IN2014DN09948A - - Google Patents

Info

Publication number
IN2014DN09948A
IN2014DN09948A IN9948DEN2014A IN2014DN09948A IN 2014DN09948 A IN2014DN09948 A IN 2014DN09948A IN 9948DEN2014 A IN9948DEN2014 A IN 9948DEN2014A IN 2014DN09948 A IN2014DN09948 A IN 2014DN09948A
Authority
IN
India
Application number
Other languages
English (en)
Inventor
Peter Gagnon
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Publication of IN2014DN09948A publication Critical patent/IN2014DN09948A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/145—Extraction; Separation; Purification by extraction or solubilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
IN9948DEN2014 2012-05-31 2014-11-24 IN2014DN09948A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261653752P 2012-05-31 2012-05-31
PCT/SG2013/000049 WO2013180650A1 (en) 2012-05-31 2013-02-06 Methods for reducing levels of protein-contaminant complexes and aggregates in protein preparations by treatment with electropositive organic additives

Publications (1)

Publication Number Publication Date
IN2014DN09948A true IN2014DN09948A (zh) 2015-08-14

Family

ID=49673721

Family Applications (1)

Application Number Title Priority Date Filing Date
IN9948DEN2014 IN2014DN09948A (zh) 2012-05-31 2014-11-24

Country Status (8)

Country Link
US (1) US10246506B2 (zh)
EP (1) EP2855502B1 (zh)
JP (2) JP2015519361A (zh)
KR (1) KR102067445B1 (zh)
CN (1) CN104507953B (zh)
IN (1) IN2014DN09948A (zh)
SG (2) SG10201606990TA (zh)
WO (1) WO2013180650A1 (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014123486A1 (en) * 2013-02-06 2014-08-14 Agency For Science, Technology And Research Methods for reducing aggregate levels in protein preparations by treatment with thio-heterocyclic cations
WO2014133458A1 (en) * 2013-02-26 2014-09-04 Agency For Science, Technology And Research Protein purification in the presence of nonionic organic polymers and electropositive surfaces
US10253063B2 (en) 2013-02-28 2019-04-09 Agency For Science, Technology And Research Protein purification in the presence of nonionic organic polymers at elevated conductivity
SG11201607098SA (en) * 2014-02-27 2016-09-29 Agency Science Tech & Res Antibody purification process
SG11201607012TA (en) 2014-02-27 2016-09-29 Agency Science Tech & Res Methods for reducing aggregate content of protein preparations by treatment with aryl anions
US10478498B2 (en) 2014-06-20 2019-11-19 Reform Biologics, Llc Excipient compounds for biopolymer formulations
WO2015196091A1 (en) 2014-06-20 2015-12-23 Reform Biologics, Llc Viscosity-reducing excipient compounds for protein formulations
WO2017217930A1 (en) 2016-06-15 2017-12-21 Agency For Science, Technology And Research A method of enhancing the performance of chromatography methods for purification of proteins
US10279048B2 (en) 2016-07-13 2019-05-07 Reform Biologics, Llc Stabilizing excipients for therapeutic protein formulations
DE102016010601B4 (de) 2016-09-01 2018-11-08 Sartorius Stedim Biotech Gmbh Verfahren zur Aufreinigung von Viren oder virusähnlichen Partikeln unter Verwendung einer vernetzten Cellulosehydrat-Membran
WO2019036619A1 (en) * 2017-08-18 2019-02-21 Reform Biologics, Llc STABILIZING EXCIPIENTS FOR FORMULATIONS OF THERAPEUTIC PROTEIN
CN113493570B (zh) * 2020-04-01 2022-11-01 中国科学院理化技术研究所 一种采用尿囊素降低明胶中内毒素的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4569790A (en) * 1984-03-28 1986-02-11 Cetus Corporation Process for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositions
AU597924B2 (en) * 1985-12-11 1990-06-14 Natinco Nv Solubilization of protein aggregates
HUT72326A (en) * 1993-10-06 1996-04-29 Amgen Inc Stable protein phospholipid compositions and methods
US5691132A (en) 1994-11-14 1997-11-25 Cerus Corporation Method for inactivating pathogens in red cell compositions using quinacrine mustard
SE9500778D0 (sv) * 1995-03-03 1995-03-03 Pharmacia Ab Process for producing a protein
SE0201257D0 (sv) * 2002-04-25 2002-04-25 Medical Invest In Sweden Ab Improved Separation
CN1286453C (zh) * 2003-07-25 2006-11-29 复旦大学 一种稳定蛋白药物的方法及其在微球制备中的应用
ES2374330T3 (es) 2007-01-22 2012-02-15 Genentech, Inc. Precipitación con polielectrolito y purificación de anticuerpos.
JP5496898B2 (ja) 2007-10-12 2014-05-21 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング タンパク質リフォールディングのための方法および剤
WO2009149067A1 (en) 2008-06-03 2009-12-10 Patrys Limited Process for purification of antibodies
EP2241886A1 (en) 2009-04-15 2010-10-20 Beckman Coulter Biomedical Limited Homogeneous agglutination immunoassay method and kit for such method
CA2812058C (en) * 2010-09-20 2019-04-16 Bio-Rad Laboratories, Inc. Dissociation of product-complexed contaminants in chromatography
JP6200949B2 (ja) * 2012-05-31 2017-09-20 エイジェンシー フォー サイエンス，テクノロジー アンド リサーチ 固相ウレイドに対する生物学的標的物の選択的結合
JP6268167B2 (ja) * 2012-05-31 2018-01-24 エイジェンシー フォー サイエンス，テクノロジー アンド リサーチ タンパク質製剤中の凝集物含量を低減するために混合型多官能表面を使用する方法
CN104507955A (zh) * 2012-05-31 2015-04-08 新加坡科技研究局 采用具有多形式官能性的颗粒对免疫球蛋白g制备物的色谱纯化

Also Published As

Publication number Publication date
JP6491277B2 (ja) 2019-03-27
EP2855502A1 (en) 2015-04-08
EP2855502B1 (en) 2019-06-26
CN104507953A (zh) 2015-04-08
WO2013180650A1 (en) 2013-12-05
EP2855502A4 (en) 2016-02-17
SG10201606990TA (en) 2016-10-28
US10246506B2 (en) 2019-04-02
JP2017222699A (ja) 2017-12-21
CN104507953B (zh) 2018-05-18
SG11201407812SA (en) 2014-12-30
JP2015519361A (ja) 2015-07-09
KR20150028231A (ko) 2015-03-13
US20150148526A1 (en) 2015-05-28
KR102067445B1 (ko) 2020-01-17

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