IN2014MN02114A - - Google Patents
Info
- Publication number
- IN2014MN02114A IN2014MN02114A IN2114MUN2014A IN2014MN02114A IN 2014MN02114 A IN2014MN02114 A IN 2014MN02114A IN 2114MUN2014 A IN2114MUN2014 A IN 2114MUN2014A IN 2014MN02114 A IN2014MN02114 A IN 2014MN02114A
- Authority
- IN
- India
- Prior art keywords
- akt3
- emt
- epithelial
- occurrence
- subject
- Prior art date
Links
- 230000007705 epithelial mesenchymal transition Effects 0.000 abstract 4
- 101150051155 Akt3 gene Proteins 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000000090 biomarker Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/11—Protein-serine/threonine kinases (2.7.11)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5073—Stem cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57496—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- G01N2333/91205—Phosphotransferases in general
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261641512P | 2012-05-02 | 2012-05-02 | |
| GB201207722A GB201207722D0 (en) | 2012-05-02 | 2012-05-02 | Method |
| PCT/IB2013/053488 WO2013164788A2 (en) | 2012-05-02 | 2013-05-02 | Method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014MN02114A true IN2014MN02114A (enrdf_load_stackoverflow) | 2015-09-04 |
Family
ID=46330714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2114MUN2014 IN2014MN02114A (enrdf_load_stackoverflow) | 2012-05-02 | 2013-05-02 |
Country Status (13)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106460067A (zh) * | 2014-07-14 | 2017-02-22 | 豪夫迈·罗氏有限公司 | 诊断方法和用于治疗成胶质细胞瘤的组合物 |
| GB201420239D0 (en) * | 2014-11-14 | 2014-12-31 | Bergenbio As | Biomarker |
| GB201512133D0 (en) * | 2015-07-10 | 2015-08-19 | Bergenbio As | Biomarkers |
| KR101941054B1 (ko) * | 2016-07-20 | 2019-01-23 | 연세대학교 산학협력단 | 암 예후 예측을 위한 조성물 및 이를 포함하는 키트 |
| US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
| KR102080384B1 (ko) * | 2018-02-28 | 2020-02-21 | 주식회사 마크로젠 | 암줄기세포 특이적 바이오마커 |
| SG11202104963WA (en) * | 2018-11-12 | 2021-06-29 | Agency Science Tech & Res | Methods for manipulating cell state transitions in cancer |
| EP4146196A4 (en) * | 2020-05-08 | 2024-06-26 | Georgiamune Inc. | AKT3 MODULATORS AND METHODS OF USE THEREOF |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6809194B1 (en) | 2000-05-10 | 2004-10-26 | Chiron Corporation | Akt3 inhibitors |
| US20040121413A1 (en) | 2002-12-20 | 2004-06-24 | Aebersold Rudolf H. | Androgen-regulated genes and uses for diagnosis, prognosis and treatment of prostate neoplastic conditions |
| WO2004086038A2 (en) * | 2003-03-28 | 2004-10-07 | Institut Curie | A method for screening compounds having the capacity to control tumor cell invasion or metastasis using constitutively active akt |
| WO2004096135A2 (en) | 2003-04-24 | 2004-11-11 | Merck & Co., Inc. | Inhibitors of akt activity |
| WO2008042867A2 (en) * | 2006-09-29 | 2008-04-10 | Emiliem Inc. | Modulators of multiple kinases |
| EP2114983B8 (en) | 2007-02-07 | 2015-02-18 | The Regents of the University of Colorado, A Body Corporate | Axl tyrosine kinase inhibitors and methods of making and using the same |
| BRPI0815563A2 (pt) * | 2007-07-12 | 2015-02-18 | Univ South Florida | Inibidores de akt/pkb com atividade antitumoral |
| US20090098594A1 (en) * | 2007-08-21 | 2009-04-16 | Nodality, Inc. | Methods for diagnosis prognosis and methods of treatment |
| US8735064B2 (en) | 2007-12-24 | 2014-05-27 | Bergenbio As | Methods for creating and identifying functional RNA interference elements |
| US8067178B2 (en) | 2008-03-14 | 2011-11-29 | Genomic Health, Inc. | Gene expression markers for prediction of patient response to chemotherapy |
| PT2387395E (pt) | 2009-01-16 | 2015-02-04 | Rigel Pharmaceuticals Inc | Inibidores de axl para utilização em terapia de combinação para prevenir, tratar ou gerir cancro metastático |
| EP2409156A4 (en) | 2009-02-06 | 2013-07-17 | H Lee Moffitt Cancer Ct & Res | PHOSPHORYLATION OF ACT-TYROSINE 176 AS CANCER BIOMARKER |
| JP2013520958A (ja) | 2009-03-13 | 2013-06-10 | ベルゲン テクノロジオヴェルフォリング エイエス | 上皮間葉転換のバイオマーカーとしてａｘｌを使用する方法 |
| WO2010115119A2 (en) | 2009-04-02 | 2010-10-07 | Tufts Medical Center, Inc. | Compositions and methods for diagnosis and prognosis of cancer and progression, and for screening anti-cancer agents |
| WO2011050351A2 (en) | 2009-10-23 | 2011-04-28 | The Translational Genomics Research Institute | Methods and kits used in identifying glioblastoma |
| US20120213801A1 (en) | 2009-10-30 | 2012-08-23 | Ekaterina Gresko | Phosphorylated Twist1 and cancer |
| ES2537403T3 (es) | 2010-07-27 | 2015-06-08 | Genomic Health, Inc. | Método para usar la expresión génica para determinar el pronóstico de cáncer de próstata |
| US20130171159A1 (en) * | 2010-09-10 | 2013-07-04 | Brian Arthur Hemmings | Phosphorylated twist1 and metastasis |
| US20140031251A1 (en) * | 2010-11-03 | 2014-01-30 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Methods of classifying human subjects with regard to cancer prognosis |
-
2012
- 2012-05-02 GB GB201207722A patent/GB201207722D0/en not_active Ceased
-
2013
- 2013-05-02 KR KR1020147032804A patent/KR102179389B1/ko not_active Expired - Fee Related
- 2013-05-02 IN IN2114MUN2014 patent/IN2014MN02114A/en unknown
- 2013-05-02 CA CA2871352A patent/CA2871352A1/en not_active Abandoned
- 2013-05-02 BR BR112014027219A patent/BR112014027219A2/pt not_active Application Discontinuation
- 2013-05-02 JP JP2015509554A patent/JP2015525060A/ja active Pending
- 2013-05-02 US US14/398,572 patent/US10317405B2/en not_active Expired - Fee Related
- 2013-05-02 EA EA201401201A patent/EA201401201A1/ru unknown
- 2013-05-02 CN CN201380023276.5A patent/CN104335046B/zh not_active Expired - Fee Related
- 2013-05-02 WO PCT/IB2013/053488 patent/WO2013164788A2/en active Application Filing
- 2013-05-02 EP EP13728839.5A patent/EP2845004A2/en not_active Withdrawn
- 2013-05-02 SG SG11201407032WA patent/SG11201407032WA/en unknown
- 2013-05-02 AU AU2013255456A patent/AU2013255456B2/en not_active Ceased
-
2017
- 2017-03-17 JP JP2017052865A patent/JP6738755B2/ja not_active Expired - Fee Related
-
2019
- 2019-05-10 US US16/408,816 patent/US20200072839A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BR112014027219A2 (pt) | 2017-06-27 |
| JP2015525060A (ja) | 2015-09-03 |
| GB201207722D0 (en) | 2012-06-13 |
| EP2845004A2 (en) | 2015-03-11 |
| US20150119475A1 (en) | 2015-04-30 |
| CN104335046B (zh) | 2019-10-11 |
| AU2013255456B2 (en) | 2018-07-26 |
| CN104335046A (zh) | 2015-02-04 |
| AU2013255456A1 (en) | 2014-11-13 |
| WO2013164788A3 (en) | 2014-01-23 |
| CA2871352A1 (en) | 2013-11-07 |
| US10317405B2 (en) | 2019-06-11 |
| KR20150016518A (ko) | 2015-02-12 |
| SG11201407032WA (en) | 2014-11-27 |
| EA201401201A1 (ru) | 2015-02-27 |
| US20200072839A1 (en) | 2020-03-05 |
| JP2017136077A (ja) | 2017-08-10 |
| KR102179389B1 (ko) | 2020-11-18 |
| WO2013164788A2 (en) | 2013-11-07 |
| JP6738755B2 (ja) | 2020-08-12 |
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