IN2015DN03854A - - Google Patents

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Publication number
IN2015DN03854A
IN2015DN03854A IN3854DEN2015A IN2015DN03854A IN 2015DN03854 A IN2015DN03854 A IN 2015DN03854A IN 3854DEN2015 A IN3854DEN2015 A IN 3854DEN2015A IN 2015DN03854 A IN2015DN03854 A IN 2015DN03854A
Authority
IN
India
Prior art keywords
methods
formula
administering
relates
present
Prior art date
Application number
Other languages
English (en)
Inventor
James Wallace Sleigh
William Alexander Denny
Jiney Jose
Swarnalatha Akuratiya Gamage
Martyn Gregory Harvey
Logan James Voss
Original Assignee
Auckland Uniservices Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Auckland Uniservices Ltd filed Critical Auckland Uniservices Ltd
Publication of IN2015DN03854A publication Critical patent/IN2015DN03854A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/14Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of carbon skeletons containing rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/20Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
IN3854DEN2015 2012-10-08 2013-10-08 IN2015DN03854A (forum.php)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NZ60288512 2012-10-08
NZ61120213 2013-05-28
PCT/IB2013/059191 WO2014057414A1 (en) 2012-10-08 2013-10-08 Ketamine derivatives

Publications (1)

Publication Number Publication Date
IN2015DN03854A true IN2015DN03854A (forum.php) 2015-10-02

Family

ID=50476991

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3854DEN2015 IN2015DN03854A (forum.php) 2012-10-08 2013-10-08

Country Status (13)

Country Link
US (3) US20150259277A1 (forum.php)
EP (1) EP2903963A4 (forum.php)
JP (2) JP6309957B2 (forum.php)
KR (1) KR20150065873A (forum.php)
CN (1) CN104837810B (forum.php)
AU (1) AU2013328280B2 (forum.php)
BR (1) BR112015007647A2 (forum.php)
CA (1) CA2922340A1 (forum.php)
EA (1) EA201590697A1 (forum.php)
HK (1) HK1212673A1 (forum.php)
IN (1) IN2015DN03854A (forum.php)
MX (1) MX2015004362A (forum.php)
WO (1) WO2014057414A1 (forum.php)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20150065873A (ko) * 2012-10-08 2015-06-15 오클랜드 유니서비시즈 리미티드 케타민 유도체
US20160332962A1 (en) * 2015-05-13 2016-11-17 Janssen Pharmaceutica Nv (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
EP3297620A4 (en) 2015-06-27 2019-01-09 Shenox Pharmaceuticals, LLC TRANSDERMAL DELIVERY SYSTEM FOR KETAMINE
US11827606B2 (en) 2015-11-18 2023-11-28 Spirify Pharma Inc. Phenyl cyclohexanone derivatives and methods of making and using them
US11111210B2 (en) 2015-11-18 2021-09-07 Spirify Pharma Inc. Phenyl cyclohexanone derivatives and methods of making and using them
CN115108927A (zh) * 2016-03-25 2022-09-27 美国政府健康及人类服务部 (2r,6r)-羟基去甲氯胺酮和(2s,6s)-羟基去甲氯胺酮的晶型和合成方法
CN114805139B (zh) * 2018-01-10 2023-10-20 凯瑞康宁生物工程(武汉)有限公司 氯胺酮的前药、其组合物和用途
WO2019186357A1 (en) * 2018-03-26 2019-10-03 Cellix Bio Private Limited Compositions and methods for the treatment of neurological diseases
ES2960813T3 (es) * 2018-06-04 2024-03-06 Us Health Proceso para la síntesis y purificación de (2r,6r)-hidroxinorketamina
CN112125816A (zh) * 2020-03-17 2020-12-25 国药集团工业有限公司 一种氯胺酮、其衍生物或其盐的消旋化方法
WO2023018966A1 (en) 2021-08-13 2023-02-16 XWPharma Ltd. Pharmaceutical compositions and oral dosage forms of ketamine derivatives
CN115677444A (zh) * 2022-10-26 2023-02-03 公安部第三研究所 同位素毒品代谢物标记化合物及其制备方法、用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3254124A (en) * 1962-06-29 1966-05-31 Parke Davis & Co Aminoketones and methods for their production
GB1134146A (en) * 1967-09-15 1968-11-20 Parke Davis & Co New organic amines and methods for their production
US5019583A (en) 1989-02-15 1991-05-28 Glaxo Inc. N-phenyl-N-(4-piperidinyl)amides useful as analgesics
US5466700A (en) 1993-08-30 1995-11-14 Glaxo Wellcome Inc. Anesthetic use of N-phenyl-N-(4-piperidinyl)amides
US5866591A (en) 1996-09-11 1999-02-02 Glaxo Wellcome Inc. Stable formulations of remifentanil
CN1441790A (zh) * 2000-01-28 2003-09-10 罗姆和哈斯公司 增强性质的药物
US20040248963A1 (en) 2001-11-23 2004-12-09 Bueno Melendo Ana Belen Prodrugs of excitatory amino acids
EP1333023B1 (en) * 2002-01-31 2010-12-22 Randox Laboratories Ltd. Immunogens, antibodies and conjugates to ketamine and its metabolites
JP2006510618A (ja) * 2002-11-18 2006-03-30 ヤウポン セラピューティクス,インコーポレーテッド ノルケタミンおよびケタミン/ノルケタミンプロドラッグの鎮痛的使用
CU20080044A7 (es) * 2005-09-28 2011-04-26 Composiciones farmacéuticas para el tratamiento de trastornos del oído interno.
CN101765582A (zh) * 2007-04-26 2010-06-30 奥斯拜客斯制药有限公司 氘标记的氯胺酮
CN109793725B (zh) 2011-10-14 2023-07-25 美国政府健康及人类服务部 治疗忧郁症和神经性疼痛的药物组合物及其应用
KR20150065873A (ko) * 2012-10-08 2015-06-15 오클랜드 유니서비시즈 리미티드 케타민 유도체

Also Published As

Publication number Publication date
EP2903963A1 (en) 2015-08-12
EP2903963A4 (en) 2016-05-25
AU2013328280A1 (en) 2015-05-14
AU2013328280B2 (en) 2017-12-21
WO2014057414A9 (en) 2014-12-18
US20150259277A1 (en) 2015-09-17
US20190169113A1 (en) 2019-06-06
US20170190653A1 (en) 2017-07-06
BR112015007647A2 (pt) 2017-07-04
CN104837810A (zh) 2015-08-12
US10239825B2 (en) 2019-03-26
JP6309957B2 (ja) 2018-04-11
JP2018127466A (ja) 2018-08-16
WO2014057414A1 (en) 2014-04-17
KR20150065873A (ko) 2015-06-15
JP2015535847A (ja) 2015-12-17
HK1212673A1 (zh) 2016-06-17
MX2015004362A (es) 2015-12-08
EA201590697A1 (ru) 2015-09-30
CN104837810B (zh) 2019-08-06
CA2922340A1 (en) 2014-04-17

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