IN2014DN09791A - - Google Patents

Info

Publication number
IN2014DN09791A
IN2014DN09791A IN9791DEN2014A IN2014DN09791A IN 2014DN09791 A IN2014DN09791 A IN 2014DN09791A IN 9791DEN2014 A IN9791DEN2014 A IN 9791DEN2014A IN 2014DN09791 A IN2014DN09791 A IN 2014DN09791A
Authority
IN
India
Prior art keywords
conjugates
disclosed
meningococcal
immunogenic
against meningococcal
Prior art date
Application number
Other languages
English (en)
Inventor
Che-Hung Robert Lee
Valerian B Pinto
Original Assignee
Us Sec Dep Of Health & Human Services
Us Government
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Sec Dep Of Health & Human Services, Us Government filed Critical Us Sec Dep Of Health & Human Services
Publication of IN2014DN09791A publication Critical patent/IN2014DN09791A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
IN9791DEN2014 2012-05-24 2014-11-19 IN2014DN09791A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261651382P 2012-05-24 2012-05-24
PCT/US2013/042428 WO2013177397A1 (en) 2012-05-24 2013-05-23 Multivalent meningococcal conjugates and methods for preparing cojugates

Publications (1)

Publication Number Publication Date
IN2014DN09791A true IN2014DN09791A (ja) 2015-07-31

Family

ID=48579502

Family Applications (1)

Application Number Title Priority Date Filing Date
IN9791DEN2014 IN2014DN09791A (ja) 2012-05-24 2014-11-19

Country Status (4)

Country Link
US (2) US9427476B2 (ja)
CN (1) CN104428008B (ja)
IN (1) IN2014DN09791A (ja)
WO (1) WO2013177397A1 (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100338218C (zh) 1999-05-19 2007-09-19 启龙股份公司 组合式奈瑟球菌组合物
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
EP2886551A3 (en) 2008-02-21 2015-09-23 Novartis AG Meningococcal fhbp polypeptides
JP5597245B2 (ja) 2009-03-24 2014-10-01 ノバルティス アーゲー アジュバント添加した髄膜炎菌h因子結合タンパク質
US9427476B2 (en) * 2012-05-24 2016-08-30 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Multivalent meningococcal conjugates and methods for preparing conjugates
CA2876138C (en) * 2012-06-14 2023-09-19 Novartis Ag Vaccines for serogroup x meningococcus
WO2018045286A1 (en) 2016-09-02 2018-03-08 Sanofi Pasteur, Inc. Neisseria meningitidis vaccine
CN108144056A (zh) * 2016-12-02 2018-06-12 武汉博沃生物科技有限公司 多价肺炎球菌多糖结合疫苗及其制备方法
CN107151270B (zh) * 2017-03-22 2018-07-31 武汉博沃生物科技有限公司 重组ΔfHbp-NadA融合蛋白载体及其制备方法和应用
GB202016604D0 (en) * 2020-10-20 2020-12-02 Univ Of Oxford Compositions and methods for inducing an immune response
CN117643624A (zh) * 2024-01-30 2024-03-05 成都康华生物制品股份有限公司 一种双价多糖结合疫苗的制备方法及双价多糖结合疫苗

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6429199B1 (en) 1994-07-15 2002-08-06 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules for activating dendritic cells
US6239116B1 (en) 1994-07-15 2001-05-29 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US6207646B1 (en) 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
DK0772619T4 (da) 1994-07-15 2011-02-21 Univ Iowa Res Found Immunmodulatoriske oligonukleotider
EP1039935A4 (en) 1997-02-28 2005-04-27 Univ Iowa Res Found USE OF NUCLEIC ACIDS CONTAINING NON-METHYLATED CpG DINUCLEOTIDES IN THE TREATMENT OF LIPOPOLYSACCHARIDE-ASSOCIATED ILLNESSES
US6406705B1 (en) 1997-03-10 2002-06-18 University Of Iowa Research Foundation Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
US6339068B1 (en) 1997-05-20 2002-01-15 University Of Iowa Research Foundation Vectors and methods for immunization or therapeutic protocols
WO1999051259A2 (en) 1998-04-03 1999-10-14 University Of Iowa Research Foundation Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines
CA2403620C (en) 2000-03-20 2012-01-10 Massachusetts Institute Of Technology Inorganic chromophore bioconjugates
GB0220197D0 (en) 2002-08-30 2002-10-09 Univ Utrecht Refolding method
CN100423774C (zh) 2003-08-06 2008-10-08 美国政府健康及人类服务部 制备多糖-蛋白轭合物疫苗的方法
US8048432B2 (en) 2003-08-06 2011-11-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Polysaccharide-protein conjugate vaccines
EP3006041B1 (en) 2006-03-17 2017-11-29 The Government of the United States of America, as represented by The Secretary, Department of Health and Human Services Methods for preparing complex multivalent immunogenic conjugates
EP2886551A3 (en) 2008-02-21 2015-09-23 Novartis AG Meningococcal fhbp polypeptides
BRPI1009829A2 (pt) 2009-03-24 2016-11-16 Novartis Ag combinações de proteína de ligação de fator h meningocócico e conjugados de sacarídeos pneumocócicos
US20120064104A1 (en) 2009-03-24 2012-03-15 Novartis Ag Combinations including pneumococcal serotype 14 saccharide
EP2538969A4 (en) 2010-02-22 2013-11-27 Liquidia Technologies Inc VACCINES FROM POLYSACCHARIDE PARTICLES
WO2011110635A1 (en) 2010-03-10 2011-09-15 Glaxosmithkline Biologicals S.A. Immunogenic composition
US9427476B2 (en) * 2012-05-24 2016-08-30 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Multivalent meningococcal conjugates and methods for preparing conjugates

Also Published As

Publication number Publication date
US20150110829A1 (en) 2015-04-23
US9427476B2 (en) 2016-08-30
CN104428008B (zh) 2020-10-09
WO2013177397A1 (en) 2013-11-28
US9956278B2 (en) 2018-05-01
US20160331824A1 (en) 2016-11-17
CN104428008A (zh) 2015-03-18

Similar Documents

Publication Publication Date Title
IN2014DN09791A (ja)
PH12018501517A1 (en) Neisseria meningitidis compositions and methods thereof
EP4286000A3 (en) Streptococcus pneumoniae capsular polysaccharides and conjugates thereof
MX2013013111A (es) Composicion inmunogenica que presenta antigeno multiple, y metodos y usos de la misma.
MY167579A (en) Glycoconjugation processes and compositions
MY169837A (en) Immunogenic compositions of staphylococcus aureus antigens
MX371454B (es) Polisacaridos capsulares de streptococcus pneumoniae y conjugados de los mismos.
IN2014DN08830A (ja)
GB201101665D0 (en) Immunogenic compositions
EP3616716A3 (en) Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
PH12013502192A1 (en) Antibodies against human angiopoietin 2
MX2015002482A (es) Composicion inmunogenica.
MY166172A (en) Non-lipidated variants of neisseria meningitidis orf2086 antigens
WO2011098962A3 (fr) Polysaccharides anioniques fonctionnalisés par au moins deux groupements hydrophobes portés par un spacer au moins trivalent
MX2014009250A (es) Composicion inmunogenica.
BR112015008419A8 (pt) composição imunogênica, vacina, e, uso de uma composição imunogênica ou de uma vacina
WO2014207708A3 (en) Amino acid and peptide conjugates and conjugation process
MX2014014576A (es) Vacunas para meningococo de serogrupo x.
MX2018010920A (es) Nuevos conjugados de polisacarido-proteina, y procedimiento para obtener los mismos.
MX2020002084A (es) Conjugados de peptido, proceso de conjugacion y usos de los mismos.
IN2012DN01695A (ja)
WO2012103444A3 (en) Immunogenic compositions and reagents for preparing
WO2015181834A3 (en) Novel semi-synthetic meningococcal conjugate vaccine
EP3448424A4 (en) NOVEL CONJUGATE FOR THE VACCINATION OF TYPHUS WITH CHEMICAL CONJUGATE OF VI-POLYSACCHARIDE AND FLAGELLIN, METHOD FOR THE PRODUCTION THEREOF AND COMPOSITION WITH THE CONJUGATE
MX2013002841A (es) Composiciones inmunogenas.