IN2014MN02127A - - Google Patents
Info
- Publication number
- IN2014MN02127A IN2014MN02127A IN2127MUN2014A IN2014MN02127A IN 2014MN02127 A IN2014MN02127 A IN 2014MN02127A IN 2127MUN2014 A IN2127MUN2014 A IN 2127MUN2014A IN 2014MN02127 A IN2014MN02127 A IN 2014MN02127A
- Authority
- IN
- India
- Prior art keywords
- compounds
- calcium
- crac
- channel
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to compounds described herein Formula (I) and pharmaceutical acceptable salts thereof which modulate the activity of calcium release activated calcium (CRAC) channel. The invention also describes the compounds of Formula (I) and pharmaceutical compositions containing such compounds thereof for treating managing and/or lessening the severity of diseases disorders syndromes or conditions associated with the modulation of calcium release activated calcium (CRAC) channel.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2127MUN2014 IN2014MN02127A (en) | 2012-05-02 | 2013-05-01 |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN6KO2012 | 2012-05-02 | ||
IN1474KO2012 | 2012-12-28 | ||
PCT/IB2013/053446 WO2013164773A1 (en) | 2012-05-02 | 2013-05-01 | Substituted pyrazole compounds as crac modulators |
IN2127MUN2014 IN2014MN02127A (en) | 2012-05-02 | 2013-05-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014MN02127A true IN2014MN02127A (en) | 2015-09-11 |
Family
ID=48428566
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN2127MUN2014 IN2014MN02127A (en) | 2012-05-02 | 2013-05-01 |
Country Status (7)
Country | Link |
---|---|
US (2) | US9409898B2 (en) |
EP (1) | EP2844656A1 (en) |
AU (1) | AU2013255441B2 (en) |
CA (1) | CA2871222A1 (en) |
IN (1) | IN2014MN02127A (en) |
WO (1) | WO2013164773A1 (en) |
ZA (1) | ZA201407668B (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015197188A1 (en) * | 2014-06-24 | 2015-12-30 | Grünenthal GmbH | Pyrazolyl-based carboxamides as crac inhibitors |
WO2015197187A1 (en) * | 2014-06-24 | 2015-12-30 | Grünenthal GmbH | Pyrazolyl-based carboxamides v |
WO2016187182A1 (en) | 2015-05-18 | 2016-11-24 | Beth Israel Deaconess Medical Center, Inc. | Substance p, mast cell degranulation inhibitors, and peripheral neuropathy |
AU2019340601A1 (en) | 2018-09-14 | 2021-05-13 | Rhizen Pharmaceuticals A G | Compositions comprising a CRAC inhibitor and a corticosteroid and methods of use thereof |
US11034669B2 (en) | 2018-11-30 | 2021-06-15 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
US20220235005A1 (en) | 2019-06-06 | 2022-07-28 | Basf Se | Fungicidal n-(pyrid-3-yl)carboxamides |
CN110604735B (en) * | 2019-09-18 | 2022-10-25 | 华东师范大学 | Compound for treating hepatic fibrosis and scleroderma and application thereof |
WO2021063735A1 (en) | 2019-10-02 | 2021-04-08 | Basf Se | New bicyclic pyridine derivatives |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU751139B2 (en) * | 1997-10-13 | 2002-08-08 | Astellas Pharma Inc. | Amide derivative |
JP2002510679A (en) | 1998-04-08 | 2002-04-09 | アボット・ラボラトリーズ | Pyrazole cytokine production inhibitor |
AU4229999A (en) * | 1998-06-05 | 1999-12-20 | Boehringer Ingelheim Pharmaceuticals, Inc. | Substituted 1-(4-aminophenyl)pyrazoles and their use as anti-inflammatory agents |
DE602004030689D1 (en) | 2003-07-23 | 2011-02-03 | Synta Pharmaceuticals Corp | COMPOUNDS AGAINST INFLAMMATION AND IMMUNE-RELEVANT USES |
US7709518B2 (en) | 2004-09-21 | 2010-05-04 | Synta Pharmaceuticals Corp. | Compounds for inflammation and immune-related uses |
AU2006211646B2 (en) | 2005-01-07 | 2012-09-20 | Synta Pharmaceuticals Corp. | Compounds for inflammation and immune-related uses |
AU2006208045B2 (en) | 2005-01-25 | 2012-08-30 | Synta Pharmaceuticals Corp. | Compounds for inflammation and immune-related uses |
WO2006081389A1 (en) | 2005-01-25 | 2006-08-03 | Synta Pharmaceuticals Corp. | Thiophene compounds for inflammation and immune-related uses |
CA2639927A1 (en) | 2006-01-25 | 2007-08-02 | Synta Pharmaceuticals Corp. | Substituted biaryl compounds for inflammation and immune-related uses |
AU2007208227A1 (en) | 2006-01-25 | 2007-08-02 | Synta Pharmaceuticals Corp. | Phenyl and pyridyl compounds for inflammation and immune-related uses |
TW200806641A (en) | 2006-01-25 | 2008-02-01 | Synta Pharmaceuticals Corp | Substituted aromatic compounds for inflammation and immune-related uses |
DK1984338T3 (en) | 2006-01-31 | 2013-04-22 | Synta Pharmaceuticals Corp | Pyridylphenyl compounds for inflammation and immune-related applications |
WO2009017819A1 (en) | 2007-08-01 | 2009-02-05 | Synta Pharmaceuticals Corp. | Pyridine compounds for inflammation and immune-related uses |
MX2010002712A (en) | 2007-09-10 | 2010-06-09 | Calcimedica Inc | Compounds that modulate intracellular calcium. |
US8389567B2 (en) | 2007-12-12 | 2013-03-05 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
BRPI0917719A2 (en) | 2008-08-27 | 2019-11-19 | Calcimedica Inc | intracellular calcium modulating compounds |
US8524763B2 (en) | 2008-09-22 | 2013-09-03 | Calcimedica, Inc. | Inhibitors of store operated calcium release |
EP2350006A1 (en) | 2008-10-01 | 2011-08-03 | Synta Pharmaceuticals Corp. | Compounds for inflammation and immune-related uses |
EP2477982A4 (en) | 2009-09-16 | 2013-04-03 | Calcimedica Inc | Compounds that modulate intracellular calcium |
US8377970B2 (en) | 2009-10-08 | 2013-02-19 | Rhizen Pharmaceuticals Sa | Modulators of calcium release-activated calcium channel |
CA2806634A1 (en) | 2010-08-20 | 2012-02-23 | Gruenenthal Gmbh | Substituted cyclic carboxamide and urea derivatives as ligands of the vanilloid receptor |
JP5387541B2 (en) | 2010-10-29 | 2014-01-15 | 住友電装株式会社 | Grommet |
PL2632906T3 (en) * | 2010-10-30 | 2016-09-30 | Oxazoline and isoxazoline derivatives as crac modulators | |
EP2638034A1 (en) | 2010-11-10 | 2013-09-18 | Grünenthal GmbH | Substituted heteroaromatic carboxamide and urea derivatives as vanilloid receptor ligands |
EP2704701B1 (en) | 2011-05-03 | 2018-01-03 | PRCL Research Inc. | Compounds for inflammation and immune-related uses |
EP2768810A1 (en) | 2011-10-19 | 2014-08-27 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
US9856240B2 (en) | 2011-10-19 | 2018-01-02 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
-
2013
- 2013-05-01 IN IN2127MUN2014 patent/IN2014MN02127A/en unknown
- 2013-05-01 WO PCT/IB2013/053446 patent/WO2013164773A1/en active Application Filing
- 2013-05-01 AU AU2013255441A patent/AU2013255441B2/en not_active Expired - Fee Related
- 2013-05-01 EP EP13722112.3A patent/EP2844656A1/en not_active Withdrawn
- 2013-05-01 CA CA 2871222 patent/CA2871222A1/en not_active Abandoned
- 2013-05-01 US US14/398,161 patent/US9409898B2/en not_active Expired - Fee Related
-
2014
- 2014-10-22 ZA ZA2014/07668A patent/ZA201407668B/en unknown
-
2016
- 2016-06-28 US US15/194,795 patent/US20160304507A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2013164773A1 (en) | 2013-11-07 |
AU2013255441A1 (en) | 2014-11-13 |
EP2844656A1 (en) | 2015-03-11 |
ZA201407668B (en) | 2015-11-25 |
AU2013255441B2 (en) | 2017-11-09 |
US20150111925A1 (en) | 2015-04-23 |
CA2871222A1 (en) | 2013-11-07 |
US20160304507A1 (en) | 2016-10-20 |
US9409898B2 (en) | 2016-08-09 |
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