IN2015DN03962A - - Google Patents
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- Publication number
- IN2015DN03962A IN2015DN03962A IN3962DEN2015A IN2015DN03962A IN 2015DN03962 A IN2015DN03962 A IN 2015DN03962A IN 3962DEN2015 A IN3962DEN2015 A IN 3962DEN2015A IN 2015DN03962 A IN2015DN03962 A IN 2015DN03962A
- Authority
- IN
- India
- Prior art keywords
- mycobacterium
- proteins
- esx
- secreted
- tuberculosis
- Prior art date
Links
- 239000000427 antigen Substances 0.000 abstract 3
- 102000036639 antigens Human genes 0.000 abstract 3
- 108091007433 antigens Proteins 0.000 abstract 3
- 102000037865 fusion proteins Human genes 0.000 abstract 2
- 108020001507 fusion proteins Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- IMCUVBSHZXQITN-UHFFFAOYSA-N 4-[[4-(4-chlorophenyl)-5-(2-methoxy-2-oxoethyl)-1,3-thiazol-2-yl]amino]-4-oxobutanoic acid Chemical compound S1C(NC(=O)CCC(O)=O)=NC(C=2C=CC(Cl)=CC=2)=C1CC(=O)OC IMCUVBSHZXQITN-UHFFFAOYSA-N 0.000 abstract 1
- 241001467553 Mycobacterium africanum Species 0.000 abstract 1
- 241000186366 Mycobacterium bovis Species 0.000 abstract 1
- 241001312372 Mycobacterium canettii Species 0.000 abstract 1
- 241000187919 Mycobacterium microti Species 0.000 abstract 1
- 241000699502 Mycobacterium mungi Species 0.000 abstract 1
- 241001457456 Mycobacterium pinnipedii Species 0.000 abstract 1
- 241000187479 Mycobacterium tuberculosis Species 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 201000008827 tuberculosis Diseases 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA201200652 | 2012-10-23 | ||
| DKPA201200654 | 2012-10-23 | ||
| DKPA201200653 | 2012-10-23 | ||
| DKPA201300477 | 2013-08-23 | ||
| PCT/DK2013/000070 WO2014063704A2 (en) | 2012-10-23 | 2013-10-18 | M. tuberculosis vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2015DN03962A true IN2015DN03962A (https=) | 2015-10-02 |
Family
ID=49679267
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN3962DEN2015 IN2015DN03962A (https=) | 2012-10-23 | 2013-10-18 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9526773B2 (https=) |
| EP (1) | EP2912056B1 (https=) |
| JP (1) | JP6470179B2 (https=) |
| CN (1) | CN104736555B (https=) |
| BR (1) | BR112015009070A2 (https=) |
| IN (1) | IN2015DN03962A (https=) |
| WO (1) | WO2014063704A2 (https=) |
| ZA (1) | ZA201503467B (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015104380A1 (en) * | 2014-01-09 | 2015-07-16 | Transgene Sa | Fusion of heterooligomeric mycobacterial antigens |
| US10004793B2 (en) | 2014-04-24 | 2018-06-26 | Statens Serum Institut | M.tuberculosis vaccines |
| JP2018527395A (ja) * | 2015-09-30 | 2018-09-20 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーＢｏｅｈｒｉｎｇｅｒ Ｉｎｇｅｌｈｅｉｍ Ｖｅｔｍｅｄｉｃａ ＧｍｂＨ | 改良モジュール型抗原移送分子及び動物におけるその使用 |
| CN105218681B (zh) * | 2015-10-21 | 2019-06-25 | 中山大学 | 一种用于诱导外周血单个核细胞产生结核特异性细胞因子的融合蛋白 |
| CN105218680B (zh) * | 2015-10-21 | 2019-06-25 | 中山大学 | 一种用于诱导外周血单个核细胞产生细胞因子的结核分支杆菌融合蛋白 |
| CN105567660B (zh) * | 2016-01-08 | 2018-11-20 | 中国人民解放军第四军医大学 | 一种大肠杆菌重组表达结核分枝杆菌Rv2837c活性蛋白的方法及其应用 |
| JP2019521095A (ja) * | 2016-05-21 | 2019-07-25 | インフェクシャス ディズィーズ リサーチ インスティチュート | 二次性結核および非結核性マイコバクテリウム感染症を治療するための組成物および方法 |
| CN109843321A (zh) | 2016-06-22 | 2019-06-04 | 国际艾滋病疫苗行动组织公司 | 作为结核病疫苗的重组巨细胞病毒载体 |
| US10684275B2 (en) | 2016-12-14 | 2020-06-16 | Becton, Dickinson And Company | Methods and compositions for obtaining a tuberculosis assessment in a subject |
| KR102589422B1 (ko) * | 2017-01-09 | 2023-10-13 | 바이오뮤넥스 파마슈티컬스 | 다중특이적 항체를 제조하기 위한 폴리펩티드 링커 |
| WO2019079155A1 (en) | 2017-10-17 | 2019-04-25 | International Aids Vaccine Initiative, Inc. | CASSETTES OF ANTIGENS OF TUBERCULOSIS |
| EP3983011A1 (en) | 2019-06-14 | 2022-04-20 | Statens Serum Institut | Fusion proteins for tuberculosis vaccines |
| US12599655B2 (en) | 2019-08-01 | 2026-04-14 | Trustees Of Tufts College | Neisseria gonorrhoeae vaccine compositions and methods of selecting antigens |
| CN110590958B (zh) * | 2019-09-11 | 2021-04-13 | 中国人民解放军总医院第八医学中心 | 一种串联多肽及其在抗结核分枝杆菌的免疫保护中的应用 |
| CN118765203A (zh) | 2022-02-21 | 2024-10-11 | 史坦恩斯血清研究所 | 一种新型阳离子佐剂组合物 |
| CN115300618B (zh) * | 2022-05-11 | 2026-03-27 | 中国农业大学 | 基于牛β防御素5的结核疫苗及其在预防结核病中的应用 |
| CN115184603B (zh) * | 2022-06-30 | 2024-02-06 | 首都医科大学附属北京胸科医院 | EspC蛋白在制备结核分枝杆菌分离或富集产品中的应用 |
| KR20250087737A (ko) * | 2023-12-06 | 2025-06-17 | 주식회사 미코라파 | 결핵균에 대한 살균면역을 유도하는 융합단백질을 포함하는 결핵 백신 조성물 |
| CN118108815B (zh) * | 2024-04-23 | 2024-07-23 | 成都康华生物制品股份有限公司 | 结核分枝杆菌多免疫原抗原、编码其的mRNA、应用 |
| US20250387462A1 (en) * | 2024-06-21 | 2025-12-25 | Akagera Medicines, Inc. | Lipid nanoparticles for delivery of nucleic acids and vaccine for the prevention of tuberculosis or other mycobacterial infections |
| CN119823286B (zh) * | 2025-01-16 | 2026-02-06 | 中国动物卫生与流行病学中心 | 一种重组蛋白抗原及其在制备用于检测牛伽马干扰素试剂盒中的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL202844B1 (pl) * | 1998-04-07 | 2009-07-31 | Corixa Corp | Immunogeniczny polipeptyd, polinukleotyd, polipeptyd, kompozycja farmaceutyczna, wektor ekspresji, kompozycja szczepionki, polipeptyd do stosowania w leczeniu lub zapobieganiu infekcjom Mycobacterium tuberculosis, polinukleotyd do stosowania w leczeniu lub zapobieganiu infekcjom Mycobacterium tuberculosis i sposób wytwarzania polipeptydu |
| ATE535600T1 (de) * | 2002-04-05 | 2011-12-15 | Pasteur Institut | Identifizierung der virulenz-assoziierten region rd1, die die entwicklung von verbesserten impstoffen mit m. microti ermöglicht |
| MX2011011186A (es) * | 2009-04-24 | 2012-02-13 | Una vacuna antituberculosis tb para evitar la reactivacion. | |
| US20130345079A1 (en) * | 2010-10-27 | 2013-12-26 | Infectious Disease Research Institute | Mycobacterium tuberculosis antigens and combinations thereof having high seroreactivity |
-
2013
- 2013-10-18 JP JP2015537146A patent/JP6470179B2/ja not_active Expired - Fee Related
- 2013-10-18 EP EP13798236.9A patent/EP2912056B1/en active Active
- 2013-10-18 IN IN3962DEN2015 patent/IN2015DN03962A/en unknown
- 2013-10-18 WO PCT/DK2013/000070 patent/WO2014063704A2/en not_active Ceased
- 2013-10-18 CN CN201380054841.4A patent/CN104736555B/zh not_active Expired - Fee Related
- 2013-10-18 BR BR112015009070A patent/BR112015009070A2/pt not_active IP Right Cessation
- 2013-10-18 US US14/437,998 patent/US9526773B2/en not_active Expired - Fee Related
-
2015
- 2015-05-18 ZA ZA2015/03467A patent/ZA201503467B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN104736555A (zh) | 2015-06-24 |
| EP2912056B1 (en) | 2020-02-12 |
| ZA201503467B (en) | 2016-11-30 |
| CN104736555B (zh) | 2019-06-21 |
| US9526773B2 (en) | 2016-12-27 |
| WO2014063704A3 (en) | 2014-06-19 |
| JP2015536309A (ja) | 2015-12-21 |
| US20150290311A1 (en) | 2015-10-15 |
| JP6470179B2 (ja) | 2019-02-13 |
| EP2912056A2 (en) | 2015-09-02 |
| WO2014063704A2 (en) | 2014-05-01 |
| WO2014063704A8 (en) | 2015-07-30 |
| BR112015009070A2 (pt) | 2017-07-04 |
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