IN2014DN09053A - - Google Patents
Download PDFInfo
- Publication number
- IN2014DN09053A IN2014DN09053A IN9053DEN2014A IN2014DN09053A IN 2014DN09053 A IN2014DN09053 A IN 2014DN09053A IN 9053DEN2014 A IN9053DEN2014 A IN 9053DEN2014A IN 2014DN09053 A IN2014DN09053 A IN 2014DN09053A
- Authority
- IN
- India
- Prior art keywords
- tetrahydrolactoylpterin
- lactoylpterin
- sepiapterin
- reaction formula
- good yield
- Prior art date
Links
- SAJOEDCQNIZTPA-UHFFFAOYSA-N 2-amino-1-(2-hydroxypropanoyl)-2,3,4a,5-tetrahydropteridin-4-one Chemical compound CC(O)C(=O)N1C(N)NC(=O)C2NC=CN=C12 SAJOEDCQNIZTPA-UHFFFAOYSA-N 0.000 abstract 2
- VZPVHFFRKWFPLX-UHFFFAOYSA-N 2-hydroxy-N-(4-oxo-3H-pteridin-2-yl)propanamide Chemical compound CC(O)C(=O)Nc1nc2nccnc2c(=O)[nH]1 VZPVHFFRKWFPLX-UHFFFAOYSA-N 0.000 abstract 2
- VPVOXUSPXFPWBN-UHFFFAOYSA-N L-sepiapterin Natural products N1=C(N)NC(=O)C2=C1NCC(C(=O)C(O)C)=N2 VPVOXUSPXFPWBN-UHFFFAOYSA-N 0.000 abstract 2
- VPVOXUSPXFPWBN-VKHMYHEASA-N sepiapterin Chemical compound N1C(N)=NC(=O)C2=C1NCC(C(=O)[C@@H](O)C)=N2 VPVOXUSPXFPWBN-VKHMYHEASA-N 0.000 abstract 2
- 229940126478 sepiapterin Drugs 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
- C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012105758 | 2012-05-07 | ||
| JP2012247255 | 2012-11-09 | ||
| PCT/JP2013/062817 WO2013168693A1 (ja) | 2012-05-07 | 2013-05-07 | セピアプテリン及びテトラヒドロラクトイルプテリンの製造法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN09053A true IN2014DN09053A (enrdf_load_html_response) | 2015-05-22 |
Family
ID=49550728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN9053DEN2014 IN2014DN09053A (enrdf_load_html_response) | 2012-05-07 | 2013-05-07 |
Country Status (7)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8438940B2 (en) * | 2008-02-21 | 2013-05-14 | Teikoku Seiyaku Co., Ltd. | Apparatus for simulatively measuring environment of wound dressing on skin and measuring method therefor |
| WO2011132435A1 (ja) | 2010-04-22 | 2011-10-27 | 学校法人日本大学 | 脳機能障害予防・改善用の薬剤及び飲食物 |
| JP6809781B2 (ja) * | 2015-11-18 | 2021-01-06 | 白鳥製薬株式会社 | プテリン誘導体又はその塩 |
| KR102789662B1 (ko) * | 2016-11-29 | 2025-04-03 | 피티씨 테라퓨틱스 엠피, 인크. | 세피아프테린의 다형체 및 그의 염 |
| CN110312721A (zh) * | 2016-11-29 | 2019-10-08 | 显莎制药公司 | 墨蝶呤的多晶型物 |
| JP2020532535A (ja) | 2017-09-01 | 2020-11-12 | ピーティーシー セラピューティクス エムピー，インコーポレイテッド | セピアプテリンを含む医薬組成物及びその使用 |
| US11617752B2 (en) | 2018-05-30 | 2023-04-04 | Ptc Therapeutics Mp, Inc. | Methods for increasing sepiapterin plasma exposure |
| BR112020024332A2 (pt) | 2018-05-30 | 2021-02-23 | Ptc Therapeutics Mp, Inc. | sais farmaceuticamente aceitáveis de sepiapterina |
| US12257252B2 (en) | 2018-05-30 | 2025-03-25 | Ptc Therapeutics Mp, Inc. | Compositions and methods for increasing tetrahydrobiopterin plasma exposure |
| CN117088883A (zh) * | 2022-12-05 | 2023-11-21 | 哈尔滨工业大学（深圳） | 一种以Pd/Al2O3为催化剂连续加氢制备四氢叶酸的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61172877A (ja) * | 1985-01-28 | 1986-08-04 | Shiratori Seiyaku Kk | （６ｒ）−テトラヒドロ−ｌ−バイオプテリンの製造方法 |
| CA1262347A (en) | 1985-01-28 | 1989-10-17 | Suntory Limited | Preparation process of (6r)-tetrahydro-l-biopterin |
| JP5184783B2 (ja) * | 2003-11-17 | 2013-04-17 | バイオマリン ファーマシューティカル インコーポレイテッド | テトラヒドロビオプテリン、及びテトラヒドロビオプテリン類似体の製造方法 |
| JP2011011976A (ja) | 2007-10-10 | 2011-01-20 | Shiratori Pharmaceutical Co Ltd | プテリジン化合物及びｌ−ビオプテリンの製造方法 |
| WO2011132435A1 (ja) | 2010-04-22 | 2011-10-27 | 学校法人日本大学 | 脳機能障害予防・改善用の薬剤及び飲食物 |
-
2013
- 2013-05-07 JP JP2014514717A patent/JP6084967B2/ja active Active
- 2013-05-07 ES ES13787263.6T patent/ES2681345T3/es active Active
- 2013-05-07 US US14/398,884 patent/US9181254B2/en active Active
- 2013-05-07 EP EP13787263.6A patent/EP2848619B1/en active Active
- 2013-05-07 IN IN9053DEN2014 patent/IN2014DN09053A/en unknown
- 2013-05-07 CN CN201380022709.5A patent/CN104736539B/zh active Active
- 2013-05-07 WO PCT/JP2013/062817 patent/WO2013168693A1/ja active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| US9181254B2 (en) | 2015-11-10 |
| ES2681345T3 (es) | 2018-09-12 |
| WO2013168693A1 (ja) | 2013-11-14 |
| CN104736539A (zh) | 2015-06-24 |
| US20150119574A1 (en) | 2015-04-30 |
| JPWO2013168693A1 (ja) | 2016-01-07 |
| CN104736539B (zh) | 2017-09-01 |
| EP2848619A4 (en) | 2015-11-04 |
| JP6084967B2 (ja) | 2017-02-22 |
| EP2848619B1 (en) | 2018-07-11 |
| EP2848619A1 (en) | 2015-03-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IN2014DN09053A (enrdf_load_html_response) | ||
| MX2015002616A (es) | Sintesis de bis(fluorosulfonil)imida. | |
| MX353553B (es) | Metodo para producir derivados de 4,4-difluoro-3,4-dihidroisoquino lina. | |
| AP3450A (en) | Process for the synthesis of methanol | |
| MX370649B (es) | Proceso para la preparacion de teneligliptina. | |
| WO2015008218A3 (en) | Process for the preparation of suvorexant and intermediates useful in the synthesis of suvorexant | |
| MY192466A (en) | Processes for the preparation of an apoptosis-inducing agent | |
| IN2015DN01061A (enrdf_load_html_response) | ||
| MX2015007645A (es) | Cyanobacterium sp. para produccion de compuestos. | |
| MX2013013463A (es) | Nuevo procedimiento para la síntesis de rifaximina y una nueva forma pseudocristalina de rifaximina obtenida con el mismo. | |
| PH12015501807A1 (en) | Vortioxetine manufacturing process | |
| MX362689B (es) | Procedimiento de preparacion de derivados de acido 3,5-bis(fluoroalquil)pirazol-4-carboxilico y 3,5-bis(fluoroalquil) pirazoles. | |
| MX2016005496A (es) | Sintesis de fluorotrifluorometilsulfonil-imida. | |
| MX2015013589A (es) | Proceso e intermediario para la preparacion de pregabalina. | |
| UA119435C2 (uk) | Об'єднаний спосіб одержання метанолу і метилацетату | |
| PH12015502121A1 (en) | Novel processes for producing sovaprevir | |
| IN2014DN06192A (enrdf_load_html_response) | ||
| NZ720106A (en) | A process for the preparation of regadenoson | |
| MX343856B (es) | Procedimiento para la preparación de derivados 1-h-pirrolidin-2,4-diona. | |
| MX2014003936A (es) | Procedimiento para preparar ditiina-tetracarboximidas. | |
| EP2714766A4 (en) | METHOD FOR PRODUCING POLYMERS THROUGH COUPLING REACTIONS | |
| MX2013002395A (es) | Procedimiento de preparacion de ditiin-tetracarboximidas. | |
| MY156773A (en) | Preparing ether carboxylates | |
| MX2015017747A (es) | Proceso para producir 2-fenil-1, 3-benzoxazoles. | |
| PH12014501760A1 (en) | Method for stereoselective synthesis of 1,4-protected 9-hydroxy-5-oxo-1,4-diaza-spiro[5.5]undecanes |