IN2014DN08781A - - Google Patents
Info
- Publication number
- IN2014DN08781A IN2014DN08781A IN8781DEN2014A IN2014DN08781A IN 2014DN08781 A IN2014DN08781 A IN 2014DN08781A IN 8781DEN2014 A IN8781DEN2014 A IN 8781DEN2014A IN 2014DN08781 A IN2014DN08781 A IN 2014DN08781A
- Authority
- IN
- India
- Prior art keywords
- conjugates
- particles
- assemble
- peptide
- agents
- Prior art date
Links
- 239000000562 conjugate Substances 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 239000002539 nanocarrier Substances 0.000 abstract 1
- 239000000863 peptide conjugate Substances 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Optics & Photonics (AREA)
- Inorganic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261622330P | 2012-04-10 | 2012-04-10 | |
US201261668923P | 2012-07-06 | 2012-07-06 | |
PCT/US2013/035924 WO2013155152A1 (en) | 2012-04-10 | 2013-04-10 | Bis-polymer lipid-peptide conjugates and nanoparticles thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014DN08781A true IN2014DN08781A (de) | 2015-05-22 |
Family
ID=49328119
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN8781DEN2014 IN2014DN08781A (de) | 2012-04-10 | 2013-04-10 |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP2841083B1 (de) |
JP (2) | JP6426600B2 (de) |
KR (1) | KR20140143838A (de) |
CN (1) | CN104379158A (de) |
AU (1) | AU2013245989B2 (de) |
CA (1) | CA2869984C (de) |
IL (1) | IL235167A0 (de) |
IN (1) | IN2014DN08781A (de) |
MX (1) | MX2014012271A (de) |
RU (1) | RU2014144945A (de) |
WO (1) | WO2013155152A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9949927B2 (en) | 2012-04-10 | 2018-04-24 | The Regents Of The University Of California | Bis-polymer lipid-peptide conjugates and nanoparticles thereof |
JP6742982B2 (ja) | 2015-02-23 | 2020-08-19 | 日本化薬株式会社 | 生理活性物質結合ブロック共重合体 |
US10449259B2 (en) | 2015-10-02 | 2019-10-22 | Cornell University | Enzyme-responsive peptide nanofiber compositions and uses thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2324540T3 (es) | 1998-05-27 | 2009-08-10 | Genzyme Corporation | Vectores aav para la fabricacion de medicamentos para la administracion potenciada por conveccion. |
WO2003022250A2 (en) * | 2001-09-10 | 2003-03-20 | Celator Technologies Inc. | Unilamellar vesicles stabilized with short chain hydrophilic polymers |
WO2009059450A1 (en) * | 2007-11-05 | 2009-05-14 | Shanghai Jiaotong University | Peptide ligand directed drug delivery |
JP2011520962A (ja) * | 2008-05-19 | 2011-07-21 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | 新規カチオン性脂質を含む方法及び組成物 |
WO2010114632A2 (en) * | 2009-04-03 | 2010-10-07 | University Of Houston | Metal nanoparticles functionalized with rationally designed coatings and uses thereof |
BR112012012151B8 (pt) * | 2009-12-03 | 2021-05-25 | Jiangsu Hengrui Medicine Co | lipossoma de irinotecano ou cloridrato de irinotecano, método de preparação do mesmo, bem como injeção de lipossoma e processo de preparação da mesma |
WO2011112999A2 (en) * | 2010-03-12 | 2011-09-15 | The Regents Of The University Of California | Lipid-peptide-polymer conjugates and nanoparticles thereof |
-
2013
- 2013-04-10 WO PCT/US2013/035924 patent/WO2013155152A1/en active Application Filing
- 2013-04-10 RU RU2014144945A patent/RU2014144945A/ru not_active Application Discontinuation
- 2013-04-10 KR KR1020147031418A patent/KR20140143838A/ko not_active Application Discontinuation
- 2013-04-10 MX MX2014012271A patent/MX2014012271A/es unknown
- 2013-04-10 CA CA2869984A patent/CA2869984C/en active Active
- 2013-04-10 CN CN201380029919.7A patent/CN104379158A/zh active Pending
- 2013-04-10 IN IN8781DEN2014 patent/IN2014DN08781A/en unknown
- 2013-04-10 EP EP13776184.7A patent/EP2841083B1/de active Active
- 2013-04-10 AU AU2013245989A patent/AU2013245989B2/en active Active
- 2013-04-10 JP JP2015505867A patent/JP6426600B2/ja active Active
-
2014
- 2014-10-19 IL IL235167A patent/IL235167A0/en unknown
-
2018
- 2018-05-01 JP JP2018088026A patent/JP2018150327A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2869984A1 (en) | 2013-10-17 |
JP6426600B2 (ja) | 2018-11-21 |
RU2014144945A (ru) | 2016-05-27 |
CN104379158A (zh) | 2015-02-25 |
IL235167A0 (en) | 2014-12-31 |
CA2869984C (en) | 2021-08-17 |
JP2018150327A (ja) | 2018-09-27 |
MX2014012271A (es) | 2015-05-11 |
EP2841083A1 (de) | 2015-03-04 |
AU2013245989B2 (en) | 2017-03-30 |
EP2841083A4 (de) | 2016-07-13 |
AU2013245989A1 (en) | 2014-10-30 |
KR20140143838A (ko) | 2014-12-17 |
WO2013155152A1 (en) | 2013-10-17 |
EP2841083B1 (de) | 2020-08-05 |
JP2015520126A (ja) | 2015-07-16 |
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