IN2014CN02807A - - Google Patents

Download PDF

Info

Publication number
IN2014CN02807A
IN2014CN02807A IN2807CHN2014A IN2014CN02807A IN 2014CN02807 A IN2014CN02807 A IN 2014CN02807A IN 2807CHN2014 A IN2807CHN2014 A IN 2807CHN2014A IN 2014CN02807 A IN2014CN02807 A IN 2014CN02807A
Authority
IN
India
Prior art keywords
hcv
compound
rsndathe
tetrahydrocyclopropa
indolo
Prior art date
Application number
Other languages
English (en)
Inventor
Zhizhen Barbara Zheng
Stanley Dandrea
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of IN2014CN02807A publication Critical patent/IN2014CN02807A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IN2807CHN2014 2011-10-20 2012-10-17 IN2014CN02807A (xx)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161549450P 2011-10-20 2011-10-20
PCT/US2012/060537 WO2013059265A1 (en) 2011-10-20 2012-10-17 A compound for the treatment of hepatitis c

Publications (1)

Publication Number Publication Date
IN2014CN02807A true IN2014CN02807A (xx) 2015-07-03

Family

ID=47144132

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2807CHN2014 IN2014CN02807A (xx) 2011-10-20 2012-10-17

Country Status (10)

Country Link
US (1) US8716275B2 (xx)
EP (1) EP2768831B1 (xx)
JP (1) JP2014530860A (xx)
CN (1) CN104203949B (xx)
AR (1) AR088470A1 (xx)
ES (1) ES2559295T3 (xx)
IN (1) IN2014CN02807A (xx)
TW (1) TW201323426A (xx)
UY (1) UY34400A (xx)
WO (1) WO2013059265A1 (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150045608A1 (en) 2011-10-20 2015-02-12 Unacuna, Llc Infant calming/sleep-aid, sids prevention device, and method of use
EP2792360A1 (en) 2013-04-18 2014-10-22 IP Gesellschaft für Management mbH (1aR,12bS)-8-cyclohexyl-11-fluoro-N-((1-methylcyclopropyl)sulfonyl)-1a-((3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl)-1,1a,2,2b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide for use in treating HCV

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7348425B2 (en) * 2004-08-09 2008-03-25 Bristol-Myers Squibb Company Inhibitors of HCV replication
US7399758B2 (en) * 2005-09-12 2008-07-15 Meanwell Nicholas A Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors
WO2007092000A1 (en) * 2006-02-06 2007-08-16 Bristol-Myers Squibb Company Inhibitors of hcv replication
US7456166B2 (en) * 2006-05-17 2008-11-25 Bristol-Myers Squibb Company Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors
CN101443336B (zh) * 2006-05-17 2012-07-04 百时美施贵宝公司 环丙基稠合的[吲哚]并[苯并氮杂*]hcv ns5b抑制剂
US7547690B2 (en) * 2007-03-14 2009-06-16 Bristol-Myers Squibb Company Compounds for the treatment of Hepatitis C
US8129367B2 (en) * 2007-11-21 2012-03-06 Bristol-Myers Squibb Company Compounds for the treatment of Hepatitis C
TWI454476B (zh) * 2008-07-08 2014-10-01 Tibotec Pharm Ltd 用作ｃ型肝炎病毒抑制劑之巨環吲哚衍生物

Also Published As

Publication number Publication date
JP2014530860A (ja) 2014-11-20
WO2013059265A1 (en) 2013-04-25
EP2768831A1 (en) 2014-08-27
CN104203949A (zh) 2014-12-10
US8716275B2 (en) 2014-05-06
UY34400A (es) 2013-05-31
AR088470A1 (es) 2014-06-11
EP2768831B1 (en) 2015-11-25
US20130102589A1 (en) 2013-04-25
CN104203949B (zh) 2016-06-22
ES2559295T3 (es) 2016-02-11
TW201323426A (zh) 2013-06-16

Similar Documents

Publication Publication Date Title
HK1166788A1 (xx)
IN2012DN01855A (xx)
MX2013006475A (es) Inhibidores macrociclicos de virus flaviviridae.
NZ703062A (en) Macrocyclic inhibitors of flaviviridae viruses
IN2014MN02658A (xx)
TN2014000476A1 (en) D-amino acid compounds for liver disease
NZ600817A (en) Inhibitors of flaviviridae viruses
TW201129565A (en) Tricyclic heterocyclic compounds, compositions and methods of use thereof
EA201492209A1 (ru) Макроциклические ингибиторы вирусов flaviviridae
SG11201502622VA (en) PYRROLO[3,2-<i>D</i>]PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND OTHER DISEASES
IL195025A (en) History of compressed indolubenzazepine with cyclopropyl and pharmaceuticals containing them as an anti-hcv drug
NZ608720A (en) Macrocyclic proline derived hcv serine protease inhibitors
UA108221C2 (uk) Похідні тіофен-2-карбонової кислоти як інгібітори вірусів flaviviridae
EA201492204A1 (ru) Нуклеозиды на основе урацила и спирооксетана
WO2007140200A3 (en) Cyclopropyl fused indolobenzazepine hcv ns5b inhibitors
WO2007140254A3 (en) Cyclopropyl fused indolobenzazepine hcv ns5b inhibitors
MX2010008699A (es) Derivados heterociclicos como inhibidores de virus de la hepatitis c.
WO2013184876A8 (en) Benzo [c] isoxazoloazepine bromodomain inhibitors and uses thereof
PL2209789T3 (pl) Skondensowane z cyklopropylem indolobenzoazepinowe inhibitory NS5B HCV
MX2009012613A (es) Tiazoles substituidos por heteroarilo y su uso como agentes antivirales.
RS55592B1 (sr) 9-metil supstituisani heksadekahidrociklopropa(e)pirolo(1,2-a)(1,4)diazaciklopentadecinil karbamat derivati kao nestrukturalni 3 (ns3) proteazni inhibitori za lečenje infekcijavirusom hepatitisa c
GEP201706656B (en) 2-thiopyrimidinones
EP2549874A4 (en) SUBSTITUTED IMIDAZOLE [1,2-B] PYRIDAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE AS BETA-SECRETASE INHIBITORS
MY173636A (en) Method of treating dengue fever
UA102414C2 (ru) Циклоундекадепсипептидные соединения для лечения инфекций, вызванных вирусом гепатита с