IN2014MN02127A - - Google Patents

Info

Publication number
IN2014MN02127A
IN2014MN02127A IN2127MUN2014A IN2014MN02127A IN 2014MN02127 A IN2014MN02127 A IN 2014MN02127A IN 2127MUN2014 A IN2127MUN2014 A IN 2127MUN2014A IN 2014MN02127 A IN2014MN02127 A IN 2014MN02127A
Authority
IN
India
Prior art keywords
compounds
calcium
crac
channel
formula
Prior art date
Application number
Other languages
English (en)
Inventor
Nageswara Rao Irlapati
Gokul Keruji Deshmukh
Nilesh Raghunath Khedkar
Kiran Chandrashekhar Kulkarni
Zubair Abdul Wajid Shaikh
Neelima Sinha
Venkata P Palle
Rajender Kumar Kamboj
Original Assignee
Lupin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lupin Ltd filed Critical Lupin Ltd
Priority to IN2127MUN2014 priority Critical patent/IN2014MN02127A/en
Publication of IN2014MN02127A publication Critical patent/IN2014MN02127A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IN2127MUN2014 2012-05-02 2013-05-01 IN2014MN02127A (en:Method)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IN2127MUN2014 IN2014MN02127A (en:Method) 2012-05-02 2013-05-01

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN6KO2012 2012-05-02
IN1474KO2012 2012-12-28
IN2127MUN2014 IN2014MN02127A (en:Method) 2012-05-02 2013-05-01
PCT/IB2013/053446 WO2013164773A1 (en) 2012-05-02 2013-05-01 Substituted pyrazole compounds as crac modulators

Publications (1)

Publication Number Publication Date
IN2014MN02127A true IN2014MN02127A (en:Method) 2015-09-11

Family

ID=48428566

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2127MUN2014 IN2014MN02127A (en:Method) 2012-05-02 2013-05-01

Country Status (7)

Country Link
US (2) US9409898B2 (en:Method)
EP (1) EP2844656A1 (en:Method)
AU (1) AU2013255441B2 (en:Method)
CA (1) CA2871222A1 (en:Method)
IN (1) IN2014MN02127A (en:Method)
WO (1) WO2013164773A1 (en:Method)
ZA (1) ZA201407668B (en:Method)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015197187A1 (en) * 2014-06-24 2015-12-30 Grünenthal GmbH Pyrazolyl-based carboxamides v
WO2015197188A1 (en) * 2014-06-24 2015-12-30 Grünenthal GmbH Pyrazolyl-based carboxamides as crac inhibitors
WO2016187182A1 (en) 2015-05-18 2016-11-24 Beth Israel Deaconess Medical Center, Inc. Substance p, mast cell degranulation inhibitors, and peripheral neuropathy
US20220040162A1 (en) 2018-09-14 2022-02-10 Rhizen Pharmaceuticals Ag Compositions comprising a crac inhibitor and a corticosteroid and methods of use thereof
US11034669B2 (en) 2018-11-30 2021-06-15 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
CN113993847A (zh) 2019-06-06 2022-01-28 巴斯夫欧洲公司 杀真菌的n-(吡啶-3-基)羧酰胺类
CN110604735B (zh) * 2019-09-18 2022-10-25 华东师范大学 一种治疗肝纤维化、硬皮病的化合物及其应用
WO2021063735A1 (en) 2019-10-02 2021-04-08 Basf Se New bicyclic pyridine derivatives

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU751139B2 (en) 1997-10-13 2002-08-08 Astellas Pharma Inc. Amide derivative
WO1999051580A1 (en) * 1998-04-08 1999-10-14 Abbott Laboratories Pyrazole inhibitors of cytokine production
AU4229999A (en) 1998-06-05 1999-12-20 Boehringer Ingelheim Pharmaceuticals, Inc. Substituted 1-(4-aminophenyl)pyrazoles and their use as anti-inflammatory agents
US20050107436A1 (en) 2003-07-23 2005-05-19 Synta Pharmaceuticals Corp. Compounds for inflammation and immune-related uses
CN101083985A (zh) 2004-09-21 2007-12-05 幸讬制药公司 用于炎症及免疫相关用途的化合物
JP5184891B2 (ja) 2005-01-07 2013-04-17 シンタ ファーマシューティカルズ コーポレーション 炎症及び免疫に関連する用途に用いる化合物
WO2006081389A1 (en) 2005-01-25 2006-08-03 Synta Pharmaceuticals Corp. Thiophene compounds for inflammation and immune-related uses
US8518950B2 (en) 2005-01-25 2013-08-27 Synta Pharmaceuticals Corp. 2-amido pyrazines for inflammation and immune related uses
CA2640090A1 (en) 2006-01-25 2007-08-02 Synta Pharmaceuticals Corp. Substituted aromatic compounds for inflammation and immune-related uses
US8623871B2 (en) 2006-01-25 2014-01-07 Synta Pharmaceuticals Corp. Substituted biaryl compounds for inflammation and immune-related uses
TWI417096B (zh) 2006-01-25 2013-12-01 Synta Pharmaceuticals Corp 用於發炎及免疫相關用途之苯基及吡啶基化合物
ES2403368T3 (es) 2006-01-31 2013-05-17 Synta Pharmaceuticals Corporation Compuestos de piridilfenilo para la inflamación y usos inmunorrelacionados
EP2182808A4 (en) 2007-08-01 2011-09-21 Synta Pharmaceuticals Corp Pyridine compounds for inflammatory and immune uses
AU2008299220B2 (en) 2007-09-10 2011-07-21 Calcimedica, Inc. Compounds that modulate intracellular calcium
US8389567B2 (en) 2007-12-12 2013-03-05 Calcimedica, Inc. Compounds that modulate intracellular calcium
CA2734500A1 (en) 2008-08-27 2010-03-11 Calcimedica Inc. Compounds that modulate intracellular calcium
US8524763B2 (en) 2008-09-22 2013-09-03 Calcimedica, Inc. Inhibitors of store operated calcium release
AU2009300318A1 (en) 2008-10-01 2010-04-08 Synta Pharmaceuticals Corp. Compounds for inflammation and immune-related uses
EP2477982A4 (en) 2009-09-16 2013-04-03 Calcimedica Inc COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM
US8377970B2 (en) * 2009-10-08 2013-02-19 Rhizen Pharmaceuticals Sa Modulators of calcium release-activated calcium channel
MX2013002011A (es) 2010-08-20 2013-03-25 Gruenenthal Gmbh Derivados ciclicos de carboxamida y urea sustituidos como ligandos del receptor vainiloide.
JP5387541B2 (ja) 2010-10-29 2014-01-15 住友電装株式会社 グロメット
KR101860286B1 (ko) 2010-10-30 2018-05-21 루핀 리미티드 Crac 조절제인 옥사졸린과 이소옥사졸린 유도체
WO2012062462A1 (en) 2010-11-10 2012-05-18 Grünenthal GmbH Substituted heteroaromatic carboxamide and urea derivatives as vanilloid receptor ligands
PL2704701T3 (pl) 2011-05-03 2018-06-29 PRCL Research Inc. Związki do zastosowań związanych ze stanami zapalnymi i immunologicznymi
US9856240B2 (en) 2011-10-19 2018-01-02 Calcimedica, Inc. Compounds that modulate intracellular calcium
CA2853469A1 (en) 2011-10-19 2013-04-25 Calcimedica, Inc. Compounds that modulate intracellular calcium

Also Published As

Publication number Publication date
US20150111925A1 (en) 2015-04-23
EP2844656A1 (en) 2015-03-11
AU2013255441B2 (en) 2017-11-09
US9409898B2 (en) 2016-08-09
CA2871222A1 (en) 2013-11-07
ZA201407668B (en) 2015-11-25
WO2013164773A1 (en) 2013-11-07
AU2013255441A1 (en) 2014-11-13
US20160304507A1 (en) 2016-10-20

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