IN2014CH01141A - - Google Patents

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Publication number
IN2014CH01141A
IN2014CH01141A IN1141CH2014A IN2014CH01141A IN 2014CH01141 A IN2014CH01141 A IN 2014CH01141A IN 1141CH2014 A IN1141CH2014 A IN 1141CH2014A IN 2014CH01141 A IN2014CH01141 A IN 2014CH01141A
Authority
IN
India
Prior art keywords
glucitol
anhydro
ethoxyphenyl
chloro
phenyl
Prior art date
Application number
Other languages
English (en)
Inventor
Thirumalai Rajan Srinivasan
Eswaraiah Sajja
Raghuram Suraparaju
Original Assignee
Msn Lab Private Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Msn Lab Private Ltd filed Critical Msn Lab Private Ltd
Priority to US15/303,577 priority Critical patent/US20170029398A1/en
Priority to PCT/IN2015/000119 priority patent/WO2015132803A2/en
Priority to EP15758707.2A priority patent/EP3114115A4/en
Priority to IN1141CH2014 priority patent/IN2014CH01141A/en
Publication of IN2014CH01141A publication Critical patent/IN2014CH01141A/en
Priority to US16/202,840 priority patent/US20190144411A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IN1141CH2014 2014-03-06 2015-03-06 IN2014CH01141A (enrdf_load_stackoverflow)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US15/303,577 US20170029398A1 (en) 2014-03-06 2015-03-06 Process for the preparation of (1s)-1,5-anhydro-1-c-{4-chloro-3-4[(4-ethoxyphenyl)methyl]phenyl]-glucitol and its solvate thereof
PCT/IN2015/000119 WO2015132803A2 (en) 2014-03-06 2015-03-06 Process for the preparation of (1s)-1,5-anhydro-1-c-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-d-glucitol and its solvate thereof
EP15758707.2A EP3114115A4 (en) 2014-03-06 2015-03-06 Process for the preparation of (1s)-1,5-anhydro-1-c-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-d-glucitol and its solvate thereof
IN1141CH2014 IN2014CH01141A (enrdf_load_stackoverflow) 2014-03-06 2015-03-06
US16/202,840 US20190144411A1 (en) 2014-03-06 2018-11-28 Process for the preparation of (1S)-1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl) methyl]phenyl]-D-glucitol and its solvate thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN1141CH2014 IN2014CH01141A (enrdf_load_stackoverflow) 2014-03-06 2015-03-06

Publications (1)

Publication Number Publication Date
IN2014CH01141A true IN2014CH01141A (enrdf_load_stackoverflow) 2015-09-11

Family

ID=54055961

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1141CH2014 IN2014CH01141A (enrdf_load_stackoverflow) 2014-03-06 2015-03-06

Country Status (4)

Country Link
US (2) US20170029398A1 (enrdf_load_stackoverflow)
EP (1) EP3114115A4 (enrdf_load_stackoverflow)
IN (1) IN2014CH01141A (enrdf_load_stackoverflow)
WO (1) WO2015132803A2 (enrdf_load_stackoverflow)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106316803B (zh) * 2015-06-19 2019-07-09 重庆博腾制药科技股份有限公司 一种sglt-2抑制剂中间体的合成方法
US10428053B2 (en) 2015-09-15 2019-10-01 Laurus Labs Limited Co-crystals of SGLT2 inhibitors, process for their preparation and pharmaceutical compositions thereof
US9845303B2 (en) 2015-10-19 2017-12-19 Cadila Healthcare Limited Process for the preparation of dapagliflozin
US10913762B2 (en) 2016-01-27 2021-02-09 Msn Laboratories Private Limited Process for the preparation of D-glucitol, 1,5-anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl] oxy]phenyl] methyl] phenyl]-, (1S) and its crystalline forms thereof
WO2017221211A1 (en) * 2016-06-24 2017-12-28 Biocon Limited Process for the preparation of dapagliflozin and its solvate thereof
CN107641139A (zh) * 2016-07-22 2018-01-30 江苏豪森药业集团有限公司 达格列净中间体的晶型及其制备方法
CN108610316B (zh) * 2016-12-09 2021-11-05 江苏豪森药业集团有限公司 达格列净的制备方法
WO2018142422A1 (en) * 2017-02-02 2018-08-09 Indoco Remedies Limited Process for the preparation of dapagliflozin
CN107417515A (zh) * 2017-03-30 2017-12-01 上海常丰生物医药科技有限公司 一种合成达格列净中间体的新方法
CN109705075B (zh) * 2018-12-13 2022-12-23 苏中药业集团股份有限公司 一种达格列净的纯化方法
CN110396040B (zh) * 2019-09-09 2020-12-15 东南大学 一种一锅法合成二芳基甲缩酮的方法
EP4114365A1 (en) 2020-03-05 2023-01-11 KRKA, d.d., Novo mesto Pharmaceutical composition comprising sglt2 inhibitor
CN115867538A (zh) 2020-06-05 2023-03-28 新梅斯托克公司 高纯的无定形达格列净的制备
CN111748004A (zh) * 2020-06-30 2020-10-09 药璞(上海)医药科技有限公司 一种高纯度达格列净中间体的晶型及其制备方法
CN112500267A (zh) 2020-12-04 2021-03-16 江苏慧聚药业有限公司 4-溴-2-(4’-乙氧基-苄基)-1-氯苯的制备
CN113880796A (zh) * 2021-10-14 2022-01-04 山东诚创蓝海医药科技有限公司 一种达格列净的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6515117B2 (en) * 1999-10-12 2003-02-04 Bristol-Myers Squibb Company C-aryl glucoside SGLT2 inhibitors and method
PH12000002657B1 (en) * 1999-10-12 2006-02-21 Bristol Myers Squibb Co C-aryl glucoside SGLT2 inhibitors
AU2003299966A1 (en) * 2003-01-03 2004-08-10 Bristol-Myers Squibb Company Methods of producing c-aryl glucoside sglt2 inhibitors
US7919598B2 (en) * 2006-06-28 2011-04-05 Bristol-Myers Squibb Company Crystal structures of SGLT2 inhibitors and processes for preparing same
KR101604119B1 (ko) * 2011-06-14 2016-03-16 주식회사 녹십자 신규한 c-아릴 안사 sglt2 억제제
AU2012330818B2 (en) * 2011-10-31 2015-09-17 Julian Paul Henschke Crystalline and non-crystalline forms of SGLT2 inhibitors
WO2015104658A2 (en) * 2014-01-08 2015-07-16 Dr. Reddy’S Laboratories Limited Amorphous solid dispersion of dapagliflozin and process for the preparation of amorphous dapagliflozin

Also Published As

Publication number Publication date
US20190144411A1 (en) 2019-05-16
WO2015132803A2 (en) 2015-09-11
EP3114115A2 (en) 2017-01-11
WO2015132803A3 (en) 2016-01-14
EP3114115A4 (en) 2017-08-23
US20170029398A1 (en) 2017-02-02

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