 | Vertex Pharmaceuticals Incorporated | Indole derivatives as CFTR modulators |
| SI2674428T1 (sl) | 2006-04-07 | 2016-07-29 | Vertex Pharmaceuticals Incorporated | Modulatorji transporterjev atp-vezavne kasete |
| US10022352B2 (en) | 2006-04-07 | 2018-07-17 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
| US8563573B2 (en) | 2007-11-02 | 2013-10-22 | Vertex Pharmaceuticals Incorporated | Azaindole derivatives as CFTR modulators |
| TWI404702B (zh) * | 2007-08-31 | 2013-08-11 | Lundbeck & Co As H | 兒茶酚胺衍生物和其前藥 |
| US8802868B2 (en) | 2010-03-25 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide |
| EP3045452A1 (en) | 2010-04-22 | 2016-07-20 | Vertex Pharmaceuticals Inc. | Process of producing cycloalkylcarboxamido-indole compounds |
| US9012496B2 (en) | 2012-07-16 | 2015-04-21 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions of (R)-1-(2,2-difluorobenzo[D][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide and administration thereof |
| JO3425B1 (ar) | 2013-07-15 | 2019-10-20 | Novartis Ag | مشتقات البابيريدينيل-اندول واستخدامها كعامل متمم لمثبطات b |
| HUE062736T2 (hu) | 2014-04-15 | 2023-12-28 | Vertex Pharma | Gyógyszerészeti készítmények cisztás fibrózis transzmembrán konduktancia regulátor által mediált betegségek kezelésére |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3421641A1 (de) * | 1984-06-09 | 1985-12-12 | Merck Patent Gmbh, 6100 Darmstadt | Indolderivate |
| MX173362B (es) * | 1987-03-02 | 1994-02-23 | Pfizer | Compuestos de piperazinil heterociclicos y procedimiento para su preparacion |
| US4831031A (en) * | 1988-01-22 | 1989-05-16 | Pfizer Inc. | Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity |
| WO1994021627A1 (en) * | 1993-03-18 | 1994-09-29 | Merck Sharp & Dohme Limited | Indole derivatives as dopamine d4 antagonists |
| JPH09512542A (ja) * | 1994-04-28 | 1997-12-16 | メルク シヤープ エンド ドーム リミテツド | Ｄ▲下４▼リセプタ拮抗剤としてのベンゾフラン誘導体 |
| DE19500689A1 (de) * | 1995-01-12 | 1996-07-18 | Merck Patent Gmbh | Indolpiperidin-Derivate |
| GB9520731D0 (en) * | 1995-10-10 | 1995-12-13 | Merck Sharp & Dohme | Therapeutic agents |
| GB9604036D0 (en) * | 1996-02-26 | 1996-04-24 | Merck Sharp & Dohme | Therapeutic agents |
| ATE346050T1 (de) * | 1998-01-27 | 2006-12-15 | Aventis Pharma Inc | Substituierte oxoazaheterocyclyl faktor xa hemmer |
| ATE286045T1 (de) * | 1999-10-19 | 2005-01-15 | Merck & Co Inc | Tyrosin kinaseinhibitoren |
| US6727264B1 (en) * | 2001-07-05 | 2004-04-27 | Synaptic Pharmaceutical Corporation | Substituted anilinic piperidines as MCH selective antagonists |
-
2001
- 2001-08-15 AR ARP010103899A patent/AR030357A1/es not_active Application Discontinuation
- 2001-08-17 NZ NZ523786A patent/NZ523786A/en unknown
- 2001-08-17 UA UA2003010504A patent/UA74837C2/uk unknown
- 2001-08-17 EP EP01957788A patent/EP1309586B1/en not_active Expired - Lifetime
- 2001-08-17 EA EA200300278A patent/EA006155B1/ru not_active IP Right Cessation
- 2001-08-17 HU HU0302777A patent/HUP0302777A2/hu unknown
- 2001-08-17 MX MXPA03000838A patent/MXPA03000838A/es active IP Right Grant
- 2001-08-17 AU AU7961101A patent/AU7961101A/xx active Pending
- 2001-08-17 CA CA002419266A patent/CA2419266A1/en not_active Abandoned
- 2001-08-17 CN CNB018142400A patent/CN1243750C/zh not_active Expired - Fee Related
- 2001-08-17 SK SK321-2003A patent/SK3212003A3/sk unknown
- 2001-08-17 WO PCT/DK2001/000547 patent/WO2002016349A1/en active IP Right Grant
- 2001-08-17 DE DE60118205T patent/DE60118205T2/de not_active Expired - Fee Related
- 2001-08-17 PL PL01363309A patent/PL363309A1/xx not_active Application Discontinuation
- 2001-08-17 BR BR0113452-3A patent/BR0113452A/pt not_active IP Right Cessation
- 2001-08-17 CZ CZ2003461A patent/CZ2003461A3/cs unknown
- 2001-08-17 DK DK01957788T patent/DK1309586T3/da active
- 2001-08-17 AT AT01957788T patent/ATE321040T1/de not_active IP Right Cessation
- 2001-08-17 JP JP2002521450A patent/JP2004506731A/ja not_active Withdrawn
- 2001-08-17 IL IL15405101A patent/IL154051A0/xx unknown
- 2001-08-17 AU AU2001279611A patent/AU2001279611B2/en not_active Ceased
- 2001-08-17 ES ES01957788T patent/ES2257424T3/es not_active Expired - Lifetime
- 2001-08-17 KR KR10-2003-7001687A patent/KR20030022363A/ko not_active Application Discontinuation
- 2001-08-17 PT PT01957788T patent/PT1309586E/pt unknown
-
2003
- 2003-01-20 IS IS6694A patent/IS6694A/is unknown
- 2003-01-21 ZA ZA200300562A patent/ZA200300562B/en unknown
- 2003-01-27 HR HR20030052A patent/HRP20030052A2/xx not_active Application Discontinuation
- 2003-02-03 NO NO20030522A patent/NO20030522L/no not_active Application Discontinuation
- 2003-02-04 US US10/359,052 patent/US6958338B2/en not_active Expired - Fee Related
- 2003-03-06 BG BG107611A patent/BG107611A/bg unknown
-
2004
- 2004-03-31 HK HK04102360A patent/HK1059438A1/xx not_active IP Right Cessation
-
2005
- 2005-09-01 US US11/219,544 patent/US7105543B2/en not_active Expired - Fee Related
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