IN2014MU00740A - - Google Patents
Info
- Publication number
- IN2014MU00740A IN2014MU00740A IN740MU2014A IN2014MU00740A IN 2014MU00740 A IN2014MU00740 A IN 2014MU00740A IN 740MU2014 A IN740MU2014 A IN 740MU2014A IN 2014MU00740 A IN2014MU00740 A IN 2014MU00740A
- Authority
- IN
- India
- Prior art keywords
- romidepsin
- purification steps
- crystals
- terms
- preparation
- Prior art date
Links
- 238000000034 method Methods 0.000 abstract 8
- OHRURASPPZQGQM-GCCNXGTGSA-N romidepsin Chemical compound O1C(=O)[C@H](C(C)C)NC(=O)C(=C/C)/NC(=O)[C@H]2CSSCC\C=C\[C@@H]1CC(=O)N[C@H](C(C)C)C(=O)N2 OHRURASPPZQGQM-GCCNXGTGSA-N 0.000 abstract 5
- 229960003452 romidepsin Drugs 0.000 abstract 5
- OHRURASPPZQGQM-UHFFFAOYSA-N romidepsin Natural products O1C(=O)C(C(C)C)NC(=O)C(=CC)NC(=O)C2CSSCCC=CC1CC(=O)NC(C(C)C)C(=O)N2 OHRURASPPZQGQM-UHFFFAOYSA-N 0.000 abstract 5
- 108010091666 romidepsin Proteins 0.000 abstract 5
- 238000011097 chromatography purification Methods 0.000 abstract 2
- 239000013078 crystal Substances 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 238000000746 purification Methods 0.000 abstract 2
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 238000004128 high performance liquid chromatography Methods 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/123,295 US10294276B2 (en) | 2014-03-04 | 2015-03-02 | Process for isolation of romidepsin from fermentation broth and preparation of crystals of romidepsin |
| IN740MU2014 IN2014MU00740A (ko) | 2014-03-04 | 2015-03-02 | |
| PCT/IN2015/000113 WO2015136548A2 (en) | 2014-03-04 | 2015-03-02 | A process for isolation of romidepsin from fermentation broth and preparation of crystals of romidepsin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN740MU2014 IN2014MU00740A (ko) | 2014-03-04 | 2015-03-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014MU00740A true IN2014MU00740A (ko) | 2015-09-25 |
Family
ID=54072543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN740MU2014 IN2014MU00740A (ko) | 2014-03-04 | 2015-03-02 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US10294276B2 (ko) |
| IN (1) | IN2014MU00740A (ko) |
| WO (1) | WO2015136548A2 (ko) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8817743D0 (en) * | 1988-07-26 | 1988-09-01 | Fujisawa Pharmaceutical Co | Fr901228 substance & preparation thereof |
| JP2004508049A (ja) * | 2000-09-01 | 2004-03-18 | 藤沢薬品工業株式会社 | Ｆｒ９０１２２８物質の製造法 |
-
2015
- 2015-03-02 WO PCT/IN2015/000113 patent/WO2015136548A2/en active Application Filing
- 2015-03-02 IN IN740MU2014 patent/IN2014MU00740A/en unknown
- 2015-03-02 US US15/123,295 patent/US10294276B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US10294276B2 (en) | 2019-05-21 |
| WO2015136548A3 (en) | 2016-01-28 |
| WO2015136548A4 (en) | 2016-03-31 |
| WO2015136548A2 (en) | 2015-09-17 |
| US20170073374A1 (en) | 2017-03-16 |
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