IN2014DN09053A - - Google Patents

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Publication number
IN2014DN09053A
IN2014DN09053A IN9053DEN2014A IN2014DN09053A IN 2014DN09053 A IN2014DN09053 A IN 2014DN09053A IN 9053DEN2014 A IN9053DEN2014 A IN 9053DEN2014A IN 2014DN09053 A IN2014DN09053 A IN 2014DN09053A
Authority
IN
India
Prior art keywords
tetrahydrolactoylpterin
lactoylpterin
sepiapterin
reaction formula
good yield
Prior art date
Application number
Other languages
English (en)
Inventor
Hiroshi Yoshino
Taichi Komoda
Yuichi Shiro
Shunichi Murata
Shizuaki Murata
Yasuhiro Kuroda
Original Assignee
Shiratori Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shiratori Pharm filed Critical Shiratori Pharm
Publication of IN2014DN09053A publication Critical patent/IN2014DN09053A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • C07D475/02Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Peptides Or Proteins (AREA)
IN9053DEN2014 2012-05-07 2013-05-07 IN2014DN09053A (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012105758 2012-05-07
JP2012247255 2012-11-09
PCT/JP2013/062817 WO2013168693A1 (ja) 2012-05-07 2013-05-07 セピアプテリン及びテトラヒドロラクトイルプテリンの製造法

Publications (1)

Publication Number Publication Date
IN2014DN09053A true IN2014DN09053A (pl) 2015-05-22

Family

ID=49550728

Family Applications (1)

Application Number Title Priority Date Filing Date
IN9053DEN2014 IN2014DN09053A (pl) 2012-05-07 2013-05-07

Country Status (7)

Country Link
US (1) US9181254B2 (pl)
EP (1) EP2848619B1 (pl)
JP (1) JP6084967B2 (pl)
CN (1) CN104736539B (pl)
ES (1) ES2681345T3 (pl)
IN (1) IN2014DN09053A (pl)
WO (1) WO2013168693A1 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5066756B2 (ja) 2010-04-22 2012-11-07 学校法人日本大学 脳機能障害予防・改善用の薬剤及び飲食物
JP6809781B2 (ja) * 2015-11-18 2021-01-06 白鳥製薬株式会社 プテリン誘導体又はその塩
WO2018102314A1 (en) 2016-11-29 2018-06-07 Censa Pharmaceuticals Inc. Polymorphic form of sepiapterin
JP7148533B2 (ja) * 2016-11-29 2022-10-05 ピーティーシー セラピューティクス エムピー,インコーポレイテッド セピプテリン及びその塩の多形
WO2019046849A1 (en) 2017-09-01 2019-03-07 Censa Pharmaceuticals Inc. PHARMACEUTICAL COMPOSITION COMPRISING SEPAPTERINE AND USES THEREOF
DK3801536T3 (da) 2018-05-30 2024-08-19 Ptc Therapeutics Mp Inc Indgivelse af sepiapterin uden mad til anvendelse i en fremgangsmåde til at øge sepiapterinplasmaeksponering
CN112543758A (zh) * 2018-05-30 2021-03-23 Ptc医疗Mp公司 墨蝶呤的药学上可接受的盐

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713454A (en) 1985-01-28 1987-12-15 Shiratori Pharmaceutical Co., Ltd. Preparation process of (6R)-tetrahydro-L-biopterin
JPS61172877A (ja) 1985-01-28 1986-08-04 Shiratori Seiyaku Kk (6r)−テトラヒドロ−l−バイオプテリンの製造方法
JP5184783B2 (ja) * 2003-11-17 2013-04-17 バイオマリン ファーマシューティカル インコーポレイテッド テトラヒドロビオプテリン、及びテトラヒドロビオプテリン類似体の製造方法
JP2011011976A (ja) 2007-10-10 2011-01-20 Shiratori Pharmaceutical Co Ltd プテリジン化合物及びl−ビオプテリンの製造方法
JP5066756B2 (ja) 2010-04-22 2012-11-07 学校法人日本大学 脳機能障害予防・改善用の薬剤及び飲食物

Also Published As

Publication number Publication date
CN104736539B (zh) 2017-09-01
WO2013168693A1 (ja) 2013-11-14
US9181254B2 (en) 2015-11-10
EP2848619A4 (en) 2015-11-04
EP2848619A1 (en) 2015-03-18
JPWO2013168693A1 (ja) 2016-01-07
CN104736539A (zh) 2015-06-24
ES2681345T3 (es) 2018-09-12
EP2848619B1 (en) 2018-07-11
US20150119574A1 (en) 2015-04-30
JP6084967B2 (ja) 2017-02-22

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