IN2015DN03962A - - Google Patents

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Publication number
IN2015DN03962A
IN2015DN03962A IN3962DEN2015A IN2015DN03962A IN 2015DN03962 A IN2015DN03962 A IN 2015DN03962A IN 3962DEN2015 A IN3962DEN2015 A IN 3962DEN2015A IN 2015DN03962 A IN2015DN03962 A IN 2015DN03962A
Authority
IN
India
Prior art keywords
mycobacterium
proteins
esx
secreted
tuberculosis
Prior art date
Application number
Other languages
English (en)
Inventor
Claus Aagaard
Ida Rosenkrands
Truc Thi Kim Thanh Hoang
Peter Andersen
Original Assignee
Statens Seruminstitut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Statens Seruminstitut filed Critical Statens Seruminstitut
Publication of IN2015DN03962A publication Critical patent/IN2015DN03962A/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
IN3962DEN2015 2012-10-23 2013-10-18 IN2015DN03962A (xx)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA201200652 2012-10-23
DKPA201200654 2012-10-23
DKPA201200653 2012-10-23
DKPA201300477 2013-08-23
PCT/DK2013/000070 WO2014063704A2 (en) 2012-10-23 2013-10-18 M. tuberculosis vaccines

Publications (1)

Publication Number Publication Date
IN2015DN03962A true IN2015DN03962A (xx) 2015-10-02

Family

ID=49679267

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3962DEN2015 IN2015DN03962A (xx) 2012-10-23 2013-10-18

Country Status (8)

Country Link
US (1) US9526773B2 (xx)
EP (1) EP2912056B1 (xx)
JP (1) JP6470179B2 (xx)
CN (1) CN104736555B (xx)
BR (1) BR112015009070A2 (xx)
IN (1) IN2015DN03962A (xx)
WO (1) WO2014063704A2 (xx)
ZA (1) ZA201503467B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3092000A1 (en) * 2014-01-09 2016-11-16 Transgene SA Fusion of heterooligomeric mycobacterial antigens
WO2015161853A1 (en) * 2014-04-24 2015-10-29 Statens Serum Institut New m.tuberculosis vaccines
AU2016333474A1 (en) 2015-09-30 2018-03-22 Boehringer Ingelheim Vetmedica Gmbh Improved modular antigen transportation molecules and uses therof in animals
CN105218681B (zh) * 2015-10-21 2019-06-25 中山大学 一种用于诱导外周血单个核细胞产生结核特异性细胞因子的融合蛋白
CN105218680B (zh) * 2015-10-21 2019-06-25 中山大学 一种用于诱导外周血单个核细胞产生细胞因子的结核分支杆菌融合蛋白
CN105567660B (zh) * 2016-01-08 2018-11-20 中国人民解放军第四军医大学 一种大肠杆菌重组表达结核分枝杆菌Rv2837c活性蛋白的方法及其应用
KR20190009308A (ko) * 2016-05-21 2019-01-28 인펙셔스 디지즈 리서치 인스티튜트 (아이디알아이) 2차 결핵 및 비결핵성 마이코박테리아 감염을 치료하기 위한 조성물 및 방법
US11091775B2 (en) 2016-06-22 2021-08-17 Oregon Health And Science University Recombinant cytomegalovirus vectors as vaccines for tuberculosis
EP3555630B1 (en) 2016-12-14 2023-05-31 Becton, Dickinson and Company Methods and compositions for obtaining a tuberculosis assessment in a subject
WO2018127608A1 (en) * 2017-01-09 2018-07-12 Biomunex Pharmaceuticals A polypeptide linker for preparing multispecific antibodies
US11638749B2 (en) 2017-10-17 2023-05-02 International Aids Vaccine Initiative, Inc. Tuberculosis antigen cassettes
KR20220032054A (ko) 2019-06-14 2022-03-15 스태튼스 세룸 인스티튜트 결핵 백신용 융합 단백질
WO2021022001A1 (en) * 2019-08-01 2021-02-04 Trustees Of Tufts College Vaccine compositions and methods of selecting antigens
CN110590958B (zh) * 2019-09-11 2021-04-13 中国人民解放军总医院第八医学中心 一种串联多肽及其在抗结核分枝杆菌的免疫保护中的应用
WO2023156676A1 (en) 2022-02-21 2023-08-24 Statens Serum Institut A novel cationic adjuvant composition
CN115184603B (zh) * 2022-06-30 2024-02-06 首都医科大学附属北京胸科医院 EspC蛋白在制备结核分枝杆菌分离或富集产品中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100797876B1 (ko) * 1998-04-07 2008-01-24 코릭사 코포레이션 마이코박테리움 튜베르쿨로시스 항원의 융합 단백질 및이의 용도
EP1350839B1 (en) * 2002-04-05 2010-06-02 Institut Pasteur Identification of virulence associated regions RD1 and RD5 enabling the development of improved vaccines of M. bovis BCG and M. microti
TR201903223T4 (tr) * 2009-04-24 2019-03-21 Statens Seruminstitut Reaktivasyonu önlemek üzere bir tüberküloz TB aşısı.
WO2012057904A1 (en) 2010-10-27 2012-05-03 Infectious Disease Research Institute Mycobacterium tuberculosis antigens and combinations thereof having high seroreactivity

Also Published As

Publication number Publication date
US9526773B2 (en) 2016-12-27
US20150290311A1 (en) 2015-10-15
ZA201503467B (en) 2016-11-30
WO2014063704A3 (en) 2014-06-19
JP2015536309A (ja) 2015-12-21
CN104736555A (zh) 2015-06-24
CN104736555B (zh) 2019-06-21
EP2912056A2 (en) 2015-09-02
BR112015009070A2 (pt) 2017-07-04
EP2912056B1 (en) 2020-02-12
JP6470179B2 (ja) 2019-02-13
WO2014063704A2 (en) 2014-05-01
WO2014063704A8 (en) 2015-07-30

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